在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. EPHA8 Antibody, HRP conjugated

EPHA8 Antibody, HRP conjugated

  • 中文名稱：
    EPHA8兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA007728LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) EPHA8 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    EPHA8
  • 別名：
    EPHA8 antibody; EEK antibody; HEK3 antibody; KIAA1459Ephrin type-A receptor 8 antibody; EC 2.7.10.1 antibody; EPH- and ELK-related kinase antibody; EPH-like kinase 3 antibody; EK3 antibody; hEK3 antibody; Tyrosine-protein kinase receptor EEK antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Ephrin type-A receptor 8 protein (45-249AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth. During development of the nervous system plays also a role in axon guidance. Downstream effectors of the EPHA8 signaling pathway include FYN which promotes cell adhesion upon activation by EPHA8 and the MAP kinases in the stimulation of neurite outgrowth.
  • 基因功能參考文獻：
    1. Q-PCR and IHC staining revealed that EphA8 was highly expressed in OTSCC tissues, especially in advanced stage OTSCC tissues. Kaplan-Meier curve showed that high EphA8 expression was significantly associated with poor prognosis. PMID: 30300334
    2. High EPHA8 expression is associated with epithelial ovarian cancer. PMID: 26989075
    3. Human miR-10a and EphA8 regulate epithelial-mesenchymal transition (EMT) to affect glioma cell migration and invasion. PMID: 25683004
    4. RINL, as a GEF for Rab5 subfamily, is implicated in the EphA8-degradation pathway via its interaction with odin. PMID: 22291991
    5. role in stimulated cell migration in presnce of p110 gamma PI-3 kinase PMID: 12681484
    6. EphA8 receptor is capable of inducing a sustained increase in MAPK activity, thereby promoting neurite outgrowth in neuronal cells PMID: 15782114

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein. Cell projection. Early endosome membrane.
  • 蛋白家族：
    Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily
  • 數(shù)據(jù)庫鏈接：

    HGNC: 3391

    OMIM: 176945

    KEGG: hsa:2046

    STRING: 9606.ENSP00000166244

    UniGene: Hs.283613



主站蜘蛛池模板： 东京热无码av一区二区| 中文字幕精品久久久久人妻红杏| 国产av成人无码精品网站| 欧美性xxxxx极品少妇直播| 中文无码精品a∨在线| 色妞ww精品视频7777| av在线播放无码线| 亚洲综合av色婷婷五月蜜臀| 国产内射xxxxx在线| 特级做a爰片毛片免费看| 精品一区二区三区免费播放| 亚洲高清无在码在线电影| 国产粉嫩嫩00在线正在播放| 亚洲天天做日日做天天欢毛片 | 精品乱码久久久久久中文字幕| 日本牲交大片无遮挡| 亚洲国产日韩欧美综合a| 欧美牲交a欧美牲交aⅴ久久| 精品人妻无码区在线视频| 亚洲aⅴ在线无码播放毛片一线天| 久久精品国产99国产精2021| 中国6一12呦女精品| 西西人体做爰大胆gogo| 亚洲国产午夜精华无码福利| 亚欧成人中文字幕一区| 亚洲v天堂v手机在线| 成人天堂婷婷青青视频在线观看 | 少妇激情av一区二区三区| 护士奶头又大又软又好摸| 精品国产av一二三四区| 天堂网www中文在线| 国产精品亚洲玖玖玖在线观看 | 好吊色欧美一区二区三区视频| 久久精品国产曰本波多野结衣| 成人免费毛片内射美女app| 国精一二二产品无人区免费应用| 久久婷婷色综合一区二区| 久久本色成人综合网| 免费午夜福利不卡片在线播放| 精品久久久久久无码中文野结衣| 超清无码av最大网站|