在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ENOX2 Antibody

  • 中文名稱:
    ENOX2兔多克隆抗體
  • 貨號:
    CSB-PA007677GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    ENOX2
  • 別名:
    APK1 antibody; APK1 antigen antibody; COVA1 antibody; Cytosolic ovarian carcinoma antigen 1 antibody; Ecto NOX disulfide thiol exchanger 2 antibody; ENOX 2 antibody; ENOX2 antibody; ENOX2_HUMAN antibody; OTTHUMP00000024021 antibody; OTTHUMP00000024022 antibody; Protein disulfide-thiol oxidoreductase antibody; tNOX antibody; Tumor associated hydroquinone oxidase antibody; Tumor-associated hydroquinone oxidase antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human ENOX2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock.
  • 基因功能參考文獻:
    1. The tumor-associated NADH oxidase (tNOX)-mediated modulation of the NAD+ concentration and SIRT1 are involved in oxaliplatin-induced apoptosis. PMID: 28122359
    2. These findings not only shed light on the molecular mechanism of the anticancer properties of capsaicin, but also the transcription regulation of tNOX expression that may potentially explain how POU3F2 is associated with tumorigenesis. PMID: 27271588
    3. The findings support a role for arNOX as a major source of oxidative damage leading to cross-linking of skin proteins. PMID: 24906676
    4. The results suggest that phosphorylation of serine-504 by PKCdelta modulates the biological function of tNOX. PMID: 22659163
    5. this result suggests that hnRNP F directs formation of the exon 4 minus variant of ENOX2. PMID: 21625959
    6. increased NADH levels resulting from ENOX2 inhibition result in decreased prosurvival sphingosine-1-phosphate and increased proapoptotic ceramide, both of which may be important to initiation of the ENOX2 inhibitor-induced apoptotic cascade. PMID: 21571040
    7. ENOX2 is a dimeric protein containing 4 coppers/dimer capable of carrying out concerted four electron transfers from NADH or ubiquinol to molecular oxygen as required to form water. PMID: 20922471
    8. arNOX activity correlates with age and reaches a maximum at about age 65 in males and 55 in females. PMID: 20345278
    9. Enhanced arNOX activity correlates with age and with oxidative changes contributing to skin aging. PMID: 19734125
    10. tNOX is both necessary and sufficient for the cellular anticancer activities attributed to both EGCg and capsaicin. *tNOX enzyme PMID: 15706060
    11. results indicate that shRNA targeting of tNOX inhibits the growth of cervical cancer cells, and reduces cell migration via a decrease in the membrane association of Rac. PMID: 18023414
    12. A relationship of tNOX to unregulated growth of cancer cells was provided by data where growth of HeLa cells was inhibited by transfection with the exon 5 antisense oligonucleotides PMID: 18351130
    13. These results indicate that tNOX is suppressed during apoptosis and demonstrate that tNOX down-regulation sensitizes cells to stress-induced growth reduction, suggesting that tNOX is required for transformed cell growth. PMID: 18789934

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane. Secreted, extracellular space. Note=Extracellular and plasma membrane-associated.
  • 蛋白家族:
    ENOX family
  • 組織特異性:
    Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Not found in the serum of healthy volunteers or patients with disorders other than cancer. Probably shed in
  • 數據庫鏈接:

    HGNC: 2259

    OMIM: 300282

    KEGG: hsa:10495

    STRING: 9606.ENSP00000337146

    UniGene: Hs.171458



主站蜘蛛池模板: 无码精品国产一区二区三区免费| 亚洲综合久久一区二区| 精品无码国产污污污免费网站| 国产免费无码一区二区| 欧洲丰满少妇a毛片| 97av麻豆蜜桃一区二区| 亚洲18禁私人影院| 亚洲熟女综合一区二区三区| 亚洲人成77在线播放网站| 无码专区—va亚洲v专区| 女女互磨互喷水高潮les呻吟| 无翼乌工口肉肉无遮挡无码18| 天天躁夜夜躁狠狠躁2021| 亚洲无线卡一卡二| 亚洲欧美另类久久久精品| 国产边摸边吃奶边做爽视频| 精品久久久久久亚洲中文字幕| 亚洲精品黑牛一区二区三区| 国产精品毛片一区二区| 日本又黄又潮娇喘视频| 无码av无码天堂资源网影音先锋 | 欧美老妇与zozozo交| 亚洲色婷婷婷婷五月基地| 国产精品99久久久久久宅男小说| 日本少妇毛茸茸高潮| 国产精品爽爽久久久久久竹菊| 伊人成伊人成综合网222| 337p日本欧洲亚洲大胆精品| 奇米影视888欧美在线观看 | 无码东京热一区二区三区| 亚洲欭美日韩颜射在线| 最近2019中文字幕大全第二页| 成年奭片免费观看视频天天看| 又粗又黄又猛又爽大片免费| 女女互磨互喷水高潮les呻吟| 中文字幕日本特黄aa毛片| 国产亚洲视频在线观看网址| 国产精品人人妻人人爽人人牛| 精品偷自拍另类在线观看 | 国产亚洲精品久久久久久禁果tv| 久久人妻av一区二区软件 |