在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ENOX2 Antibody

ENOX2 Antibody

  • 中文名稱：
    ENOX2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA007677ESR1HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA007677ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA007677ESR1HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ENOX2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ENOX2
  • 別名：
    APK1 antibody; APK1 antigen antibody; COVA1 antibody; Cytosolic ovarian carcinoma antigen 1 antibody; Ecto NOX disulfide thiol exchanger 2 antibody; ENOX 2 antibody; ENOX2 antibody; ENOX2_HUMAN antibody; OTTHUMP00000024021 antibody; OTTHUMP00000024022 antibody; Protein disulfide-thiol oxidoreductase antibody; tNOX antibody; Tumor associated hydroquinone oxidase antibody; Tumor-associated hydroquinone oxidase antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Ecto-NOX disulfide-thiol exchanger 2 protein (411-610AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock.
  • 基因功能參考文獻(xiàn)：
    1. The tumor-associated NADH oxidase (tNOX)-mediated modulation of the NAD+ concentration and SIRT1 are involved in oxaliplatin-induced apoptosis. PMID: 28122359
    2. These findings not only shed light on the molecular mechanism of the anticancer properties of capsaicin, but also the transcription regulation of tNOX expression that may potentially explain how POU3F2 is associated with tumorigenesis. PMID: 27271588
    3. The findings support a role for arNOX as a major source of oxidative damage leading to cross-linking of skin proteins. PMID: 24906676
    4. The results suggest that phosphorylation of serine-504 by PKCdelta modulates the biological function of tNOX. PMID: 22659163
    5. this result suggests that hnRNP F directs formation of the exon 4 minus variant of ENOX2. PMID: 21625959
    6. increased NADH levels resulting from ENOX2 inhibition result in decreased prosurvival sphingosine-1-phosphate and increased proapoptotic ceramide, both of which may be important to initiation of the ENOX2 inhibitor-induced apoptotic cascade. PMID: 21571040
    7. ENOX2 is a dimeric protein containing 4 coppers/dimer capable of carrying out concerted four electron transfers from NADH or ubiquinol to molecular oxygen as required to form water. PMID: 20922471
    8. arNOX activity correlates with age and reaches a maximum at about age 65 in males and 55 in females. PMID: 20345278
    9. Enhanced arNOX activity correlates with age and with oxidative changes contributing to skin aging. PMID: 19734125
    10. tNOX is both necessary and sufficient for the cellular anticancer activities attributed to both EGCg and capsaicin. *tNOX enzyme PMID: 15706060
    11. results indicate that shRNA targeting of tNOX inhibits the growth of cervical cancer cells, and reduces cell migration via a decrease in the membrane association of Rac. PMID: 18023414
    12. A relationship of tNOX to unregulated growth of cancer cells was provided by data where growth of HeLa cells was inhibited by transfection with the exon 5 antisense oligonucleotides PMID: 18351130
    13. These results indicate that tNOX is suppressed during apoptosis and demonstrate that tNOX down-regulation sensitizes cells to stress-induced growth reduction, suggesting that tNOX is required for transformed cell growth. PMID: 18789934

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane. Secreted, extracellular space. Note=Extracellular and plasma membrane-associated.
  • 蛋白家族：
    ENOX family
  • 組織特異性：
    Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Not found in the serum of healthy volunteers or patients with disorders other than cancer. Probably shed in
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 2259

    OMIM: 300282

    KEGG: hsa:10495

    STRING: 9606.ENSP00000337146

    UniGene: Hs.171458



主站蜘蛛池模板： 精产国品一区二区三产区| 内射人妻无码色ab麻豆| 99久久国产综合精品麻豆| 在线播放五十路熟妇| 九九视频国产免| 色综合亚洲一区二区小说| 婷婷网色偷偷亚洲男人甘肃| 狠狠色噜噜狠狠狠7777奇米| 精品久久久无码中文字幕边打电话| 交换交换乱杂烩系列yy| 亚洲 欧美 中文 日韩aⅴ| 国产女人乱人伦精品一区二区| 国产麻豆精品一区| 失禁潮痉挛潮喷av在线无码| 国产理论剧情大片在线播放| 熟妇人妻av中文字幕老熟妇| 国产精品毛片va一区二区三区| 强被迫伦姧惨叫人妻系列| 中国熟妇内谢69xxxxx| 日韩精品久久久久久免费| 丰满人妻被中出中文字幕| 欧美人与禽猛交狂配| 国产成人剧情av麻豆果冻| 国产精品视频免费一区二区| 色拍拍欧美视频在线看| 忘忧草社区中文字幕www| 国产免费又色又爽又黄软件| 国产乱人伦偷精精品视频| 色欲色香天天天综合无码www| 天天综合亚洲色在线精品| 涩里番网污站| 欧美日韩亚洲中文字幕一区二区三区 | 欧美野性肉体狂欢大派对| 国产午夜视频在线观看| 直接观看黄网站免费视频| 国产亚洲精品合集久久久久| 日本高清视频wwww色| 亚洲国产精品无码久久久久高潮| 亚洲成a∧人片在线观看无码| 亚洲精品无码鲁网中文电影| 欧美性猛交xxxx免费看蜜桃|