在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EBF3 Antibody

  • 中文名稱:
    EBF3兔多克隆抗體
  • 貨號(hào):
    CSB-PA880977LA01HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: Colo320 whole cell lysate, A549 whole cell lysate
      All lanes: EBF3 antibody at 5.6μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 65, 61 kDa
      Observed band size: 65 kDa
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) EBF3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    EBF3
  • 別名:
    COE 3 antibody; COE3 antibody; COE3_HUMAN antibody; Early B cell factor 3 antibody; Early B-cell factor 3 antibody; EBF 3 antibody; EBF-3 antibody; EBF3 antibody; O/E 2 antibody; O/E-2 antibody; O/E2 antibody; OE 2 antibody; OE-2 antibody; OE2 antibody; Olf 1/EBF like 2 antibody; Olf-1/EBF-like 2 antibody; Transcription factor COE3 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Transcription factor COE3 protein (416-530AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated

    本頁(yè)面中的產(chǎn)品,EBF3 Antibody (CSB-PA880977LA01HU),的標(biāo)記方式是Non-conjugated。對(duì)于EBF3 Antibody,我們還提供其他標(biāo)記。見(jiàn)下表:

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA880977LB01HU EBF3 Antibody, HRP conjugated ELISA
    FITC CSB-PA880977LC01HU EBF3 Antibody, FITC conjugated
    Biotin CSB-PA880977LD01HU EBF3 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Transcriptional activator. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.
  • 基因功能參考文獻(xiàn):
    1. Data show that early B-cell factor 3 (EBF3) was identified as the direct downstream target gene of miR-23b-3p. PMID: 29750239
    2. Associations of Pulmonary Fibrosis with Peripheral Blood Th1/Th2 Cell Imbalance and EBF3 Gene Methylation in Uygur Pigeon Breeder's Lung Patients. PMID: 29913442
    3. Results found that hypermethylation of the EBF3 promoter was associated with increased EBF3 mRNA levels in metastatic melanomas and subsequent inhibition of DNA methylation reduced EBF3 expression, suggesting that EBF3 promoter hypermethylation may be a candidate epigenetic driver of metastasis. PMID: 28030832
    4. In 11 affected individuals from 11 unrelated families, we identified de novo variants in EBF3 as potentially causative for the neurodevelopmental phenotype. The variants include one nonsense, two frameshift deletions, one splice, and three missense variants. There are three de novo missense variants, (p.(Lys64Thr), p.(His157Gln), and p.(Arg209Gln), which are all in the COE1 DNA-binding domain. PMID: 29162653
    5. EBF3, a transcription factor previously unknown to be associated with human disease, is important for brain and other organ development and warrants further investigation PMID: 28017370
    6. findings indicate that mutations in EBF3 cause a genetic neurodevelopmental syndrome and suggest that loss of EBF3 function might mediate a subset of neurologic phenotypes shared by ARX-related disorders, including intellectual disability, abnormal genitalia, and structural CNS malformations PMID: 28017372
    7. findings demonstrate that variants disrupting EBF3-mediated transcriptional regulation cause intellectual disability and developmental delay and are present in approximately 0.1% of individuals with unexplained neurodevelopmental disorders PMID: 28017373
    8. Early B-cell factor 3 (EBF3) is a novel tumor suppressor gene with promoter hypermethylation in pediatric acute myeloid leukemia PMID: 25609158
    9. EBF3 tumor suppressor is epigenetically silenced and that it serves as an independent prognostic marker in gastric carcinoma. PMID: 21387304
    10. Results verify IRX1, EBF3, SLC5A8, SEPT9, and FUSSEL18 as valid methylation markers in two separate sets of HNSCC specimens; also preliminarily show a trend between HPV16 positivity and target gene hypermethylation of IRX1, EBF3, SLC5A8, and SEPT9. PMID: 20029986
    11. Findings suggested that the transfection of EBF3 gene into HepG2 induced the cell proliferation from G1 phase to G2 phase by increasing the number of cells. PMID: 18845077
    12. Expression of EBF3 resulted in cell cycle arrest and apoptosis. EBF3 regulates a transcriptional program underlying a putative tumor suppression pathway. PMID: 17018599
    13. Frequent methylation of EBF3 gene is associated with head and neck squamous cell carcinoma PMID: 18559491

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Hypotonia, ataxia, and delayed development syndrome (HADDS)
  • 亞細(xì)胞定位:
    Nucleus.
  • 蛋白家族:
    COE family
  • 組織特異性:
    Expressed in brain.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 19087

    OMIM: 607407

    KEGG: hsa:253738

    UniGene: Hs.591374



主站蜘蛛池模板: 永久黄网站色视频免费看| аⅴ天堂中文在线网官网| 欧洲美熟女乱又伦av影片| 国产成人啪精品视频免费网站软件 | 国产av国片精品| 一本大道无码人妻精品专区| 亚洲一区二区三区国产精华液| 无码人妻精品一区二区三区久久久| 成人亚洲a片v一区二区三区蜜臀| 草草影院精品一区二区三区 | 亚洲成av人片无码迅雷下载| 亚洲日本va中文字幕久久| 熟女体下毛毛黑森林| 日本牲交大片免费观看| 久久国产福利一区二区| 最新国产精品久久精品| 爱情岛论坛网亚洲品质| 国产亚洲精品字幕在线观看| 亚洲日韩乱码久久久久久| 久久777国产线看观看精品| 18禁勿入午夜网站入口| 日本伦奷在线播放| 无码一区二区三区av在线播放 | 日韩 无码 偷拍 中文字幕| 久久九九兔免费精品6| 国产成人愉拍免费视频| 伊人久久大香线蕉av成人| 久久人人爽人人爽人人片av不| 曰曰摸夜夜添夜夜添高潮出水| 美女张开腿黄网站免费下载| 午夜好爽好舒服免费视频| 国产亚洲精品久久久999蜜臀| 亚洲日本在线电影| 无码人妻精品一区二区三区66| 国产极品精品自在线| 久久久噜噜噜久久熟女色| 久久性色av亚洲电影| 久久综合给合综合久久| 日本黄页网站免费观看| 亚洲 欧美 另类 综合 日韩| 午夜福利国产成人无码gif动图|