在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DPH1 Antibody, Biotin conjugated

DPH1 Antibody, Biotin conjugated

  • 中文名稱：
    DPH1兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA871625LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) DPH1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Candidate tumor suppressor in ovarian cancer 1 antibody; Diphthamide biosynthesis protein 1 antibody; Diphthamide biosynthesis protein 2 homolog like 1 antibody; Diphthamide biosynthesis protein 2 homolog-like 1 antibody; Diphthamide biosynthesis protein 2 like antibody; Diphthamide biosynthesis protein 2-like antibody; Diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces) like 1 antibody; Diptheria toxin resistance protein required for diphthamide biosynthesis like 1 antibody; DPH like 1 (S. cerevisiae) antibody; DPH like 1 antibody; DPH-like 1 antibody; DPH1 antibody; DPH1 homolog (S. cerevisiae) antibody; DPH1 homolog antibody; DPH1_HUMAN antibody; DPH2 like 1 antibody; DPH2-like 1 antibody; DPH2L antibody; DPH2L1 antibody; FLJ33211 antibody; HsDph1 antibody; Ovarian cancer associated gene 1 antibody; Ovarian cancer associated gene 1 protein antibody; Ovarian cancer-associated gene 1 protein antibody; Ovarian tumor suppressor candidate 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 protein (192-318AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2). When overexpressed, suppresses colony formation ability and growth rate of ovarian cancer cells. Acts also as a tumor suppressor in lung and breast cancers. Plays a role in embryonic growth, organogenesis and postnatal survival.
  • 基因功能參考文獻：
    1. novel homozygous DPH1 mutation causes intellectual disability and unique craniofacial features PMID: 29410513
    2. We used WES to identify novel compound heterozygous mutations in DPH1 (c.289delG, p.Glu97Lysfs*8 and c.491T>C, p.Leu164Pro) in a patient from a nonconsanguineous family presenting with intellectual disability, a short stature, craniofacial abnormalities, and external genital abnormalities. PMID: 29362492
    3. DPH1 functions as an oncogene in CRC and can be negatively modulated by miR-218-5p to promote CRC tumourigenesis. PMID: 29145210
    4. Results identified a second homozygous missense variant in DPH1, seen in four members of a founder population, and associated with autosomal recessive intellectual disability with short stature, craniofacial, and ectodermal anomalies. PMID: 26220823
    5. Methylation of the DPH1 promoter causes immunotoxin resistance in acute lymphoblastic leukemia. PMID: 24070652
    6. OVCA1 could inhibit the proliferation of ovarian cancer cells by p16/cyclin D1 pathway, but not by NF-kappaB PMID: 21487939

    顯示更多

    收起更多

  • 相關疾病：
    Developmental delay with short stature, dysmorphic features, and sparse hair (DEDSSH)
  • 亞細胞定位：
    Nucleus. Cytoplasm. Note=Punctate, primarily perinuclear localization.
  • 蛋白家族：
    DPH1/DPH2 family, DPH1 subfamily
  • 組織特異性：
    Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, mammary gland, colon, small intestine, testis and ovary. Reduced expression in primary breast and ovarian tumors.
  • 數據庫鏈接：

    HGNC: 3003

    OMIM: 603527

    KEGG: hsa:1801

    STRING: 9606.ENSP00000263083

    UniGene: Hs.513856



主站蜘蛛池模板： 亚洲综合色自拍一区| 久久久久久久久毛片精品| 毛多水多www偷窥小便| 欧美mv日韩mv国产网站app| 国产 高潮 抽搐 正在播放| 国产精品久久久久久| 8av国产精品爽爽ⅴa在线观看| 精品无人区码一码二码三码区别 | 又粗又大又硬毛片免费看| 国产黄在线观看免费观看不卡| 国产精品久久人妻互换| 亚洲熟妇无码另类久久久| 国产成a人亚洲精品无码樱花| 野外少妇被弄到喷水在线观看| 亚洲乱码中文论理电影| 免免费国产aaaaa片| 亚洲爆乳大丰满无码专区| 日本午夜免费啪视频在线| 日韩亚洲中字无码一区二区三区| 欧美肥臀大屁股magnet| 农村老熟妇乱子伦视频| 国产精品久久久久久亚洲影视内衣 | 国内精品久久久久影院嫩草| 动漫精品专区一区二区三区| 色婷婷六月亚洲综合香蕉| 野外少妇愉情中文字幕| 久久精品中文无码资源站| 中文在线а天堂中文在线新版| 国产精品免费视频网站| 老鸭窝视频在线观看| 亚洲性线免费观看视频成熟| 99热国产这里只有精品9| 日韩欧美群交p内射捆绑| 国产真实露脸乱子伦| 欧美真人做爰在线观看| 亚洲欧洲日产国码无码久久99| 欧美国产日韩a在线观看| 久久青草成人综合网站| 久久久精品人妻一区二区三区四 | 和岳每晚弄的高潮嗷嗷叫视频| 奶真大水真多小荡货av|