在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DOK3 Antibody

DOK3 Antibody

  • 中文名稱：
    DOK3兔多克隆抗體
  • 貨號：
    CSB-PA338014
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA338014(DOK3 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human notum skin cancer tissue, Primary antibody: CSB-PA338014(DOK3 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    DOK3
  • 別名：
    Docking protein 3 antibody; DOK 3 antibody; DOK Like Protein antibody; Dok3 antibody; DOK3_HUMAN antibody; DOKL Pending antibody; Downstream of tyrosine kinase 3 antibody; p62 DOK Like Protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Fusion protein of Human DOK3
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function.
  • 基因功能參考文獻(xiàn)：
    1. Mutations in DOK3 gene is associated with prostate cancer PMID: 26585945
    2. DOK2 and DOK3 expression was significantly reduced in HTLV-1-infected T cells. PMID: 27265473
    3. The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters PMID: 23223229
    4. absence of DOK3 increases LPS signaling, contributing to LPS-induced tolerance. Thus, DOK3 plays a role in TLR signaling during both naive and endotoxin-induced tolerant conditions PMID: 22761938
    5. Identification of DOK genes as lung tumor suppressors. PMID: 20139980
    6. The novel platelet adapter Dok-3 is tyrosine phosphorylated in an Src kinase-independent manner downstream of alphaIIbbeta3 in human platelets, leading to an interaction with Grb2 and SHIP-1. PMID: 19682241
    7. findings indicate that Dok-3 sequesters Grb2 from Shc and inhibits the Ras-Erk pathway downstream of PTKs PMID: 16436051

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    DOK family, Type A subfamily
  • 組織特異性：
    Expressed in spleen.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24583

    OMIM: 611435

    KEGG: hsa:79930

    STRING: 9606.ENSP00000349727

    UniGene: Hs.720849



主站蜘蛛池模板： 国产精品videossex国产高清 | 手机国产乱子伦精品视频| 国产精品无码嫩草地址更新| 人妻少妇精品中文字幕av蜜桃| 波多野结衣 黑人| 精品国产乱码久久久久乱码| 9l国产精品久久久久麻豆| 成人国产精品秘片多多| 亚洲国产av无码精品| 欧美国产日产一区二区| 97人妻无码专区| 国产交换配偶在线视频| 色橹橹欧美在线观看视频高清| 亚欧美日韩香蕉在线播放视频| 久久久精品妇女99| 久久精品www人人做人人爽| 久久精品九九热无码免贵| 久久久久88色偷偷| 国产精品尹人在线观看| 大尺度无遮挡激烈床震网站| 国产精品水嫩水嫩| 日本特黄特色特爽大片| 国产美女精品自在线拍免费| 国产在线观看www污污污| 精品国产天线2019| 亚洲欧美一区二区成人片| 看国产黄大片在线观看| 精品久久久久久久国产潘金莲| 亚洲人成中文字幕在线观看 | 久久99精品国产麻豆宅宅| 99久久久无码国产精品古装| 国产av影片麻豆精品传媒| 久久av无码精品人妻系列试探| 亚洲欧美丝袜精品久久 | 香港曰本韩国三级网站| 日本在线视频www鲁啊鲁| 一二三四在线观看免费视频 | 国产成人午夜福利在线观看| 999久久久精品国产消防器材| 精品久久久久久中文字幕大豆网| 欧美又大又硬又粗bbbbb|