在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DOK3 Antibody

DOK3 Antibody

  • 中文名稱：
    DOK3兔多克隆抗體
  • 貨號：
    CSB-PA002182
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HepG2 cells using Dok-3 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    DOK3
  • 別名：
    Docking protein 3 antibody; DOK 3 antibody; DOK Like Protein antibody; Dok3 antibody; DOK3_HUMAN antibody; DOKL Pending antibody; Downstream of tyrosine kinase 3 antibody; p62 DOK Like Protein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Dok-3.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function.
  • 基因功能參考文獻：
    1. Mutations in DOK3 gene is associated with prostate cancer PMID: 26585945
    2. DOK2 and DOK3 expression was significantly reduced in HTLV-1-infected T cells. PMID: 27265473
    3. The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters PMID: 23223229
    4. absence of DOK3 increases LPS signaling, contributing to LPS-induced tolerance. Thus, DOK3 plays a role in TLR signaling during both naive and endotoxin-induced tolerant conditions PMID: 22761938
    5. Identification of DOK genes as lung tumor suppressors. PMID: 20139980
    6. The novel platelet adapter Dok-3 is tyrosine phosphorylated in an Src kinase-independent manner downstream of alphaIIbbeta3 in human platelets, leading to an interaction with Grb2 and SHIP-1. PMID: 19682241
    7. findings indicate that Dok-3 sequesters Grb2 from Shc and inhibits the Ras-Erk pathway downstream of PTKs PMID: 16436051

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    DOK family, Type A subfamily
  • 組織特異性：
    Expressed in spleen.
  • 數據庫鏈接：

    HGNC: 24583

    OMIM: 611435

    KEGG: hsa:79930

    STRING: 9606.ENSP00000349727

    UniGene: Hs.720849



主站蜘蛛池模板： 国产免费又黄又爽又色毛| 麻豆亚洲一区| 亚洲精品一区二区三区不卡| 无码国产69精品久久久久同性| 国产精品黄页免费高清在线观看 | 欧美日韩人人模人人爽人人喊| 人与人性恔配视频免费| 亚洲精品一区二区精华液| 人妻少妇熟女javhd| 国产日产人妻精品精品| 国内精品伊人久久久久777 | 精品人妻系列无码人妻免费视频| 亚洲日韩看片成人无码| 蜜臀少妇人妻在线| 国产三级精品三级在线观看| 夜夜影院未满十八勿进| www国产内插视频| 四虎成人欧美精品在永久在线| 亚洲欧洲无码av一区二区三区| 老色鬼在线精品视频| 香港三日本8a三级少妇三级99| 欧美 国产日韩 综合在线| 夜夜澡天天碰人人爱av| 久久久中日ab精品综合| 亚洲成av人无码综合在线观看 | 亚洲大尺度无码无码专线一区| 黑人巨茎大战欧美白妇免费| 国产精品三级av及在线观看| 无码丰满熟妇bbbbxxx| 国产成人拍精品视频午夜网站| 日本欧美大码a在线观看| 国产女人喷潮视频免费| 强 暴 疼 哭 处 女 身子视频| 中文无码乱人伦中文视频在线| 最近免费中文字幕大全免费版视频| 综合久久久久6亚洲综合| 爽到高潮无码视频在线观看| 久久人妻av一区二区软件| 久久久久国产一区二区| 日韩av毛片无码免费| 亚洲国产欧美在线人成app|