在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DCTN2 Antibody

DCTN2 Antibody

  • 中文名稱：
    DCTN2兔多克隆抗體
  • 貨號：
    CSB-PA108423
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA108423(DCTN2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA108423(DCTN2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: 293T cells, mouse brain tissue, Primary antibody: CSB-PA108423(DCTN2 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    DCTN2
  • 別名：
    50 kD dynein associated polypeptide antibody; 50 kDa dynein associated polypeptide antibody; 50 kDa dynein-associated polypeptide antibody; DCTN-50 antibody; DCTN2 antibody; DCTN2_HUMAN antibody; DCTN50 antibody; dynactin 2 (p50) antibody; dynactin 2 antibody; dynactin complex 50 kD subunit antibody; Dynactin complex 50 kDa subunit antibody; Dynactin subunit 2 antibody; DYNAMITIN antibody; p50 dynamitin antibody; RBP50 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human DCTN2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    WB 1:200-1:1000
    IHC 1:100-1:300
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
  • 基因功能參考文獻：
    1. This is the first time a haplotype on chromosome 12 containing sequence variants in the genes DCTN2, DNAH10, LRIG3, and MYO1A has been linked to an inherited neuropathy in humans. PMID: 26517670
    2. dynamitin is involved in the regulation of Nav1.5 cell-surface density PMID: 25088759
    3. the determinants of p50/DM required for self-oligomerization of the protein and for interactions with other subunits of the dynactin complex PMID: 20463029
    4. Altered levels of Cep135 and p50 by RNAi and protein overexpression caused the release of endogenous partner molecules from centrosomes. PMID: 14983524
    5. the Sec23p component of the COPII complex directly interacts with the dynactin complex through the carboxy-terminal cargo-binding domain of p150(Glued). PMID: 15580264
    6. DCTN2 is required in the earliest stages of peroxisome biogenesis. PMID: 15813749
    7. study does not support a major role for DCTN2 overexpression in carcinogenesis PMID: 16369996
    8. Data show how dynamitin's different structural domains contribute to its ability to self-associate, interact with dynactin and assemble into a complex with its close binding partner, p24. PMID: 18182012
    9. The interaction between ZW10 and dynamitin showed that the N-terminal region of ZW10 is the major binding site for dynamitin and, like full-length ZW10, could move along microtubules to the centrosomal area in a dynein-dynactin-dependent manner. PMID: 18782227

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Membrane; Peripheral membrane protein.
  • 蛋白家族：
    Dynactin subunit 2 family
  • 數據庫鏈接：

    HGNC: 2712

    OMIM: 607376

    KEGG: hsa:10540

    STRING: 9606.ENSP00000408910

    UniGene: Hs.289123



主站蜘蛛池模板： 又色又爽又黄的视频日本| 婷婷五月综合激情中文字幕 | 久久婷婷人人澡人人爽人人喊 | 国产女主播白浆在线观看| 色情久久久av熟女人妻网站| 成年午夜精品久久久精品| 麻豆国产成人av在线播放欲色| 亚洲国产中文在线视频| 日本精品人妻无码77777| 久无码久无码av无码| 欧美成va视频网站| 九九热久久只有精品2| 狠狠噜天天噜日日噜视频麻豆| 色窝窝无码一区二区三区色欲| 久久亚洲私人国产精品va| 亚洲色大网站www永久网站| 2019精品国自产拍在线不卡| 欧洲女人牲交视频免费| 苍井空浴缸大战猛男120分钟| 亚洲国产精品久久亚洲精品| 午夜福利无遮挡十八禁视频| 中文字幕一区日韩精品| 特级毛片a片久久久久久| 熟妇好大好深好满好爽| 波多野42部无码喷潮在线| 欧洲精品va无码一区二区三区| 2020精品国产a不卡片| 国产伦精品一区二区三区免费| 亚洲男人的天堂网站| 国产精品久久久久久无码五月| 亚洲欧洲日产国码无码| 中国女人做爰视频| 高潮喷水无码av亚洲| 日韩a人毛片精品无人区乱码| 国产无套精品一区二区| 人妻无码中文专区久久app| 无码不卡中文字幕av| 最近更新中文字幕免费大全| 爆乳熟妇一区二区三区霸乳| 国产清纯白嫩初高生在线观看| 亚洲成av 人片在线观看无码|