在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DCTN2 Antibody

  • 中文名稱:
    DCTN2兔多克隆抗體
  • 貨號:
    CSB-PA002220
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of A549 cells using Dynactin 2 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    DCTN2
  • 別名:
    50 kD dynein associated polypeptide antibody; 50 kDa dynein associated polypeptide antibody; 50 kDa dynein-associated polypeptide antibody; DCTN-50 antibody; DCTN2 antibody; DCTN2_HUMAN antibody; DCTN50 antibody; dynactin 2 (p50) antibody; dynactin 2 antibody; dynactin complex 50 kD subunit antibody; Dynactin complex 50 kDa subunit antibody; Dynactin subunit 2 antibody; DYNAMITIN antibody; p50 dynamitin antibody; RBP50 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the C-terminal region of Human Dynactin 2.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
  • 基因功能參考文獻:
    1. This is the first time a haplotype on chromosome 12 containing sequence variants in the genes DCTN2, DNAH10, LRIG3, and MYO1A has been linked to an inherited neuropathy in humans. PMID: 26517670
    2. dynamitin is involved in the regulation of Nav1.5 cell-surface density PMID: 25088759
    3. the determinants of p50/DM required for self-oligomerization of the protein and for interactions with other subunits of the dynactin complex PMID: 20463029
    4. Altered levels of Cep135 and p50 by RNAi and protein overexpression caused the release of endogenous partner molecules from centrosomes. PMID: 14983524
    5. the Sec23p component of the COPII complex directly interacts with the dynactin complex through the carboxy-terminal cargo-binding domain of p150(Glued). PMID: 15580264
    6. DCTN2 is required in the earliest stages of peroxisome biogenesis. PMID: 15813749
    7. study does not support a major role for DCTN2 overexpression in carcinogenesis PMID: 16369996
    8. Data show how dynamitin's different structural domains contribute to its ability to self-associate, interact with dynactin and assemble into a complex with its close binding partner, p24. PMID: 18182012
    9. The interaction between ZW10 and dynamitin showed that the N-terminal region of ZW10 is the major binding site for dynamitin and, like full-length ZW10, could move along microtubules to the centrosomal area in a dynein-dynactin-dependent manner. PMID: 18782227

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Membrane; Peripheral membrane protein.
  • 蛋白家族:
    Dynactin subunit 2 family
  • 數據庫鏈接:

    HGNC: 2712

    OMIM: 607376

    KEGG: hsa:10540

    STRING: 9606.ENSP00000408910

    UniGene: Hs.289123



主站蜘蛛池模板: 国产女人高潮叫床视频| 精品 在线 视频 亚洲| 国产成人精品三级麻豆| 国产精品无码免费专区午夜| 免费人成网站在线观看不卡| 性欧美videofree高清精品| 五月综合激情婷婷六月色窝| 99re6在线视频精品免费下载| 中文精品久久久久人妻| 欧洲精品无码一区二区三区在线播放 | 大香线蕉伊人精品超碰| 少妇人妻综合久久中文| 男人添女人囗交做爰视频| 欧美孕妇变态重口另类| 色欲天天婬色婬香综合网完整| 久久66热人妻偷产精品9| 无限看片在线版免费视频大全| 久久久久人妻一区精品色欧美| 制服视频在线一区二区| 成人网站www污污污网站| 色天使久久综合给合久久97色| 精品欧美一区二区三区久久久| 曰本女人与公拘交酡免费视频| 精品久久国产综合婷婷五月| 亚洲精品1卡2卡三卡23卡| 久久99国产亚洲高清观看首页| 成人看片黄a免费看在线| 国产内射一区亚洲| 国产在线精品一区二区中文| 性欧美激情aa片在线播放| 人妻avav中文系列久久| 久久人搡人人玩人妻精品| 婷婷综合另类小说色区| 在线亚洲日产一区二区| 亚洲乱码中文字幕小综合| 人妻去按摩店被黑人按中出 | 国产日韩在线观看不卡顿| 亚洲熟女乱色综合亚洲小说| 久久99精品国产麻豆蜜芽| 国产亚洲中文字幕在线制服| 男女后进式猛烈xx00动态图片 |