在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DCT Antibody

  • 中文名稱:
    DCT兔多克隆抗體
  • 貨號:
    CSB-PA845534
  • 規格:
    ¥1090
  • 圖片:
    • Western blot analysis of HELA A549 Cell Lysate, antibody was diluted at 1:1000. Secondary antibody was diluted at 1:20000
    • Immunohistochemical analysis of paraffin-embedded human-breast-cancer, antibody was diluted at 1:200
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    L dopachrome tautomerase antibody; DCT antibody; Dopachrome delta isomerase antibody; Dopachrome tautomerase antibody; Dopachrome tautomerase dopachrome delta isomerase; tyrosine related protein 2 antibody; DT antibody; EC 5.3.3.12 antibody; L dopachrome Delta isomerase antibody; L-dopachrome Delta-isomerase antibody; L-dopachrome tautomerase antibody; TRP 2 antibody; TRP-2 antibody; TRP2 antibody; Tyrosinase related protein 2 antibody; Tyrosinase-related protein 2 antibody; TYRP2 antibody; TYRP2_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthetic peptide from Human protein at AA range: 1268-1341
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 純化方式:
    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:50-1:300
    ELISA 1:5000-1:20000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA).
  • 基因功能參考文獻:
    1. High DCT expression is associated with progressive multiple sclerosis. PMID: 28923927
    2. High DCT expression is associated with HPV16 Infection. PMID: 28095444
    3. Data indicate that the caveolin-1 (CAV1) control on dopachrome tautomerase (DCT) gene expression, DCT post-translational processing, and subcellular distribution is cell phenotype-dependent. PMID: 27053106
    4. The effect of DCT on UVR DNA damage responses and survival pathways in melanocytes was examined by knockdown experiments using melanoma cells, neonatal melanoblasts in monoculture and in co-culture with keratinocytes. PMID: 25346513
    5. Report dopachrome tautomerase expression in mealanocytic tumors. PMID: 24709887
    6. The results suggested that the miRNAs may be involved in MITF regulation of TYR, TYRP1 and TYRP2, which provides a new clue for understanding the role of miRNAs in melanocyte dysfunctional disease. PMID: 22898827
    7. Data suggest that macrophage migration inhibitory factor (MIF) and d-dopachrome tautomerase (d-DT) act cooperatively to inhibit steady-state phosphorylation and activation of AMPK in LKB1 wild type and LKB1 mutant non-small cell lung carcinomas cells. PMID: 22988252
    8. human TRP2 counteracts apoptotic cell death induction, possibly by means of its L-dopachrome tautomerase activity, and negatively affects the p53 pathway PMID: 20520707
    9. Trp2 SNP2 allele is a risk factor for the development and severity of degenerative disc disease in a Chinese Han population. PMID: 20356546
    10. Data suggest that OTX2 may regulate retinal pigment epithelium (RPE)-specific target genes, such as DOPAchrome tautomerase (DCT), thereby maintaining the homeostasis of RPE. PMID: 12559959
    11. Because TRP-2(181-190) overlaps with the known HLA-A*0201-presented epitope TRP-2(180-188), an 11mer peptide encompassing both epitopes might be of specific value for vaccination of a broad population of melanoma patients. PMID: 15856458
    12. Transgenic Dct regulates neural progenitor cell proliferation in a mouse model. PMID: 16857183
    13. No genetic susceptibility or increased risk attributed to the tyrosinase gene family in Vogt-Koyanagi-Harada disease in Japanese. PMID: 17200659
    14. Anemonin, an active compound of C. crassifolia, inhibits melanin synthesis by inhibiting the transcription of the genes encoding TYR, TRP1, and TRP2. PMID: 17766092
    15. we studied a possible role of dopachrome tautomerase in the oxidative stress response in the amelanotic WM35 melanoma cell line. PMID: 18206123
    16. We observe strong evidence for positive selection for DCT in Asians PMID: 18312627
    17. Tyrosinase-, gp100-, or TRP-2-specific CD8(+) T cells could not be identified in the peripheral blood of individuals with vitiligo [TRP-2]. PMID: 18337837
    18. TRP-2 acts on quinone metabolites other than DOPAchrome, e.g., in the catecholamine pathway, and limits their deleterious effects. PMID: 18674612
    19. tyrosinase-related protein 2 (TRP-2) transcript is not detected in the peripheral blood mononuclear cells (PBMC) of vitiligo patients PMID: 19284502
    20. Expression profiling demonstrated that the DCT-expressing cell population expressed adrenergic and muscarinic receptors and displayed transcriptional profiles distinct from dermal melanocytes PMID: 19855129

    顯示更多

    收起更多

  • 亞細胞定位:
    Melanosome membrane; Single-pass type I membrane protein. Melanosome.
  • 蛋白家族:
    Tyrosinase family
  • 數據庫鏈接:

    HGNC: 2709

    OMIM: 191275

    KEGG: hsa:1638

    UniGene: Hs.301865



主站蜘蛛池模板: 久久se精品一区二区三区| 狂野av人人澡人人添| 巨大乳做爰视频在线看| 四虎www永久在线精品| 亚洲人ⅴsaⅴ国产精品| 四虎影成人精品a片| 亚洲国产av玩弄放荡人妇| 国产乱子伦精品免费视频| 中文字幕无线码中文字幕免费| 国产成人精品亚洲午夜麻豆| 成人午夜看黄在线尤物成人 | 国产v亚洲v天堂a无码99| 精品国产三级a∨在线欧美| 中文字幕无线码| 色综合天天无码网站| 97国产一区二区三区四区久久| 中文字幕日韩人妻在线视频| 日本一二三区视频在线| 国产传媒麻豆剧精品av国产| 亚洲国产欧美在线人成aaaa| 久久久亚洲欧洲日产国码是av| 少妇的丰满3中文字幕| 免费国产精品视频在线| 精品国产亚洲一区二区三区在线观看 | 无码日韩精品一区二区三区免费| 久久99国产亚洲高清观看首页| 国产边摸边吃奶边做爽视频| 国产成人免费高清直播| 三上悠亚ssⅰn939无码播放| 小泽玛莉亚一区二区视频在线| 国产又粗又猛又爽的视频a片 | 久久久久波多野结衣高潮| 日韩乱码人妻无码系列中文字幕| 中文字幕久精品免费视频| 精品香蕉99久久久久网站| 五级黄高潮片90分钟视频| 亚洲制服 视频在线观看| 中文字幕久久精品波多野结百度 | 无码国产精品一区二区免费虚拟vr| 亚洲欧洲自拍拍偷综合| 最近日本免费观看高清视频|