在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DCT Antibody

  • 中文名稱:
    DCT兔多克隆抗體
  • 貨號:
    CSB-PA004336
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of Hela cells using TRP2 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    L dopachrome tautomerase antibody; DCT antibody; Dopachrome delta isomerase antibody; Dopachrome tautomerase antibody; Dopachrome tautomerase dopachrome delta isomerase; tyrosine related protein 2 antibody; DT antibody; EC 5.3.3.12 antibody; L dopachrome Delta isomerase antibody; L-dopachrome Delta-isomerase antibody; L-dopachrome tautomerase antibody; TRP 2 antibody; TRP-2 antibody; TRP2 antibody; Tyrosinase related protein 2 antibody; Tyrosinase-related protein 2 antibody; TYRP2 antibody; TYRP2_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human TRP2.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:40000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA).
  • 基因功能參考文獻:
    1. High DCT expression is associated with progressive multiple sclerosis. PMID: 28923927
    2. High DCT expression is associated with HPV16 Infection. PMID: 28095444
    3. Data indicate that the caveolin-1 (CAV1) control on dopachrome tautomerase (DCT) gene expression, DCT post-translational processing, and subcellular distribution is cell phenotype-dependent. PMID: 27053106
    4. The effect of DCT on UVR DNA damage responses and survival pathways in melanocytes was examined by knockdown experiments using melanoma cells, neonatal melanoblasts in monoculture and in co-culture with keratinocytes. PMID: 25346513
    5. Report dopachrome tautomerase expression in mealanocytic tumors. PMID: 24709887
    6. The results suggested that the miRNAs may be involved in MITF regulation of TYR, TYRP1 and TYRP2, which provides a new clue for understanding the role of miRNAs in melanocyte dysfunctional disease. PMID: 22898827
    7. Data suggest that macrophage migration inhibitory factor (MIF) and d-dopachrome tautomerase (d-DT) act cooperatively to inhibit steady-state phosphorylation and activation of AMPK in LKB1 wild type and LKB1 mutant non-small cell lung carcinomas cells. PMID: 22988252
    8. human TRP2 counteracts apoptotic cell death induction, possibly by means of its L-dopachrome tautomerase activity, and negatively affects the p53 pathway PMID: 20520707
    9. Trp2 SNP2 allele is a risk factor for the development and severity of degenerative disc disease in a Chinese Han population. PMID: 20356546
    10. Data suggest that OTX2 may regulate retinal pigment epithelium (RPE)-specific target genes, such as DOPAchrome tautomerase (DCT), thereby maintaining the homeostasis of RPE. PMID: 12559959
    11. Because TRP-2(181-190) overlaps with the known HLA-A*0201-presented epitope TRP-2(180-188), an 11mer peptide encompassing both epitopes might be of specific value for vaccination of a broad population of melanoma patients. PMID: 15856458
    12. Transgenic Dct regulates neural progenitor cell proliferation in a mouse model. PMID: 16857183
    13. No genetic susceptibility or increased risk attributed to the tyrosinase gene family in Vogt-Koyanagi-Harada disease in Japanese. PMID: 17200659
    14. Anemonin, an active compound of C. crassifolia, inhibits melanin synthesis by inhibiting the transcription of the genes encoding TYR, TRP1, and TRP2. PMID: 17766092
    15. we studied a possible role of dopachrome tautomerase in the oxidative stress response in the amelanotic WM35 melanoma cell line. PMID: 18206123
    16. We observe strong evidence for positive selection for DCT in Asians PMID: 18312627
    17. Tyrosinase-, gp100-, or TRP-2-specific CD8(+) T cells could not be identified in the peripheral blood of individuals with vitiligo [TRP-2]. PMID: 18337837
    18. TRP-2 acts on quinone metabolites other than DOPAchrome, e.g., in the catecholamine pathway, and limits their deleterious effects. PMID: 18674612
    19. tyrosinase-related protein 2 (TRP-2) transcript is not detected in the peripheral blood mononuclear cells (PBMC) of vitiligo patients PMID: 19284502
    20. Expression profiling demonstrated that the DCT-expressing cell population expressed adrenergic and muscarinic receptors and displayed transcriptional profiles distinct from dermal melanocytes PMID: 19855129

    顯示更多

    收起更多

  • 亞細胞定位:
    Melanosome membrane; Single-pass type I membrane protein. Melanosome.
  • 蛋白家族:
    Tyrosinase family
  • 數據庫鏈接:

    HGNC: 2709

    OMIM: 191275

    KEGG: hsa:1638

    UniGene: Hs.301865



主站蜘蛛池模板: 中文字幕人妻被公上司喝醉506| 成熟女人牲交片免费观看视频| 欧美大成色www永久网站婷| 国产精品免费久久久久影院| 亚洲va久久久噜噜噜久久狠狠| 色猫咪av在线观看| 狠狠色噜噜狠狠狠狠888奇禾| 亚洲国产99精品国自产拍| 欧美大片欧美激情性色a∨在线| 爱久久av一区二区三区| 成人伊人精品色xxxx视频| 国产日产欧产精品精品 | 亚洲欧洲日产韩国无码| 五月色婷婷丁香无码三级| 亚洲а∨天堂男人色无码| 无码熟妇αⅴ人妻又粗又大| 国产在线精品一区二区不卡麻豆| 亚洲偷自拍国综合| 日本工口里番无遮█彩色| 五十路丰满中年熟女中出| 久久精品国产色蜜蜜麻豆| 国产日产欧产精品| 啪啪激情婷婷久久婷婷色五月| 亚洲色成人一区二区三区| 无码国内精品久久人妻| 狠狠躁夜夜躁人人爽超碰97香蕉 | 久久九九精品国产综合喷水| 亚洲国产精品成人影片久久| 久久亚洲精品中文字幕无码| 狠狠色综合7777久夜色撩人ⅰ| 亚洲精品无码mⅴ在线观看| av网站的免费观看| 国产一区二区三区无码免费| 99久久无码私人网站| 亚洲精品你懂的在线观看| 18禁黄久久久aaa片| 区二区欧美性插b在线视频网站| 久久亚洲精品高潮综合色a片| 又黄又湿免费高清视频| 亚洲精品无播放器在线播放| 婷婷五月深深久久精品|