在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DCT Antibody

  • 中文名稱:
    DCT兔多克隆抗體
  • 貨號:
    CSB-PA006562LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA006562LA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) DCT Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    L dopachrome tautomerase antibody; DCT antibody; Dopachrome delta isomerase antibody; Dopachrome tautomerase antibody; Dopachrome tautomerase dopachrome delta isomerase; tyrosine related protein 2 antibody; DT antibody; EC 5.3.3.12 antibody; L dopachrome Delta isomerase antibody; L-dopachrome Delta-isomerase antibody; L-dopachrome tautomerase antibody; TRP 2 antibody; TRP-2 antibody; TRP2 antibody; Tyrosinase related protein 2 antibody; Tyrosinase-related protein 2 antibody; TYRP2 antibody; TYRP2_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human L-dopachrome tautomerase protein (44-205AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,DCT Antibody (CSB-PA006562LA01HU),的標記方式是Non-conjugated。對于DCT Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA006562LB01HU DCT Antibody, HRP conjugated ELISA
    FITC CSB-PA006562LC01HU DCT Antibody, FITC conjugated
    Biotin CSB-PA006562LD01HU DCT Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA).
  • 基因功能參考文獻:
    1. High DCT expression is associated with progressive multiple sclerosis. PMID: 28923927
    2. High DCT expression is associated with HPV16 Infection. PMID: 28095444
    3. Data indicate that the caveolin-1 (CAV1) control on dopachrome tautomerase (DCT) gene expression, DCT post-translational processing, and subcellular distribution is cell phenotype-dependent. PMID: 27053106
    4. The effect of DCT on UVR DNA damage responses and survival pathways in melanocytes was examined by knockdown experiments using melanoma cells, neonatal melanoblasts in monoculture and in co-culture with keratinocytes. PMID: 25346513
    5. Report dopachrome tautomerase expression in mealanocytic tumors. PMID: 24709887
    6. The results suggested that the miRNAs may be involved in MITF regulation of TYR, TYRP1 and TYRP2, which provides a new clue for understanding the role of miRNAs in melanocyte dysfunctional disease. PMID: 22898827
    7. Data suggest that macrophage migration inhibitory factor (MIF) and d-dopachrome tautomerase (d-DT) act cooperatively to inhibit steady-state phosphorylation and activation of AMPK in LKB1 wild type and LKB1 mutant non-small cell lung carcinomas cells. PMID: 22988252
    8. human TRP2 counteracts apoptotic cell death induction, possibly by means of its L-dopachrome tautomerase activity, and negatively affects the p53 pathway PMID: 20520707
    9. Trp2 SNP2 allele is a risk factor for the development and severity of degenerative disc disease in a Chinese Han population. PMID: 20356546
    10. Data suggest that OTX2 may regulate retinal pigment epithelium (RPE)-specific target genes, such as DOPAchrome tautomerase (DCT), thereby maintaining the homeostasis of RPE. PMID: 12559959
    11. Because TRP-2(181-190) overlaps with the known HLA-A*0201-presented epitope TRP-2(180-188), an 11mer peptide encompassing both epitopes might be of specific value for vaccination of a broad population of melanoma patients. PMID: 15856458
    12. Transgenic Dct regulates neural progenitor cell proliferation in a mouse model. PMID: 16857183
    13. No genetic susceptibility or increased risk attributed to the tyrosinase gene family in Vogt-Koyanagi-Harada disease in Japanese. PMID: 17200659
    14. Anemonin, an active compound of C. crassifolia, inhibits melanin synthesis by inhibiting the transcription of the genes encoding TYR, TRP1, and TRP2. PMID: 17766092
    15. we studied a possible role of dopachrome tautomerase in the oxidative stress response in the amelanotic WM35 melanoma cell line. PMID: 18206123
    16. We observe strong evidence for positive selection for DCT in Asians PMID: 18312627
    17. Tyrosinase-, gp100-, or TRP-2-specific CD8(+) T cells could not be identified in the peripheral blood of individuals with vitiligo [TRP-2]. PMID: 18337837
    18. TRP-2 acts on quinone metabolites other than DOPAchrome, e.g., in the catecholamine pathway, and limits their deleterious effects. PMID: 18674612
    19. tyrosinase-related protein 2 (TRP-2) transcript is not detected in the peripheral blood mononuclear cells (PBMC) of vitiligo patients PMID: 19284502
    20. Expression profiling demonstrated that the DCT-expressing cell population expressed adrenergic and muscarinic receptors and displayed transcriptional profiles distinct from dermal melanocytes PMID: 19855129

    顯示更多

    收起更多

  • 亞細胞定位:
    Melanosome membrane; Single-pass type I membrane protein. Melanosome.
  • 蛋白家族:
    Tyrosinase family
  • 數據庫鏈接:

    HGNC: 2709

    OMIM: 191275

    KEGG: hsa:1638

    UniGene: Hs.301865



主站蜘蛛池模板: 久久成人网站亚洲综合| 拍国产乱人伦偷精品视频| 2020国产亚洲美女精品久久久| 亚洲色无码专区在线观看| 性按摩玩人妻hd中文字幕| 国产成人一区二区三区别| 色综合天天无码网站| 国内野外强奷在线视频| 国产亚洲精品精品国产亚洲综合| 欧洲熟妇色xxxx欧美老妇| 欧美性色大片在线观看| 久久996re热这里有精品 | 少妇高清精品毛片在线视频| 高大丰满欧美熟妇hd| 亚洲人亚洲人成电影网站色| 色综合久久无码五十路人妻| 久久精品2021国产| 欧洲无线码免费一区| 午夜福利理论片高清在线观看| 四虎影视成人永久免费观看视频| 蜜桃av久久久一区二区三区麻豆| 最大胆裸体人体牲交免费| 亚洲熟妇少妇任你躁在线观看无码| 国产精品香蕉在线的人| 女m羞辱调教视频网站| 亚洲精品久久久久久动漫| 少妇饥渴xxhd麻豆xxhd骆驼| 亚洲伊人丝袜精品久久| 国产乱人伦av在线a最新| 蜜桃视频在线观看免费视频网站www | 免费无码又爽又刺激一高潮| 精品无码国模私拍视频| 欧美成人精品三级网站| 国产激情大臿免费视频| 图片区小说区亚洲欧美自拍| 久久丫精品忘忧草西安产品| 99在线精品免费视频九九视| 成人无遮挡18禁免费视频| 精品无人国产偷自产在线| 天天做天天爱天天综合网| 乱子伦av无码中文字|