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DCAF6 Antibody

  • 中文名稱:
    DCAF6兔多克隆抗體
  • 貨號:
    CSB-PA203330
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA203330(DCAF6 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA203330(DCAF6 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    DCAF6
  • 別名:
    1200006M05Rik antibody; Androgen receptor complex associated protein antibody; Androgen receptor complex-associated protein antibody; ARCAP antibody; DCAF6 antibody; DCAF6_HUMAN antibody; DDB1 and CUL4 associated factor 6 antibody; DDB1- and CUL4-associated factor 6 antibody; IQ motif and WD repeat-containing protein 1 antibody; IQ motif and WD repeats 1 antibody; IQWD1 antibody; MSTP055 antibody; NRIP antibody; Nuclear receptor interaction protein antibody; RP4 745I14.1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthetic peptide of Human DCAF6
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
  • 基因功能參考文獻:
    1. High IQWD1 expression is associated with breast cancer. PMID: 24222117
    2. NRIP enhances HPV 16 gene expression via interaction with either GR or viral E2. PMID: 22177699
    3. NRIP interacts with either androgen or glucocorticoid receptors PMID: 15784617
    4. NRIP plays a feed-forward role enhancing androgen receptor (AR)-driven NRIP promoter activity via NRIP forming a complex with AR to protect AR protein from proteasome degradation. PMID: 17984071
    5. A survey results showed that ten cancer cases were revealed to express the NRIP in six malignancies, but not all of these specific tumor types consistently showed positive NRIP expression. PMID: 18673574

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  • 亞細胞定位:
    Nucleus.
  • 組織特異性:
    Highly expressed in skeletal muscle and testis. Expressed to a lesser degree in heart, prostate, and adrenal gland.
  • 數據庫鏈接:

    HGNC: 30002

    OMIM: 610494

    KEGG: hsa:55827

    STRING: 9606.ENSP00000356814

    UniGene: Hs.435741



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