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  4. DCAF6 Antibody

DCAF6 Antibody

  • 中文名稱：
    DCAF6兔多克隆抗體
  • 貨號：
    CSB-PA981190
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA981190(DCAF6 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA981190(DCAF6 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    DCAF6
  • 別名：
    1200006M05Rik antibody; Androgen receptor complex associated protein antibody; Androgen receptor complex-associated protein antibody; ARCAP antibody; DCAF6 antibody; DCAF6_HUMAN antibody; DDB1 and CUL4 associated factor 6 antibody; DDB1- and CUL4-associated factor 6 antibody; IQ motif and WD repeat-containing protein 1 antibody; IQ motif and WD repeats 1 antibody; IQWD1 antibody; MSTP055 antibody; NRIP antibody; Nuclear receptor interaction protein antibody; RP4 745I14.1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human DCAF6
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
  • 基因功能參考文獻：
    1. High IQWD1 expression is associated with breast cancer. PMID: 24222117
    2. NRIP enhances HPV 16 gene expression via interaction with either GR or viral E2. PMID: 22177699
    3. NRIP interacts with either androgen or glucocorticoid receptors PMID: 15784617
    4. NRIP plays a feed-forward role enhancing androgen receptor (AR)-driven NRIP promoter activity via NRIP forming a complex with AR to protect AR protein from proteasome degradation. PMID: 17984071
    5. A survey results showed that ten cancer cases were revealed to express the NRIP in six malignancies, but not all of these specific tumor types consistently showed positive NRIP expression. PMID: 18673574

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  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Highly expressed in skeletal muscle and testis. Expressed to a lesser degree in heart, prostate, and adrenal gland.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30002

    OMIM: 610494

    KEGG: hsa:55827

    STRING: 9606.ENSP00000356814

    UniGene: Hs.435741



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