在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CLDN11 Antibody, FITC conjugated

  • 中文名稱:
    CLDN11兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA005492LC11HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CLDN11 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    CLDN11
  • 別名:
    CLDN11; OSP; OTM; Claudin-11; Oligodendrocyte-specific protein
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Claudin-11 protein (23-82AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
  • 基因功能參考文獻:
    1. expression of claudin-11 in cutaneous squamous cell carcinoma (cSCC) cells depended on the activity of p38delta MAPK; knock-down of claudin-11 enhanced cSCC cell invasion PMID: 27992079
    2. Authors demonstrated that CLDN11 promoter hypermethylation is a frequent event in LSCC, and contributes to metastasis and progression of LSCC. PMID: 28743857
    3. The expression of claudin-11, -23 was remarkably downregulated in gastric cancer. PMID: 28350854
    4. Claudin-11 might represent the essential component of the blood-testis barrier in human. PMID: 27486954
    5. the expression of miR-99b was inversely correlated with CLDN11 levels . These findings suggest that a high level of miR-99b expression is an independent prognostic factor and correlates with poor survival of patients with Hepatocellular carcinoma (HCC) PMID: 26134929
    6. CLDN11 is an epigenetic biomarker for malignancy in dysplastic nevus and melanoma. PMID: 24999589
    7. these data suggest that cancer cells may induce CLDN11 overexpression and subsequent collective migration of peritumoral CAFs via TGF-beta secretion. PMID: 24268521
    8. The expression of claudin-11 was up regulated in gastric cancer tissue. PMID: 23919729
    9. The spatial organization of claudin-11 and connexin-43 is altered in men with primary seminiferous tubule failure. PMID: 23706332
    10. disorganization of claudin-11 expression in Sertoli cells might be one of the factors involved in the impairment of spermatogenesis. PMID: 22951003
    11. Treatment with 3-deazaneplanocin A, an inhibitor of H3K27 methyltransferase, attenuated CLDN11 induction by serum stimulation in parallel with sustained miR-1275 expression PMID: 22736761
    12. claudin-11 may have a role in preventing cancer progression and may serve as a therapeutic target in reducing metastasis PMID: 21468549
    13. late spermatogenic wave may negatively regulate claudin-11 gene activation and the subcellular localization of claudin-11 in Sertoli cells, thus altering the blood testis barrier in the human testis PMID: 20850723
    14. Claudins 11,expression in meningiomas. PMID: 20546350
    15. hypermethylation of CLDN11, leading to downregulated expression, contributes to gastric carcinogenesis by increasing cellular motility and invasiveness PMID: 19956721
    16. Contribution of the tight junction protein CLDN11 to barrier function in endothelial cells is novel and may reflect hemodynamic requirements of the corpus cavernosum. PMID: 19622796
    17. Data demonstrate that in rhesus monkeys immune responses directed at human OSP are encephalitogenic, leading to inflammatory responses throughout the central nervous system and to selective demyelination of the optic nerve. PMID: 18412169
    18. the disruption of the blood-testis barrier is related to a dysfunction of claudin-11 and not to a failure of its expression. PMID: 19241088

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Claudin family
  • 數據庫鏈接:

    HGNC: 8514

    OMIM: 601326

    KEGG: hsa:5010

    STRING: 9606.ENSP00000064724

    UniGene: Hs.31595



主站蜘蛛池模板: 少妇荡乳情欲办公室456视频| 国产一区二区三区不卡在线观看| 国产精品免费看久久久| 亚洲熟妇无码一区二区三区导航| 国产福利萌白酱精品tv一区| 无码精品人妻一区二区三区98| 综合五月激情二区视频| 亚洲精品久久久久久中文字幕| 日产日韩亚洲欧美综合下载| 欧美人妻久久精品| 国产又大又硬又粗| 亚洲永久网址在线观看| 最近中文字幕免费mv在线| 樱花草在线社区www中国| 亚洲国产精品无码久久98| 人妻洗澡被强公日日澡| 性一交一乱一伦一| 国产人成视频在线观看| 少妇挑战三个黑人惨叫4p国语| 超碰cao已满18进入离开官网| 成人网站国产在线视频内射视频| 18禁黄网站禁片免费观看| 亚洲国产精品久久久久久| 久久综合狠狠综合久久综| 97在线观看永久免费视频| 一区二区三区视频| 婷婷丁香五月六月综合激情啪| 老熟女老太婆爽| 少妇把腿扒开让我舔18| 精品久久久久久无码不卡| 色婷婷亚洲精品综合影院| 毛片免费全部播放无码| 色综合色综合久久综合频道88| 亚洲h成年动漫在线观看网站| 又白又嫩毛又多15p| 欧美深性狂猛ⅹxxx深喉| 337p亚洲日本中国大胆69| 中文字幕一区在线观看视频| 国产精品嫩草影院av| 任你躁久久精品6| 真人床震高潮全部视频免费 |