在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CLDN11 Antibody, Biotin conjugated

  • 中文名稱:
    CLDN11兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA005492LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CLDN11 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    CLDN11
  • 別名:
    CLDN11; OSP; OTM; Claudin-11; Oligodendrocyte-specific protein
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Claudin-11 protein (23-82AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
  • 基因功能參考文獻:
    1. expression of claudin-11 in cutaneous squamous cell carcinoma (cSCC) cells depended on the activity of p38delta MAPK; knock-down of claudin-11 enhanced cSCC cell invasion PMID: 27992079
    2. Authors demonstrated that CLDN11 promoter hypermethylation is a frequent event in LSCC, and contributes to metastasis and progression of LSCC. PMID: 28743857
    3. The expression of claudin-11, -23 was remarkably downregulated in gastric cancer. PMID: 28350854
    4. Claudin-11 might represent the essential component of the blood-testis barrier in human. PMID: 27486954
    5. the expression of miR-99b was inversely correlated with CLDN11 levels . These findings suggest that a high level of miR-99b expression is an independent prognostic factor and correlates with poor survival of patients with Hepatocellular carcinoma (HCC) PMID: 26134929
    6. CLDN11 is an epigenetic biomarker for malignancy in dysplastic nevus and melanoma. PMID: 24999589
    7. these data suggest that cancer cells may induce CLDN11 overexpression and subsequent collective migration of peritumoral CAFs via TGF-beta secretion. PMID: 24268521
    8. The expression of claudin-11 was up regulated in gastric cancer tissue. PMID: 23919729
    9. The spatial organization of claudin-11 and connexin-43 is altered in men with primary seminiferous tubule failure. PMID: 23706332
    10. disorganization of claudin-11 expression in Sertoli cells might be one of the factors involved in the impairment of spermatogenesis. PMID: 22951003
    11. Treatment with 3-deazaneplanocin A, an inhibitor of H3K27 methyltransferase, attenuated CLDN11 induction by serum stimulation in parallel with sustained miR-1275 expression PMID: 22736761
    12. claudin-11 may have a role in preventing cancer progression and may serve as a therapeutic target in reducing metastasis PMID: 21468549
    13. late spermatogenic wave may negatively regulate claudin-11 gene activation and the subcellular localization of claudin-11 in Sertoli cells, thus altering the blood testis barrier in the human testis PMID: 20850723
    14. Claudins 11,expression in meningiomas. PMID: 20546350
    15. hypermethylation of CLDN11, leading to downregulated expression, contributes to gastric carcinogenesis by increasing cellular motility and invasiveness PMID: 19956721
    16. Contribution of the tight junction protein CLDN11 to barrier function in endothelial cells is novel and may reflect hemodynamic requirements of the corpus cavernosum. PMID: 19622796
    17. Data demonstrate that in rhesus monkeys immune responses directed at human OSP are encephalitogenic, leading to inflammatory responses throughout the central nervous system and to selective demyelination of the optic nerve. PMID: 18412169
    18. the disruption of the blood-testis barrier is related to a dysfunction of claudin-11 and not to a failure of its expression. PMID: 19241088

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Claudin family
  • 數據庫鏈接:

    HGNC: 8514

    OMIM: 601326

    KEGG: hsa:5010

    STRING: 9606.ENSP00000064724

    UniGene: Hs.31595



主站蜘蛛池模板: 少妇做爰免费视频了| 精品国产午夜理论片不卡精品 | 国产农村妇女毛片精品久久| 欧美成人午夜免费全部完| 国产精品激情欧美可乐视频| 国产成人美女裸体片免费看| 综合亚洲综合图区网友自拍| 国产日韩一区二区三免费高清 | 国产白丝精品爽爽久久蜜臀| 丰满少妇被猛烈进入av久久| 无码孕妇孕交在线观看| 一区二区国产精品精华液| 无码av一区二区大桥久未| 久艾草在线精品视频在线观看| 熟妇高潮喷沈阳45熟妇高潮喷| 中文字幕亚洲乱码熟女在线| 免费无码黄动漫十八禁| 日本xxxx少妇高清hd| 亚洲第一无码精品立川理惠| 99精品国产一区二区| 午夜男女无遮挡拍拍视频| 国产精品久久久久久久伊一| 亚洲精品成a人在线观看| 国精品无码一区二区三区在线蜜臀| 国产午夜福利院757视频| 中文字幕乱码熟妇五十中出色欲 | 天堂在线.www天堂在线资源| 免费人成视频x8x8| 野花社区在线www日本| 亚洲 小说 欧美 另类 社区| 国产精品国产三级国快看| 色翁荡息又大又硬又粗又爽| 久久视频在线视频精品| 中国精学生妹品射精久久| 最近中文字幕mv在线资源| 亚洲欧美日韩愉拍自拍美利坚| 午夜伦费影视在线观看| 男女作爱免费网站| 亚洲va在线va天堂xxxx中文| 亚洲伊人久久精品酒店| 欧美又大又硬又粗bbbbb|