在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CHRNB1 Antibody

  • 中文名稱:
    CHRNB1兔多克隆抗體
  • 貨號(hào):
    CSB-PA006822
  • 規(guī)格:
    ¥1090
  • 圖片:
    • Western Blot analysis of Hela cells using AChRβ1 Polyclonal Antibody
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Acetylcholine receptor protein beta chain precursor antibody; Acetylcholine receptor subunit beta antibody; ACHB_HUMAN antibody; AChR antibody; ACHRB antibody; Cholinergic receptor nicotinic beta polypeptide 1 (muscle) antibody; Chrnb 1 antibody; CHRNB antibody; chrnb1 antibody; CMS1D antibody; CMS2A antibody; Nicotinic acetylcholine receptor beta subunit precursor antibody; SCCMS antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the N-terminal region of Human AChRβ1.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:5000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  • 基因功能參考文獻(xiàn):
    1. Study traced the cause of congenital myasthenia syndrome in unrelated patients with dominant missense mutations in the M2 domain of AChR. A valine residue is replaced by a smaller alanine either in the epsilon subunit or an equivalent position in the beta one. Also, each valine in the valine ring was found to contribute to channel kinetics equally, and the valine ring has bee optimized during evolution to govern channe... PMID: 27375219
    2. This study reports on the presence of the CHRNB1 at the cellular level in human skeletal muscle and placenta and that mRNA expression mirrors that of protein within cell types. PMID: 28153524
    3. These findings identify novel Golgi retention signals in the beta and delta subunit loops that regulate surface trafficking of assembled AChR and may help prevent surface expression of unassembled subunits. PMID: 24240098
    4. Single nucleotide polymorphisms , rs55633891 (alpha9, C>T) and rs17856697 (beta1, A>G), did not exhibit a significant trend to be associated with cervical lesions. PMID: 22406075
    5. the beta1 subunit showed significantly increased expression in lung tumors as compared to non-tumor bronchial tissue PMID: 17015027
    6. Extracellular beta1-beta2 and cysteine-loops bridge the pre-M1 transmembrane domain and M2-M3 linker to transduce agonist binding into channel gating. PMID: 19279256

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Myasthenic syndrome, congenital, 2A, slow-channel (CMS2A); Myasthenic syndrome, congenital, 2C, associated with acetylcholine receptor deficiency (CMS2C)
  • 亞細(xì)胞定位:
    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Beta-1/CHRNB1 sub-subfamily
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 1961

    OMIM: 100710

    KEGG: hsa:1140

    STRING: 9606.ENSP00000304290

    UniGene: Hs.330386



主站蜘蛛池模板: 久久久午夜精品福利内容| 国产亚洲曝欧美不卡精品| 性xxxx18免费观看视频| 亚洲妇熟xxxx妇色黄| 亚洲欧洲无码av电影在线观看 | 午夜亚洲国产理论片中文| 无码乱人伦一区二区亚洲| 亚洲欧美日韩综合一区二区| 国产亚洲精品欧洲在线视频| 免费无遮挡在线观看网站| 无码人妻丰满熟妇奶水区码| 日韩中文字幕在线一区二区三区 | 无码中出人妻中文字幕av | 亚洲精品无播放器在线播放| 天天爽天天爽夜夜爽毛片| 无码专区—va亚洲v天堂麻豆| 青楼妓女禁脔道具调教sm| 国产成人av一区二区三区不卡| 玩弄japan白嫩少妇hd| 亚洲色成人网站永久| 欧美va久久久噜噜噜久久| 99国产精品久久久久久久日本竹| 亚洲精品熟女国产| 又大又粗又爽免费视频a片| 国偷自产视频一区二区久| 久久人搡人人玩人妻精品首页| 亚洲mv国产mv在线mv综合试看| 激情国产av做激情国产爱| 18禁止看的免费污网站| 国产女人高潮视频在线观看| 国产午夜免费高清久久影院 | 日日噜噜夜夜狠狠va视频v| 国产精品高清视亚洲中文| 欧美特黄特色三级视频在线观看| 无码一区二区三区视频| 亚洲妇女无套内射精| 大香伊蕉在人线国产最新75 | 欧美国产亚洲日韩在线二区| 欧美内射深喉中文字幕| 乱中年女人伦av一区二区| 18禁无遮挡羞羞污污污污网站|