在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CDON Antibody

  • 中文名稱:
    CDON兔多克隆抗體
  • 貨號:
    CSB-PA005100GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    CDO antibody; Cdon antibody; CDON_HUMAN antibody; Cell adhesion molecule-related/down-regulated by oncogenes antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human CDON
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells.
  • 基因功能參考文獻:
    1. We identified a novel heterozygous nonsense CDON mutation in a case of Pituitary Stalk Interruption Syndrome who presented with neonatal hypoglycemia and cholestasis PMID: 26529631
    2. CDO is required for proliferation and survival of lung cancer cells via Hh signaling. PMID: 25369201
    3. These data support the view that cell-adhesion molecule-related/downregulated by oncogenes (CDON) acts as a tumor suppressor in neuroblastomas, and that CDON is tightly regulated by miRNAs. PMID: 25313246
    4. Single-nucleotide polymorphism in CDON is associated with biochemical recurrence in prostate cancer. PMID: 24740842
    5. Mutations in the CDON cause holoprosencephaly. (Review) PMID: 22326621
    6. We found that CDON is overexpressed in prostate cancer PMID: 21849809
    7. CDON must associate with both ligand and other hedgehog-receptor components, particularly PTCH1, for signaling to occur and disruption of the latter interactions is a mechanism of holoprosencephaly. PMID: 21802063
    8. Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner PMID: 20519495
    9. CDO and BOC play a role in differentiation of cells in the skeletal muscle lineage PMID: 12720294
    10. CDO and BOC forms complexes with specific cadherins that mediate some of the promyogenic effects of cell-cell contact. PMID: 12634428
    11. Targeted inactivation of Cdon in the mouse results in mild holoprosencephaly, suggesting a link to signaling pathways that control midline development such as the Sonic hedgehog pathway. PMID: 12620190

    顯示更多

    收起更多

  • 相關疾病:
    Holoprosencephaly 11 (HPE11)
  • 亞細胞定位:
    Cell membrane; Single-pass membrane protein.
  • 數據庫鏈接:

    HGNC: 17104

    OMIM: 608707

    KEGG: hsa:50937

    STRING: 9606.ENSP00000263577

    UniGene: Hs.38034



主站蜘蛛池模板: 中文乱码字幕高清一区二区| 激情五月综合色婷婷一区二区| 国产色在线 | 亚洲| 青草影院内射中出高潮| 午夜131美女爱做视频| 最新精品国偷自产在线美女足| 肥老熟妇伦子伦456视频| 国产人与禽zoz0性伦| 国产精品jk白丝在线播放| 久青草国产在视频在线观看| 鲁大师在线视频播放免费观看| 国产suv精品一区二区6| 粗大的内捧猛烈进出少妇视频| 免费无码专区在线视频| 久久人妻天天av| 色爱情人网站| 日本黄漫动漫在线观看视频| 真人与拘做受免费视频一| 呦系列视频一区二区三区| 国产丝袜无码一区二区视频| 男生白内裤自慰gv白袜男同| 午夜福利伦伦电影理论片在线观看| 一 级做人爱全视频在线看| 亚洲国产成在人网站天堂| 把腿张开老子臊烂你多p视频| 99精品欧美一区二区三区| 久久综合久久美利坚合众国| 忘忧草日本在线播放www| 久久不见久久见www电影免费| 欧美变态另类刺激| 亚洲国产成人极品综合| 无码人妻天天拍夜夜爽 | 亚洲女人色综合小说| 精品无码成人片一区二区98| 福利姬液液酱喷水| av在线亚洲欧洲日产一区二区| 麻豆果冻传媒2021精品传媒一区下载 | 免费拍拍拍网站| 亚洲一区 日韩精品 中文字幕 | 欧美交换配乱吟粗大25p| 欧美中文亚洲v在线|