在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CDON Antibody

  • 中文名稱:
    CDON兔多克隆抗體
  • 貨號:
    CSB-PA242369
  • 規格:
    ¥2024
  • 圖片:
    • Immunofluorescence analysis of MCF-7 cells, using CDON antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CDON Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from internal of Human CDON.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IF 1:100-1:500
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells.
  • 基因功能參考文獻:
    1. We identified a novel heterozygous nonsense CDON mutation in a case of Pituitary Stalk Interruption Syndrome who presented with neonatal hypoglycemia and cholestasis PMID: 26529631
    2. CDO is required for proliferation and survival of lung cancer cells via Hh signaling. PMID: 25369201
    3. These data support the view that cell-adhesion molecule-related/downregulated by oncogenes (CDON) acts as a tumor suppressor in neuroblastomas, and that CDON is tightly regulated by miRNAs. PMID: 25313246
    4. Single-nucleotide polymorphism in CDON is associated with biochemical recurrence in prostate cancer. PMID: 24740842
    5. Mutations in the CDON cause holoprosencephaly. (Review) PMID: 22326621
    6. We found that CDON is overexpressed in prostate cancer PMID: 21849809
    7. CDON must associate with both ligand and other hedgehog-receptor components, particularly PTCH1, for signaling to occur and disruption of the latter interactions is a mechanism of holoprosencephaly. PMID: 21802063
    8. Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner PMID: 20519495
    9. CDO and BOC play a role in differentiation of cells in the skeletal muscle lineage PMID: 12720294
    10. CDO and BOC forms complexes with specific cadherins that mediate some of the promyogenic effects of cell-cell contact. PMID: 12634428
    11. Targeted inactivation of Cdon in the mouse results in mild holoprosencephaly, suggesting a link to signaling pathways that control midline development such as the Sonic hedgehog pathway. PMID: 12620190

    顯示更多

    收起更多

  • 相關疾病:
    Holoprosencephaly 11 (HPE11)
  • 亞細胞定位:
    Cell membrane; Single-pass membrane protein.
  • 數據庫鏈接:

    HGNC: 17104

    OMIM: 608707

    KEGG: hsa:50937

    STRING: 9606.ENSP00000263577

    UniGene: Hs.38034



主站蜘蛛池模板: 野花社区在线www日本| 国产亚洲精品久久久久久老妇小说| 亚洲人成色77777在线观看大战p| 狠狠色婷婷久久综合频道毛片| 国产免费看插插插视频| 亚洲最大av无码国产| 国产精品国产自线拍免费不卡 | 中文字幕无码免费久久99| 国产真实乱人偷精品人妻| 国产剧情麻豆女教师在线观看| 亚洲aⅴ永久无码一区二区三区| 中文字幕av无码人妻| 天天躁夜夜躁狠狠躁2021a2| 波多野结衣人妻| 98国产精品综合一区二区三区| 久久综合给合久久国产免费| 精品国产一区二区三区av色诱| 精选国产av精选一区二区三区 | 四虎影视88aa久久人妻| 亚洲国产成人精品无码区四虎| 国产成年无码v片在线| 最新亚洲春色av无码专区| 久久精品熟女亚州av麻豆 | 亚洲精品国产福利一区二区 | 欧美成 人版中文字幕| 老男人久久青草av高清| 国产成人无码a区视频在线观看| 亚洲精品久久久蜜桃| 婷婷五月综合丁香在线| 欧美阿v高清资源在线| 裸身美女无遮挡永久免费视频| 精品无码一区二区三区爱欲九九 | 男女性杂交内射女bbwxz| 播五月开心婷婷欧美综合| 日本日本乱码伦专区| 亚洲婷婷综合色高清在线| 日韩精品久久久久久久电影蜜臀 | 亚洲精品无码久久久影院相关影片 | 激情综合婷婷色五月蜜桃| 日本三级成本人网站| 日本久久综合久久综合|