在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CD1E Antibody

CD1E Antibody

  • 中文名稱：
    CD1E兔多克隆抗體
  • 貨號：
    CSB-PA001432
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HuvEc cells using CD1e Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    CD_antigen=CD1e antibody; CD1A antibody; CD1e antibody; CD1e antigen antibody; CD1E antigen; e polypeptide antibody; CD1e molecule antibody; CD1E_HUMAN antibody; Differentiation antigen CD1-alpha-3 antibody; hCD1e antibody; Leukocyte differentiation antigen antibody; R2 antibody; R2G1 antibody; sCD1e antibody; soluble antibody; T-cell surface glycoprotein CD1e antibody; T-cell surface glycoprotein CD1e; membrane-associated antibody; T-cell surface glycoprotein CD1e; soluble antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human CD1e.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    T-cell surface glycoprotein CD1e, soluble binds diacetylated lipids, including phosphatidyl inositides and diacylated sulfoglycolipids, and is required for the presentation of glycolipid antigens on the cell surface. The membrane-associated form is not active.
  • 基因功能參考文獻：
    1. There was no association between polymorphisms of CD1E genes and the susceptibilities to Guillain-Barre syndrome. PMID: 27653862
    2. The interaction of LAPTM5 with CD1e and their colocalization in antigen processing compartments both suggest that LAPTM5 might influence the role of CD1e in the presentation of lipid antigens. PMID: 22880058
    3. in the late endosomes/lysosomes of dendritic cells, the acid pH promotes the binding of lipid antigens to CD1e through increased hydrophobic and ionic interactions PMID: 21481186
    4. allelic variation in CD1E does not play a major role in determining multifocal motor neuropathy susceptibility. PMID: 22003931
    5. CD1e may positively or negatively affect lipid presentation by CD1b, CD1c, and CD1d. PMID: 21844346
    6. These data support that CD1e could have evolved to mediate lipid-exchange/editing processes. PMID: 21788486
    7. substitutions lead to amino acid changes at position 73 and 77 of the alpha1 domain in the former and at position 30 of the alpha2 domain in the latter suggesting that the CD1E gene is much more polymorphic than previously assumed. PMID: 12144626
    8. cellular and biochemical properties of the human and simian CD1e molecules are similar, suggesting that the particular intracellular distribution of CD1e is important for its physiological and/or immunological function PMID: 12671734
    9. required for processing of the mycobcterial antigens hexamannosylated phosphatidyl-myo-inositols(PIM6); propose that, through this form of glycolipid editing, CD1e helps expand the repertoire of glycolipidic T cell antigens to optimize immune response PMID: 16311334
    10. Data show that ubiquitination of CD1e appears to trigger its exit from Golgi compartments and its transport to endosomes. PMID: 18208508
    11. A polymorphism related to the capacity of the CD1E molecule to participate in the immune response to complex glycolipids is discovered in individuals who might display a CD1e-altered immune response to complex glycolipid antigens. PMID: 18325888
    12. CD1e propeptide is conserved during evolution, suggesting that it may also optimize the generation of CD1e molecules in other species. PMID: 19196239

    顯示更多

    收起更多

  • 亞細胞定位：
    [T-cell surface glycoprotein CD1e, membrane-associated]: Golgi apparatus membrane; Single-pass type I membrane protein. Early endosome. Late endosome. Note=Predominantly localized in the trans-Golgi network in immature dendritic cells, and as a cleaved, soluble protein in the lysosome lumen of mature dendritic cells.; [T-cell surface glycoprotein CD1e, soluble]: Lysosome lumen.
  • 組織特異性：
    Expressed on cortical thymocytes, dendritic cells, Langerhans cells, on certain T-cell leukemias, and in various other tissues.
  • 數據庫鏈接：

    HGNC: 1638

    OMIM: 188411

    KEGG: hsa:913

    STRING: 9606.ENSP00000357149

    UniGene: Hs.249217



主站蜘蛛池模板： 久久中文字幕无码a片不卡古代| 污污内射久久一区二区欧美日韩| 成人性能视频在线| 人人妻人人添人人爽欧美一区| 超碰aⅴ人人做人人爽| 精品亚洲成a人在线观看青青| 少妇呻吟白浆高潮啪啪69| 亚洲狠亚洲狠亚洲狠狠狠| 亚洲色欲色欲www在线丝| 蜜桃无码一区二区三区| 欧美 亚洲 国产 日韩 综aⅴ| 国产一区二区三区四区精华| 忘忧草社区在线资源www| 又大又紧又粉嫩18p少妇| 久久午夜无码鲁丝片午夜精品| 欧美人与物videos另类xxxxx| 午夜无码大尺度福利视频| 国产精品久免费的黄牛仔短裤| 亚洲区激情区无码区日韩区| 亚洲精品久久久久中文字幕| 亚洲五月综合缴情在线| 亚洲一卡一卡二新区无人区| 2019久久视频这里有精品15| 黑人与中国少妇xxxx视频| 色综合天天综合网国产成人网| 亚洲国产精品久久一线不卡| 久久精品国产精品| 久久中文字幕无码a片不卡古代| 夜夜夜夜猛噜噜噜噜噜试看| 国产成人精品无码免费看| 国产精品美女被遭强扒开双腿| 亚洲人成网站观看在线播放| 五月综合色婷婷在线观看| www.一区二区三区在线 | 欧洲| 男女无遮挡激情视频| 国产超碰人人爽人人做| 曰韩欧美群交p片内射| 人妻中出无码一区二区三区| 色 综合 欧美 亚洲 国产| 人妻中文无码久热丝袜| 亚洲国产成人精品一区刚刚|