在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CD1E Antibody

  • 中文名稱:
    CD1E兔多克隆抗體
  • 貨號:
    CSB-PA912791
  • 規格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from HuvEc cells and HepG2 cells, using CD1E antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CD1E Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from internal of Human CD1E.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    T-cell surface glycoprotein CD1e, soluble binds diacetylated lipids, including phosphatidyl inositides and diacylated sulfoglycolipids, and is required for the presentation of glycolipid antigens on the cell surface. The membrane-associated form is not active.
  • 基因功能參考文獻:
    1. There was no association between polymorphisms of CD1E genes and the susceptibilities to Guillain-Barre syndrome. PMID: 27653862
    2. The interaction of LAPTM5 with CD1e and their colocalization in antigen processing compartments both suggest that LAPTM5 might influence the role of CD1e in the presentation of lipid antigens. PMID: 22880058
    3. in the late endosomes/lysosomes of dendritic cells, the acid pH promotes the binding of lipid antigens to CD1e through increased hydrophobic and ionic interactions PMID: 21481186
    4. allelic variation in CD1E does not play a major role in determining multifocal motor neuropathy susceptibility. PMID: 22003931
    5. CD1e may positively or negatively affect lipid presentation by CD1b, CD1c, and CD1d. PMID: 21844346
    6. These data support that CD1e could have evolved to mediate lipid-exchange/editing processes. PMID: 21788486
    7. substitutions lead to amino acid changes at position 73 and 77 of the alpha1 domain in the former and at position 30 of the alpha2 domain in the latter suggesting that the CD1E gene is much more polymorphic than previously assumed. PMID: 12144626
    8. cellular and biochemical properties of the human and simian CD1e molecules are similar, suggesting that the particular intracellular distribution of CD1e is important for its physiological and/or immunological function PMID: 12671734
    9. required for processing of the mycobcterial antigens hexamannosylated phosphatidyl-myo-inositols(PIM6); propose that, through this form of glycolipid editing, CD1e helps expand the repertoire of glycolipidic T cell antigens to optimize immune response PMID: 16311334
    10. Data show that ubiquitination of CD1e appears to trigger its exit from Golgi compartments and its transport to endosomes. PMID: 18208508
    11. A polymorphism related to the capacity of the CD1E molecule to participate in the immune response to complex glycolipids is discovered in individuals who might display a CD1e-altered immune response to complex glycolipid antigens. PMID: 18325888
    12. CD1e propeptide is conserved during evolution, suggesting that it may also optimize the generation of CD1e molecules in other species. PMID: 19196239

    顯示更多

    收起更多

  • 亞細胞定位:
    [T-cell surface glycoprotein CD1e, membrane-associated]: Golgi apparatus membrane; Single-pass type I membrane protein. Early endosome. Late endosome. Note=Predominantly localized in the trans-Golgi network in immature dendritic cells, and as a cleaved, soluble protein in the lysosome lumen of mature dendritic cells.; [T-cell surface glycoprotein CD1e, soluble]: Lysosome lumen.
  • 組織特異性:
    Expressed on cortical thymocytes, dendritic cells, Langerhans cells, on certain T-cell leukemias, and in various other tissues.
  • 數據庫鏈接:

    HGNC: 1638

    OMIM: 188411

    KEGG: hsa:913

    STRING: 9606.ENSP00000357149

    UniGene: Hs.249217



主站蜘蛛池模板: 69国产成人精品午夜福中文| 一二三区乱码不卡手机版| 中出あ人妻熟女中文字幕| 国产午夜无码片在线观看网站| 顶级少妇做爰视频在线观看| 99亚洲男女激情在线观看| 国产人妻久久精品二区三区特黄| 99re8精品视频热线观看| 中文字幕制服丝袜人妻动态图| 成人免费区一区二区三区| 国产精品久久久久影院| 中文字幕+乱码+中文乱码www| 国产精品玖玖玖在线| 男女裸体影院高潮| 东京道一本热中文字幕| 强伦姧人妻免费无码电影| 亚洲а∨天堂男人色无码| 亚洲精品一区二区三区四区五区| 亚洲欧美日韩国产综合一区二区| 欧美特级婬片毛多的少妇| 插一插射一射视频| 一卡二卡三卡视频| 亚洲国产成人久久综合人| 九九久久精品国产波多野结衣| 各种少妇正面bbw撒尿| 亚洲精品成人a在线观看| 无码任你躁久久久久久老妇蜜桃| 国产精品亚洲专区无码破解版| 国产乱人伦app精品久久| 超清无码av最大网站| 久久国产精品老女人| 成年女人毛片免费视频| 毛片tv网站无套内射tv网站| 四库影院永久国产精品地址 | 亚洲日本乱码在线观看| 少妇一晚三次一区二区三区| 国产精品久久久久久久久动漫 | 亚洲乱码卡一卡二卡| 成年美女黄网站18禁免费| 国产精品夜间视频香蕉| 亚洲高清国产av拍精品青青草原|