在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CA1 Antibody

  • 中文名稱:
    CA1兔多克隆抗體
  • 貨號:
    CSB-PA348998
  • 規(guī)格:
    ¥1100
  • 圖片:
    • Gel: 10%SDS-PAGE, Lysate: 24 μg, Lane: Human lung cancer tissue, Primary antibody: CSB-PA348998(CA1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    CA 1 antibody; CA I antibody; CA-I antibody; CA1 antibody; CAB antibody; CAH1_HUMAN antibody; CAI antibody; CAN antibody; Car 1 antibody; Car1 antibody; Carbonate dehydratase I antibody; Carbonic anhydrase 1 antibody; Carbonic anhydrase A antibody; Carbonic anhydrase B antibody; Carbonic anhydrase B; formerly antibody; Carbonic anhydrase I antibody; Carbonic dehydratase antibody; ECK0125 antibody; JW0122 antibody; yadF antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Rat
  • 免疫原:
    Fusion protein of Human CA1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    WB 1:200-1:1000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.
  • 基因功能參考文獻:
    1. Anti-CA I and II antibody levels were investigated using ELISA in serum samples from 30 patients with Acute Myeloid Leukemia (AML) and 30 healthy peers. Anti-CA I and II antibody titers in the AML group were significantly higher compared with the control group (p=0.0001 and 0.018, respectively). PMID: 28270370
    2. These six-membered carbocycles showed nice inhibitory action against AChE and human carbonic anhydrase (hCA) II and I isoforms. The hCA I, II, and AChE were efficiently inhibited by these molecules, with Ki values in the range of 6.70-35.85 nM for hCA I, 18.77-60.84 nM for hCA II, and 0.74-4.60 for AChE, respectively PMID: 28613396
    3. These results showed that flavonoids especially malvin and oenin effectively inhibited hCA I and II isoenzymes. PMID: 28445001
    4. Discovery of potent carbonic anhydrase, acetylcholinesterase, and butyrylcholinesterase enzymes inhibitors: The new amides and thiazolidine-4-ones synthesized on an acetophenone base. PMID: 28544359
    5. Here are presented solved the first crystal structures of carbonic anhydrase 1and carbonic anhydrase 2 in complex with polmacoxib, at 2.0 A and 1.8 A, respectively. PMID: 27475498
    6. Neuronal carbonic anhydrase I (CA1) appears to be associated with the endoplasmic reticulum subcellular structure. PMID: 27809276
    7. CA1 is highly expressed in the sera of stage I non-small cell lung cancer patients PMID: 26232327
    8. We demonstrated that resveratrol, caffeic acid, and tannic acid in stored blood could decrease the sensitivity to oxidation of erythrocytes in vitro but did not exhibit such effects on Carbonic Anhydrase activity. PMID: 27413740
    9. CA1 is a potential oncogene and that it contributes to abnormal cell calcification, apoptosis and migration in breast cancer. PMID: 26459317
    10. We report on the competitive zinc metalation of apo-carbonic anhydrase [CA; metal-free CA (apo-CA)] in the presence of apo-metallothionein 1A domain fragments to identify domain specific determinants of zinc binding and zinc donation PMID: 26475450
    11. The gene encoding CA1 is susceptible to ankylosing spondylitis and plays a role in the process of bone formation. PMID: 22838845
    12. Structure-activity relationships study showed that indolylchalcone derivatives have higher inhibitory activities than pyrido[2,3-d]pyrimidine derivatives on hCA I and hCA II. PMID: 25165709
    13. Myocardial carbonic anhydrase 1/2 activation is significantly elevated in diabetic ischemic cardiomyopathy. PMID: 24670789
    14. may be involved in the pathogenesis of Abdominal aortic aneurysm PMID: 23557951
    15. The new prognostic biomarkers GRP78, Fructose-bisphosphate Aldolase A (ALDOA), Carbonic Anhydrase I (CA1) and Peptidyl-prolyl cis-trans isomerase A or Cyclophilin A (PPIA)) provided good survival prediction for TNM stage I-IV patients. PMID: 22996014
    16. A significant correlation was found between positive carbonic anhydrase I staining and oral squamous cell carcinoma for more advanced clinical stage and larger tumor size, but not for positive lymph node metastasis, distal metastasis, and recurrence. PMID: 22416960
    17. carbonic anhydrase I, phosphoglycerate kinase 1 and apolipoprotein A-I appeared to be the most significant variations of proteins in patients with osteopenia and osteoarthritis PMID: 22619369
    18. A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration. PMID: 22360420
    19. Overexpression of CA1 in the synovial tissues of ankylosing spondylitis (AS) patients may promote improper calcification and bone resorption in AS. PMID: 21143847
    20. single mutation of an amino acid not considered essential to catalysis (Phe91Asn) in carbonic anhydrase I, but is near substrate binding pocket, led to increase of catalytic activity; mutant CA I also showed higher affinity for sulfonamide inhibitors PMID: 20624682
    21. The X-ray crystallographic structure of the CA I Michigan 1 variant isozyme is reported, both in the presence and absence of a second bound zinc ion coordinated to His 64, His 200, and Arg 67. PMID: 12009884
    22. concentrations in nondialyzed chronic kidney disease patients, and the relationship with acidosis, zinc, anemia, and iron supplementation PMID: 14675565
    23. cytosolic CA I, II, and XIII are downregulated in neoplastic colorectal mucosa compared to normal colorectal mucosa PMID: 15836783
    24. Isothiocyanato sulfonamide thioureas inhibit this enzyme. PMID: 15837325
    25. X-ray crystallographic structure for the adduct of an activator with hCA I. Binding site interactions of activator L-Histidine with active site amino acids PMID: 16870440
    26. study presents the X-ray structure of the foscarnet adduct with CA1 together with the factors governing recognition of such small molecules by a metalloenzyme active site PMID: 17314045
    27. Decreased levels of carbonic anhydrase 1 isozyme is associated with type II diabetes. PMID: 17464559

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Alpha-carbonic anhydrase family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 1368

    OMIM: 114800

    KEGG: hsa:759

    STRING: 9606.ENSP00000256119

    UniGene: Hs.23118



主站蜘蛛池模板: 国产亚洲精品久久久久久| 国产精品久久久久一区二区三区| 人人妻人人玩人人澡人人爽| 色综合99久久久无码国产精品 | 久久精品女人的天堂av| 国产成在线观看免费视频| 亚洲精品国产高清一线久久| 人妻少妇精品久久久久久| 亚欧成a人无码精品va片| 好男人资源在线www免费| 国产卡一卡二卡三精品| 亚洲最大的成人网| 人妻系列无码专区久久五月天| 久久无码国产专区精品| 蜜乳av久久久久久久久久久| 怡红院成永久免费人视频新的| 久久超乳爆乳中文字幕| 欧美性猛交xxxx乱大交丰满| 亚洲精品一本之道高清乱码| 中国真实偷乱视频| 国产黄a三级三级三级| 欧洲多毛裸体xxxxx| 亚洲无人区午夜福利码高清完整版| 亚洲人成网站18禁止一区| 男女啪啪永久免费观看网站| 精品国产乱码久久久久久夜深人妻| 97超碰中文字幕久久精品| 天堂中文а√在线官网| 天天做天天爱天天爽综合网| 亚洲国产精品一区二区动图| 久久精品娱乐亚洲领先| 欧美老熟妇欲乱高清视频| 97无码免费人妻超级碰碰夜夜| 丁香五月网久久综合| 国产成人av一区二区三区在线观看 | 丁香婷婷激情综合俺也去| h人成在线看免费视频| 国产精品v欧美精品v日韩精品| 欧美一区二区三区视频在线观看| 极品少妇被猛得白浆直喷白浆小说| 202丰满熟女妇大|