在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CA1 Antibody

  • 中文名稱:
    CA1兔多克隆抗體
  • 貨號:
    CSB-PA004364HA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA004364HA01HU at dilution of 1:100
    • Immunofluorescent analysis of A549 cells using CSB-PA004364HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Western Blot
      Positive WB detected in: K562 whole cell lysate, Mouse spleen tissue, Mouse kidney tissue
      All lanes: CA1 antibody at 6.5µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 29 kDa
      Observed band size: 29 kDa
    • Immunoprecipitating CA1 in K562 whole cell lysate
      Lane 1: Rabbit control IgG instead of CSB-PA004364HA01HU in K562 whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
      Lane 2: CSB-PA004364HA01HU (8µg) + K562 whole cell lysate (500µg)
      Lane 3: K562 whole cell lysate (20µg)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CA1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    CA 1 antibody; CA I antibody; CA-I antibody; CA1 antibody; CAB antibody; CAH1_HUMAN antibody; CAI antibody; CAN antibody; Car 1 antibody; Car1 antibody; Carbonate dehydratase I antibody; Carbonic anhydrase 1 antibody; Carbonic anhydrase A antibody; Carbonic anhydrase B antibody; Carbonic anhydrase B; formerly antibody; Carbonic anhydrase I antibody; Carbonic dehydratase antibody; ECK0125 antibody; JW0122 antibody; yadF antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Carbonic anhydrase 1 protein (2-261AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,CA1 Antibody (CSB-PA004364HA01HU),的標記方式是Non-conjugated。對于CA1 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA004364HB01HU CA1 Antibody, HRP conjugated ELISA
    FITC CSB-PA004364HC01HU CA1 Antibody, FITC conjugated
    Biotin CSB-PA004364HD01HU CA1 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC, IF, IP
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
    IP 1:200-1:2000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.
  • 基因功能參考文獻:
    1. Anti-CA I and II antibody levels were investigated using ELISA in serum samples from 30 patients with Acute Myeloid Leukemia (AML) and 30 healthy peers. Anti-CA I and II antibody titers in the AML group were significantly higher compared with the control group (p=0.0001 and 0.018, respectively). PMID: 28270370
    2. These six-membered carbocycles showed nice inhibitory action against AChE and human carbonic anhydrase (hCA) II and I isoforms. The hCA I, II, and AChE were efficiently inhibited by these molecules, with Ki values in the range of 6.70-35.85 nM for hCA I, 18.77-60.84 nM for hCA II, and 0.74-4.60 for AChE, respectively PMID: 28613396
    3. These results showed that flavonoids especially malvin and oenin effectively inhibited hCA I and II isoenzymes. PMID: 28445001
    4. Discovery of potent carbonic anhydrase, acetylcholinesterase, and butyrylcholinesterase enzymes inhibitors: The new amides and thiazolidine-4-ones synthesized on an acetophenone base. PMID: 28544359
    5. Here are presented solved the first crystal structures of carbonic anhydrase 1and carbonic anhydrase 2 in complex with polmacoxib, at 2.0 A and 1.8 A, respectively. PMID: 27475498
    6. Neuronal carbonic anhydrase I (CA1) appears to be associated with the endoplasmic reticulum subcellular structure. PMID: 27809276
    7. CA1 is highly expressed in the sera of stage I non-small cell lung cancer patients PMID: 26232327
    8. We demonstrated that resveratrol, caffeic acid, and tannic acid in stored blood could decrease the sensitivity to oxidation of erythrocytes in vitro but did not exhibit such effects on Carbonic Anhydrase activity. PMID: 27413740
    9. CA1 is a potential oncogene and that it contributes to abnormal cell calcification, apoptosis and migration in breast cancer. PMID: 26459317
    10. We report on the competitive zinc metalation of apo-carbonic anhydrase [CA; metal-free CA (apo-CA)] in the presence of apo-metallothionein 1A domain fragments to identify domain specific determinants of zinc binding and zinc donation PMID: 26475450
    11. The gene encoding CA1 is susceptible to ankylosing spondylitis and plays a role in the process of bone formation. PMID: 22838845
    12. Structure-activity relationships study showed that indolylchalcone derivatives have higher inhibitory activities than pyrido[2,3-d]pyrimidine derivatives on hCA I and hCA II. PMID: 25165709
    13. Myocardial carbonic anhydrase 1/2 activation is significantly elevated in diabetic ischemic cardiomyopathy. PMID: 24670789
    14. may be involved in the pathogenesis of Abdominal aortic aneurysm PMID: 23557951
    15. The new prognostic biomarkers GRP78, Fructose-bisphosphate Aldolase A (ALDOA), Carbonic Anhydrase I (CA1) and Peptidyl-prolyl cis-trans isomerase A or Cyclophilin A (PPIA)) provided good survival prediction for TNM stage I-IV patients. PMID: 22996014
    16. A significant correlation was found between positive carbonic anhydrase I staining and oral squamous cell carcinoma for more advanced clinical stage and larger tumor size, but not for positive lymph node metastasis, distal metastasis, and recurrence. PMID: 22416960
    17. carbonic anhydrase I, phosphoglycerate kinase 1 and apolipoprotein A-I appeared to be the most significant variations of proteins in patients with osteopenia and osteoarthritis PMID: 22619369
    18. A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration. PMID: 22360420
    19. Overexpression of CA1 in the synovial tissues of ankylosing spondylitis (AS) patients may promote improper calcification and bone resorption in AS. PMID: 21143847
    20. single mutation of an amino acid not considered essential to catalysis (Phe91Asn) in carbonic anhydrase I, but is near substrate binding pocket, led to increase of catalytic activity; mutant CA I also showed higher affinity for sulfonamide inhibitors PMID: 20624682
    21. The X-ray crystallographic structure of the CA I Michigan 1 variant isozyme is reported, both in the presence and absence of a second bound zinc ion coordinated to His 64, His 200, and Arg 67. PMID: 12009884
    22. concentrations in nondialyzed chronic kidney disease patients, and the relationship with acidosis, zinc, anemia, and iron supplementation PMID: 14675565
    23. cytosolic CA I, II, and XIII are downregulated in neoplastic colorectal mucosa compared to normal colorectal mucosa PMID: 15836783
    24. Isothiocyanato sulfonamide thioureas inhibit this enzyme. PMID: 15837325
    25. X-ray crystallographic structure for the adduct of an activator with hCA I. Binding site interactions of activator L-Histidine with active site amino acids PMID: 16870440
    26. study presents the X-ray structure of the foscarnet adduct with CA1 together with the factors governing recognition of such small molecules by a metalloenzyme active site PMID: 17314045
    27. Decreased levels of carbonic anhydrase 1 isozyme is associated with type II diabetes. PMID: 17464559

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Alpha-carbonic anhydrase family
  • 數據庫鏈接:

    HGNC: 1368

    OMIM: 114800

    KEGG: hsa:759

    STRING: 9606.ENSP00000256119

    UniGene: Hs.23118



主站蜘蛛池模板: 337p粉嫩日本欧洲亚洲大胆| 人人超人人超碰超国产| 毛片内射久久久一区| 免费纯肉3d动漫无码网站| 亚洲综合小说另类图片五月天| 99久视频只有精品2019| 鲁鲁狠狠狠7777一区二区| 无码福利一区二区三区| 欧美亚洲综合成人a∨在线| 国产欧色美视频综合二区| 动漫无遮挡h纯肉亚洲资源大片| 亚洲色欧美色2019在线| 性xxxx视频播放免费| 久久午夜电影网| 日日天日日夜日日摸| 伊人久久亚洲综合影院首页| 无码人妻av一区二区三区蜜臀| 美女黄18以下禁止观看| 国产精品无码无需播放器| 妺妺窝人体色www在线小说| 欧美丰满肥婆videos| 99久久国产露脸精品竹菊传媒| 蜜桃视频一区二区三区在线观看| 国产精品乱码一区二区三| 日本高清一二三不卡区| 色欲色香天天天综合网站| 午夜一区二区亚洲福利| 亚洲综合色成在线播放| 少妇无码一区二区三区| 少妇高清精品毛片在线视频| 极品少妇扒开粉嫩小泬视频| 久久精品手机观看| 国产精品白丝喷水在线观看 | 国产精品va在线观看无码不卡| 尤物视频在线观看| 特殊重囗味sm在线观看无码| 免费人成视频在线播放视频| 51久久国产露脸精品国产| 中文字幕亚洲无线码一区女同 | 免费无码又爽又刺激激情视频软件 | 久久久精品妇女99|