在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ARL2BP Antibody, Biotin conjugated

ARL2BP Antibody, Biotin conjugated

  • 中文名稱：
    ARL2BP兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA897097HD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ARL2BP Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ARL2BP
  • 別名：
    ADP ribosylation factor like 2 binding protein antibody; ADP-ribosylation factor-like protein 2-binding protein antibody; AR2BP_HUMAN antibody; Arf like 2 binding protein BART1 antibody; ARF-like 2-binding protein antibody; ARL2 binding protein antibody; Arl2bp antibody; ARL2BP protein antibody; BART antibody; BART1 antibody; Binder of ARF2 protein 1 antibody; Binder of Arl Two antibody; Binder of Arl2 antibody; Retinitis pigmentosa 66 (autosomal recessive) antibody; RP66 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human ADP-ribosylation factor-like protein 2-binding protein (1-163AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
  • 基因功能參考文獻：
    1. This study identified two homozygous variants in ARL2BP as a rare cause of autosomal recessive retinitis pigmentosa. Further studies are required to define the underlying disease mechanism causing retinal degeneration as a result of mutations in ARL2BP and any phenotype-genotype correlation associated with residual levels of the wild-type transcript. PMID: 30210231
    2. Subsequent analysis of 844 index cases did not reveal further pathogenic chances in ARL2BP indicating that mutations in ARL2B are a rare cause of arRCD (about 0.1%) in a large cohort of French patients. PMID: 27790702
    3. Alteration of EBV encoded miR-BART1 expression results in an increase in migration and invasion of nasopharyngeal carcinoma in vitro and causes metastasis in vivo. EBV-miR-BART1 directly targets the cellular tumour suppressor PTEN. PMID: 26135619
    4. EBV also downregulates two immediate early genes by miR-BART20-5p. PMID: 24899173
    5. Mutations in ARL2BP cause autosomal-recessive retinitis pigmentosa. PMID: 23849777
    6. EBV-miR-BART1 could influence the expression of metabolism-associated genes and might be involved in cancer metabolism in nasopharyngeal carcinoma PMID: 23685147
    7. Our results imply that BART regulates actin-cytoskeleton rearrangements at membrane ruffles through modulation of the activity of Rac1, which, in turn, inhibits pancreatic cancer cell invasion. PMID: 22745590
    8. These results imply that BART contributes to regulating PKCalpha activity through binding to ANX7, thereby affecting the invasiveness of pancreatic cancer cells. PMID: 22532868
    9. We identify a subset of BART miRNAs that are restricted to Latency III in normal infection but are up regulated in tumors that express Latency I and II. PMID: 21901094
    10. Our results imply that BART increases active RhoA by inhibiting ARL2 function, which in turn inhibits invasiveness of cancer cells. PMID: 21833473
    11. Crystal structure of the ARL2-GTP-BART complex reveals a novel recognition and binding mode of small GTPase with effector. PMID: 19368893

    顯示更多

    收起更多

  • 相關疾病：
    Retinitis pigmentosa with or without situs inversus (RPSI)
  • 亞細胞定位：
    Cytoplasm. Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    ARL2BP family
  • 組織特異性：
    Expressed in retina pigment epithelial cells (at protein level). Widely expressed.
  • 數據庫鏈接：

    HGNC: 17146

    OMIM: 615407

    KEGG: hsa:23568

    STRING: 9606.ENSP00000219204

    UniGene: Hs.632873



主站蜘蛛池模板： 四虎成人精品在永久在线| 中国丰满熟妇xxxx性| 欧美v亚洲v日韩v最新在线| 亚洲成a人片77777国产| 国产v亚洲v天堂a无码99| 一本久久精品一区二区| 精品久久久久久久久久中文字幕| 久久亚洲精品高潮综合色a片| 中文字幕av伊人av无码av狼人| av无码一区二区大桥未久| 最新精品香蕉在线| 久久国产精品无码hdav| 亚洲国产日韩一区三区| 免费无遮挡无码视频在线观看| 无码av波多野结衣久久| 国产成人啪精品视频网站| 高中生粉嫩无套第一次| 乱中年女人伦av三区| 国产精品乱码一区二区三区 | 插插无码视频大全不卡网站| 无码免费毛片手机在线| 最美女人体内射精一区二区| 中文字幕亚洲欧美日韩在线不卡| 亚洲一线二线三线写真| 成人亚洲欧美久久久久| 亚洲国产成人精品无码区在线| 精品人伦一区二区三区蜜桃免费| 久久精品亚洲成在人线av麻豆| 亚洲中文字幕乱码熟女在线| √天堂8资源中文在线| 在线 | 一区二区三区| 日日天日日夜日日摸| 欧美性猛交xxxx乱大交| 一区二区三区视频| 日本丰满熟妇乱子伦| 狠狠色噜噜狠狠狠狠色综合网 | 日韩精品久久久久久免费| 欧美精品久久久久久久自慰| 少妇饥渴偷公乱av在线观看涩爱| 中国少妇xxxx做受| 成人性能视频在线|