在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ARL2BP Antibody

  • 中文名稱:
    ARL2BP兔多克隆抗體
  • 貨號:
    CSB-PA918867
  • 規格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from A549 cells, using ARL2BP antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ARL2BP Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ARL2BP
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from internal of Human ARL2BP.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
  • 基因功能參考文獻:
    1. This study identified two homozygous variants in ARL2BP as a rare cause of autosomal recessive retinitis pigmentosa. Further studies are required to define the underlying disease mechanism causing retinal degeneration as a result of mutations in ARL2BP and any phenotype-genotype correlation associated with residual levels of the wild-type transcript. PMID: 30210231
    2. Subsequent analysis of 844 index cases did not reveal further pathogenic chances in ARL2BP indicating that mutations in ARL2B are a rare cause of arRCD (about 0.1%) in a large cohort of French patients. PMID: 27790702
    3. Alteration of EBV encoded miR-BART1 expression results in an increase in migration and invasion of nasopharyngeal carcinoma in vitro and causes metastasis in vivo. EBV-miR-BART1 directly targets the cellular tumour suppressor PTEN. PMID: 26135619
    4. EBV also downregulates two immediate early genes by miR-BART20-5p. PMID: 24899173
    5. Mutations in ARL2BP cause autosomal-recessive retinitis pigmentosa. PMID: 23849777
    6. EBV-miR-BART1 could influence the expression of metabolism-associated genes and might be involved in cancer metabolism in nasopharyngeal carcinoma PMID: 23685147
    7. Our results imply that BART regulates actin-cytoskeleton rearrangements at membrane ruffles through modulation of the activity of Rac1, which, in turn, inhibits pancreatic cancer cell invasion. PMID: 22745590
    8. These results imply that BART contributes to regulating PKCalpha activity through binding to ANX7, thereby affecting the invasiveness of pancreatic cancer cells. PMID: 22532868
    9. We identify a subset of BART miRNAs that are restricted to Latency III in normal infection but are up regulated in tumors that express Latency I and II. PMID: 21901094
    10. Our results imply that BART increases active RhoA by inhibiting ARL2 function, which in turn inhibits invasiveness of cancer cells. PMID: 21833473
    11. Crystal structure of the ARL2-GTP-BART complex reveals a novel recognition and binding mode of small GTPase with effector. PMID: 19368893

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Retinitis pigmentosa with or without situs inversus (RPSI)
  • 亞細胞定位:
    Cytoplasm. Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族:
    ARL2BP family
  • 組織特異性:
    Expressed in retina pigment epithelial cells (at protein level). Widely expressed.
  • 數據庫鏈接:

    HGNC: 17146

    OMIM: 615407

    KEGG: hsa:23568

    STRING: 9606.ENSP00000219204

    UniGene: Hs.632873



主站蜘蛛池模板: 欧美老熟妇乱子| 熟女熟妇伦av网站| 亚洲精品夜夜夜妓女网| 少妇爱做高清免费视频| av大尺度一区二区三区| 国产午夜福利视频在线观看| 精品一区精品二区制服| 国产高潮流白浆免费观看| 国产片免费福利片永久| 热久久视久久精品18| 少妇私密会所按摩到高潮呻吟| 蜜桃av色偷偷av老熟女| 久久99精品国产自在现线小黄鸭 | 蜜桃传媒av免费观看麻豆| 成人午夜亚洲精品无码区| 情侣黄网站免费看| 久久久久久人妻一区精品| 亚洲 自拍 色综合图区av | 国产白嫩护士被弄高潮| 国产a在亚洲线播放| 国内精品久久久久影院嫩草| 国产系列丝袜熟女精品网站| 久久精品无码一区二区三区免费| 岛国av无码免费无禁网站| 男女免费观看做爰视频在线观看 | 热99re久久精品| 国产乱妇乱子在线播放视频| 大屁股熟女白浆一区二区| 亚洲日本一区二区三区在线| 色婷婷久久综合中文久久蜜桃av| 美女mm131爽爽爽作爱| 免费观看又色又爽又湿的视频| 三上悠亚ssⅰn939无码播放| 成在人线av无码免观看午夜网| 成人精品动漫一区二区| 久久久肥妇熟女ⅹxxx毛片 | 香港三日本8a三级少妇三级99| 亚洲人成精品久久久久桥| 人人爽久久久噜人人看| 大屁股熟女一区二区三区| 日韩一区二区三区无码影院|