在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ARL2BP Antibody

ARL2BP Antibody

  • 中文名稱：
    ARL2BP兔多克隆抗體
  • 貨號：
    CSB-PA000975
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of A549 cells using BART1 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    ARL2BP
  • 別名：
    ADP ribosylation factor like 2 binding protein antibody; ADP-ribosylation factor-like protein 2-binding protein antibody; AR2BP_HUMAN antibody; Arf like 2 binding protein BART1 antibody; ARF-like 2-binding protein antibody; ARL2 binding protein antibody; Arl2bp antibody; ARL2BP protein antibody; BART antibody; BART1 antibody; Binder of ARF2 protein 1 antibody; Binder of Arl Two antibody; Binder of Arl2 antibody; Retinitis pigmentosa 66 (autosomal recessive) antibody; RP66 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human BART1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
  • 基因功能參考文獻(xiàn)：
    1. This study identified two homozygous variants in ARL2BP as a rare cause of autosomal recessive retinitis pigmentosa. Further studies are required to define the underlying disease mechanism causing retinal degeneration as a result of mutations in ARL2BP and any phenotype-genotype correlation associated with residual levels of the wild-type transcript. PMID: 30210231
    2. Subsequent analysis of 844 index cases did not reveal further pathogenic chances in ARL2BP indicating that mutations in ARL2B are a rare cause of arRCD (about 0.1%) in a large cohort of French patients. PMID: 27790702
    3. Alteration of EBV encoded miR-BART1 expression results in an increase in migration and invasion of nasopharyngeal carcinoma in vitro and causes metastasis in vivo. EBV-miR-BART1 directly targets the cellular tumour suppressor PTEN. PMID: 26135619
    4. EBV also downregulates two immediate early genes by miR-BART20-5p. PMID: 24899173
    5. Mutations in ARL2BP cause autosomal-recessive retinitis pigmentosa. PMID: 23849777
    6. EBV-miR-BART1 could influence the expression of metabolism-associated genes and might be involved in cancer metabolism in nasopharyngeal carcinoma PMID: 23685147
    7. Our results imply that BART regulates actin-cytoskeleton rearrangements at membrane ruffles through modulation of the activity of Rac1, which, in turn, inhibits pancreatic cancer cell invasion. PMID: 22745590
    8. These results imply that BART contributes to regulating PKCalpha activity through binding to ANX7, thereby affecting the invasiveness of pancreatic cancer cells. PMID: 22532868
    9. We identify a subset of BART miRNAs that are restricted to Latency III in normal infection but are up regulated in tumors that express Latency I and II. PMID: 21901094
    10. Our results imply that BART increases active RhoA by inhibiting ARL2 function, which in turn inhibits invasiveness of cancer cells. PMID: 21833473
    11. Crystal structure of the ARL2-GTP-BART complex reveals a novel recognition and binding mode of small GTPase with effector. PMID: 19368893

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Retinitis pigmentosa with or without situs inversus (RPSI)
  • 亞細(xì)胞定位：
    Cytoplasm. Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    ARL2BP family
  • 組織特異性：
    Expressed in retina pigment epithelial cells (at protein level). Widely expressed.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17146

    OMIM: 615407

    KEGG: hsa:23568

    STRING: 9606.ENSP00000219204

    UniGene: Hs.632873



主站蜘蛛池模板： 在线视频免费观看爽爽爽| 强行从后面挺进人妻| 真人床震高潮全部视频免费| 潮喷失禁大喷水aⅴ无码| 99久久精品无码一区二区三区| 亚洲人成人网站色www| 亚洲欧美日韩国产综合v| 无码精品国产一区二区免费| 国产片av片永久免费观看| 国产无遮挡又黄又爽高潮| 色老板精品视频在线观看| 美女啪啪网站又黄又免费| 国产做爰xxxⅹ高潮视频12p| 极品粉嫩福利午夜在线播放| 99热成人精品热久久| 中国女人高潮hd| 又黄又爽又无遮挡免费的网站| 无码av片av片av无码| 国产午夜福利不卡在线观看| 人妻av无码一区二区三区| 国内露脸中年夫妇交换| 亚洲第一成年免费网站| 午夜肉伦伦影院| 亚洲精品亚洲人成在线下载| 波多野结衣中文字幕一区二区三区| 日韩国产丝袜人妻一二区| 久久无码中文字幕无码| 久久久婷婷五月亚洲97色| 无码视频在线观看| 亚洲熟妇av乱码在线观看| 亚洲日韩av片在线观看| 亚洲国产品综合人成综合网站| 99久久亚洲精品无码毛片| 人人妻人人澡人人爽欧美一区九九 | 国产少妇高潮在线观看| 正在播放国产乱子伦最新视频| 正在播放老肥熟妇露脸| 亚洲欧洲日产国码久在线| 人妻出轨av中文字幕| 亚洲精品国产av成拍色拍婷婷 | 色一情一乱一乱一区99av|