在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. AIFM2 Antibody
  • 中文名稱(chēng)：
    AIFM2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA874794LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA874794LA01HU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Western Blot
      Positive WB detected in: A549 whole cell lysate
      All lanes: AIFM2 antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 41, 37 kDa
      Observed band size: 41 kDa
    • Immunofluorescence staining of HepG2 cells with CSB-PA874794LA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) AIFM2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    AIFM2
  • 別名：
    5430437E11Rik antibody; aifm2 antibody; AIFM2_HUMAN antibody; AMID antibody; Apoptosis inducing factor (AIF) homologous mitochondrion associated inducer of death antibody; Apoptosis inducing factor (AIF) like mitochondrion associated inducer of death antibody; Apoptosis inducing factor mitochondrion associated 2 antibody; Apoptosis-inducing factor 2 antibody; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death antibody; Apoptosis-inducing factor-like mitochondrion-associated inducer of death antibody; Cys51Stop antibody; HGNC11998 antibody; p53 responsive gene 3 antibody; p53 tumor suppressor antibody; p53-responsive gene 3 protein antibody; PRG3 antibody; TRP53 antibody; Tumor protein p53 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Apoptosis-inducing factor 2 protein (110-373AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，AIFM2 Antibody (CSB-PA874794LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于AIFM2 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱(chēng) 應(yīng)用
    HRP CSB-PA874794LB01HU AIFM2 Antibody, HRP conjugated ELISA
    FITC CSB-PA874794LC01HU AIFM2 Antibody, FITC conjugated
    Biotin CSB-PA874794LD01HU AIFM2 Antibody, Biotin conjugated ELISA
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    A NAD(P)H-dependent oxidoreductase involved in cellular oxidative stress response. At the plasma membrane, catalyzes reduction of coenzyme Q/ubiquinone-10 to ubiquinol-10, a lipophilic radical-trapping antioxidant that prevents lipid oxidative damage and consequently ferroptosis. Cooperates with GPX4 to suppress phospholipid peroxidation and ferroptosis. This anti-ferroptotic function is independent of cellular glutathione levels. May play a role in mitochondrial stress signaling. Upon oxidative stress, associates with the lipid peroxidation end product 4-hydroxy-2-nonenal (HNE) forming a lipid adduct devoid of oxidoreductase activity, which then translocates from mitochondria into the nucleus triggering DNA damage and cell death. Capable of DNA binding in a non-sequence specific way.
  • 基因功能參考文獻(xiàn)：
    1. Low AIFM2 expression is associated with T-cell lymphoblastic lymphoma. PMID: 28534937
    2. AIF and its family member protein, AMID, are rotenone-sensitive NADH:ubiquinone oxidoreductases (of the NDH-2 type). PMID: 26063804
    3. HUHS1015 increased nuclear localization of apoptosis-inducing factor-homologous mitochondrion-associated inducer of death (AMID). PMID: 25244912
    4. induces caspase-independent apoptosis PMID: 11980907
    5. encodes a homologue of the apoptosis-inducing factor PMID: 12135761
    6. AMID is a p53-downstream gene involved in tumorigenesis. PMID: 15273740
    7. Reasults establish a link between coenzyme and DNA binding that likely impacts on the physiological role of AMID in cellular apoptosis. PMID: 15958387
    8. study of cellular localization of the endonuclease G, AIF & AMID during apoptosis using bioinformatics and image analysis PMID: 17347867
    9. AIF-M2 lessens survival cell signaling in the presence of foreign (e.g. bacterial and (retro)viral) cytosolic DNA, thus contributing to the onset of apoptosis PMID: 17711848

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Lipid droplet. Cell membrane; Lipid-anchor. Cytoplasm. Mitochondrion membrane. Nucleus.
  • 蛋白家族：
    FAD-dependent oxidoreductase family
  • 組織特異性：
    Detected in most normal tissues as two transcripts of 1.8 and 4.0 kb in length, respectively. Highly expressed in heart, moderately in liver and skeletal muscles, and expressed at low levels in placenta, lung, kidney, and pancreas. Both transcripts expres
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 21411

    OMIM: 605159

    KEGG: hsa:84883

    STRING: 9606.ENSP00000312370

    UniGene: Hs.650680



主站蜘蛛池模板： 正在播放国产乱子伦最新视频| 欧美肥婆性猛交xxxx| 久久99亚洲精品久久久久| 久久伊人av综合影院| 人妻无码久久精品人妻| 无码专区 人妻系列 在线| 免费国产在线精品一区不卡| 婷婷丁香五月缴情视频| 情侣黄网站免费看| 中文字幕亚洲无线码一区女同| 国产在线无码视频一区二区三区| 日韩人妻无码免费视频一区二区 | 99久热在线精品996热是什么| 欧美性生交xxxxx久久久| 国产美女被遭强高潮网站下载| 2022国产日产欧产精品| 欧美综合自拍亚洲综合图| 国产精品igao视频网网址| 亚洲精品一本之道高清乱码| 人妻少妇熟女javhd| 国产精品久久久久久妇女6080| 伊人久久大香线蕉综合直播| 国产成+人+综合+亚洲欧美| 性色av无码不卡中文字幕| 久久久亚洲欧洲日产国码农村| 国产精品sm捆绑调教视频| 日韩久久久久久中文人妻| 真人性囗交69视频| 国产97超碰人人做人人爱| 欧美人与禽z0zo牲伦交| 成人久久久久久久久久久| 黑人糟蹋人妻hd中文字幕| 亚洲欧美日本中文字不卡| 五十路熟妇高熟无码视频| 国产麻豆精品一区| 国产情侣草莓视频在线| 动漫精品中文无码卡通动漫 | 乱子伦一区二区三区| 成年午夜精品久久久精品| 97久久超碰中文字幕| 强行糟蹋人妻hd中文字幕|