在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. AGA Antibody

AGA Antibody

  • 中文名稱：
    AGA兔多克隆抗體
  • 貨號：
    CSB-PA443866
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA443866(AGA Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA443866(AGA Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Mouse kidney tissue, human testis tissue, Human thyroid cancer tissue, Primary antibody: CSB-PA443866(AGA Antibody) at dilution 1/100, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    AGA
  • 別名：
    Aga antibody; AGU antibody; Aspartylglucosaminidase antibody; Aspartylglucosylamine deaspartylase antibody; Aspartylglycosaminuria antibody; ASPG_HUMAN antibody; ASRG antibody; GA antibody; Glycosylasparaginase antibody; Glycosylasparaginase beta chain antibody; N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase antibody; N4 (N acetyl beta glucosaminyl) L asparagine amidase antibody; N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human AGA
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:15-1:50
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins.
  • 基因功能參考文獻：
    1. 1.8A resolution crystal structure of mature G172D mutant of a model missense GA corresponding to a Canadian aspartylglucosaminuria allele; studied the effect of its single amino acid change on substrate processing PMID: 28457719
    2. We show that gene-silenced cells show specifically reduced AGA activity and store globotriaosylceramide. In gene-silenced cells, release of the neurotransmitter acetylcholine is significantly reduced, demonstrating that this model may be used to study specific neuronal functions such as neurotransmitter release in Fabry disease PMID: 27471012
    3. study reports 2 novel aspartylglucosaminidase gene mutations, one in Qatari twins with an early, perinatal presentation not previously described for aspartylglucosaminuria and the other in 3 Turkish children with newly diagnosed aspartylglucosaminuria and a more classical disease course PMID: 23271757
    4. [review] Natural killer (NK) cell tumors, subtypes of myeloid leukemias and T-cell lymphomas respond to ASNase; ovarian carcinomas and other solid tumors have been proposed as additional targets for ASNase, with a potential role for glutaminase. activity. PMID: 21854356
    5. Molecular mechanism for the autoproteolytic activation of aspartylglucosaminidase. PMID: 14616088
    6. A new point mutation, c.44T>G, found in a Finnish compound heterozygote causes a L15R AA substitution in the signal sequence of the AGA enzyme, affecting AGA translocation by altering a critical hydrophobic core structure in the signal sequence. PMID: 15365992
    7. aspartylglucosaminidase may have a role in development of congenital disorders of glycosylation type I PMID: 16435229
    8. The amino acid substitutions in aspartylglucosaminidase responsible for aspartylglucosaminuria were classified and divided in three groups. PMID: 18992224
    9. Increased AGA plasma activity, although a consistent finding in congenital disorders of glycosylation patients, is not specific to this group of disorders. PMID: 19100247

    顯示更多

    收起更多

  • 相關疾病：
    Aspartylglucosaminuria (AGU)
  • 亞細胞定位：
    Lysosome.
  • 蛋白家族：
    Ntn-hydrolase family
  • 數據庫鏈接：

    HGNC: 318

    OMIM: 208400

    KEGG: hsa:175

    STRING: 9606.ENSP00000264595

    UniGene: Hs.207776



主站蜘蛛池模板： 男男车车的车车网站w98免费| 国产麻豆精品精东影业av网站| 亚洲国产成人综合在线不卡| 国产精品久久久久一区二区三区 | 四虎永久在线精品视频免费观看| 综合色区国产亚洲另类| 久久99国产精品久久99| 日韩精品成人无码专区免费| 少妇挑战黑人高潮惨叫| 亚洲熟妇丰满大屁股熟妇图片| 免费观看一区二区三区| 99久久久国产精品免费蜜臀| 超碰国产精品人人做人人爱| 亚洲va中文字幕无码久久不卡| 中文字幕av一区二区三区| 国产精品一区二区久久| 免费人成视频网站在线下载| 玩弄放荡人妻少妇系列| 搡女人真爽免费视频大全| 人妻被按摩师玩弄到潮喷| 亚洲美女视频高清在线看| 少妇私密推油呻吟在线播放| 无码日韩精品一区二区免费| 国产精品白浆在线观看免费| 亚洲精品无码av人在线观看国产| 欧美超级乱婬视频播放| 麻花豆传媒剧国产免费mv入口| 蜜桃网站入口可看18禁| 国产精品专区免费观看软件 | 国产在线视频www色| 女的被弄到高潮娇喘喷水视频| 国产毛片不卡野外视频| 亚洲国产香蕉碰碰人人| 中文字幕日韩欧美一区二区三区| 亚洲红杏成在人线免费视频| 午夜精品久久久久久久四虎| 日韩精品无码不卡无码| 日韩国产成人无码av毛片| 亚洲337少妇裸体艺术| 少妇大胆瓣开下部自慰| 日韩乱码人妻无码超清蜜桃|