在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. AFAP1 Antibody

AFAP1 Antibody

  • 中文名稱：
    AFAP1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA098902
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA098902(AFAP1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human brain malignant glioma tissue, Primary antibody: CSB-PA098902(AFAP1 Antibody) at dilution 1/116, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    AFAP1
  • 別名：
    110 kDa actin filament associated protein antibody; 110 kDa actin filament-associated protein antibody; Actin filament associated protein 1 antibody; Actin filament associated protein 110 kDa antibody; Actin filament-associated protein 1 antibody; AFAP 1 antibody; AFAP 110 antibody; AFAP antibody; AFAP-110 antibody; Afap1 antibody; AFAP1_HUMAN antibody; AFAP110 antibody; FLJ56849 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human AFAP1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:15-1:50
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Can cross-link actin filaments into both network and bundle structures. May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.
  • 基因功能參考文獻(xiàn)：
    1. The observed up-regulation of AFAP1-AS1 in tumor samples compared with ANCTs implies its involvement in breast cancer pathogenesis and potentiates it as a biomarker or therapeutic target. PMID: 29439313
    2. The high LncRNA AFAP1-AS1 expression was significantly related to advanced clinical stage, larger tumor size, earlier tumor metastasis, earlier lymph nodal involvement and vascular invasion. High LncRNA AFAP1-AS1 expression was an unfavorable prognostic factor in various cancers. PMID: 29544748
    3. AFAP-1 is a key mediator in the inflammatory signaling-induced, translocation-independent attenuation of P-glycoprotein efflux in brain capillary endothelial cells. PMID: 28112407
    4. The genotype frequencies of six SNPs in AFAP1, GMDS and PTGFR genes were conformed to Hardy-Weinberg equilibrium (HWE). PMID: 27862086
    5. Data indicate three loci associated with primary open-angle glaucoma (POAG) were located upstream of ATP binding cassette transporter 1 (ABCA1), within actin filament associated protein 1 (AFAP1) and within GDP-mannose 46-dehydratase (GMDS). PMID: 25173105
    6. Methylation of the long noncoding RNA AFAP1-AS1 is reduced in BE and EAC, and its expression inhibits cancer-related biologic functions of EAC cells. PMID: 23333711
    7. AFAP-110 is required for actin stress fiber formation and cell adhesion in MDA-MB 231 breast cancer cells. PMID: 17520695

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton, stress fiber.
  • 組織特異性：
    Low expression in normal breast epithelial cell line MCF-10A and in tumorigenic breast cancer cell lines MCF-7, T-47D and ZR-75-1. Highly expressed in the invasive breast cancer cell lines MDA-MB-231 and MDA-MB-435. Overexpressed in prostate carcinoma.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 24017

    OMIM: 608252

    KEGG: hsa:60312

    STRING: 9606.ENSP00000371983

    UniGene: Hs.529369



主站蜘蛛池模板： 亚洲精品无码精品mv在线观看| 亚洲级αv无码毛片久久精品| 色狠狠av一区二区三区| 免费国产成人高清在线观看网站 | 精品麻豆丝袜高跟鞋av| 亚洲欧美不卡高清在线观看| 无码人妻精品一二三区免费 | 法国白嫩大屁股xxxx| 人妻天天爽夜夜爽精品视频| 少妇激情作爱视频| 蜜桃视频在线观看免费视频网站www| 欧美多人片高潮野外做片黑人| 青青青草国产线观| 亚洲欧美国产制服图片区| 久久综合狠狠综合久久综合88 | 亚洲香蕉aⅴ视频在线播放| 思思久久精品一本到99热| 激情内射亚州一区二区三区爱妻| 亚洲精品成人片在线观看精品字幕 | 国产农村乱辈无码| 免费精品99久久国产综合精品| 天天躁日日躁狠狠躁超碰97| 辽宁熟女高潮狂叫视频| 亚洲精品久久久久一区二区| 爆乳熟妇一区二区三区霸乳 | 中文字幕无码专区人妻系列| 射精区-区区三区| 90后极品粉嫩小泬20p| 亚洲欧美日韩国产综合在线一区| 蜜臀少妇人妻在线| 国产精品偷窥熟女精品视频| 熟女俱乐部五十路六十路av| 无码少妇高潮浪潮av久久| 巨大巨粗巨长 黑人长吊| 色偷偷88888欧美精品久久久| 色v99在线影院| 性亚洲videofree高清| 久久久精品午夜免费不卡| 仙踪林果冻传媒一区二区| 色综合亚洲一区二区小说性色aⅴ| 国产精品亚洲综合色区韩国|