在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. AFAP1 Antibody

AFAP1 Antibody

  • 中文名稱：
    AFAP1兔多克隆抗體
  • 貨號：
    CSB-PA839800ESR2HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA839800ESR2HU at dilution of 1: 100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) AFAP1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    AFAP1
  • 別名：
    110 kDa actin filament associated protein antibody; 110 kDa actin filament-associated protein antibody; Actin filament associated protein 1 antibody; Actin filament associated protein 110 kDa antibody; Actin filament-associated protein 1 antibody; AFAP 1 antibody; AFAP 110 antibody; AFAP antibody; AFAP-110 antibody; Afap1 antibody; AFAP1_HUMAN antibody; AFAP110 antibody; FLJ56849 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Actin filament-associated protein 1 protein (461-730AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Can cross-link actin filaments into both network and bundle structures. May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.
  • 基因功能參考文獻(xiàn)：
    1. The observed up-regulation of AFAP1-AS1 in tumor samples compared with ANCTs implies its involvement in breast cancer pathogenesis and potentiates it as a biomarker or therapeutic target. PMID: 29439313
    2. The high LncRNA AFAP1-AS1 expression was significantly related to advanced clinical stage, larger tumor size, earlier tumor metastasis, earlier lymph nodal involvement and vascular invasion. High LncRNA AFAP1-AS1 expression was an unfavorable prognostic factor in various cancers. PMID: 29544748
    3. AFAP-1 is a key mediator in the inflammatory signaling-induced, translocation-independent attenuation of P-glycoprotein efflux in brain capillary endothelial cells. PMID: 28112407
    4. The genotype frequencies of six SNPs in AFAP1, GMDS and PTGFR genes were conformed to Hardy-Weinberg equilibrium (HWE). PMID: 27862086
    5. Data indicate three loci associated with primary open-angle glaucoma (POAG) were located upstream of ATP binding cassette transporter 1 (ABCA1), within actin filament associated protein 1 (AFAP1) and within GDP-mannose 46-dehydratase (GMDS). PMID: 25173105
    6. Methylation of the long noncoding RNA AFAP1-AS1 is reduced in BE and EAC, and its expression inhibits cancer-related biologic functions of EAC cells. PMID: 23333711
    7. AFAP-110 is required for actin stress fiber formation and cell adhesion in MDA-MB 231 breast cancer cells. PMID: 17520695

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton, stress fiber.
  • 組織特異性：
    Low expression in normal breast epithelial cell line MCF-10A and in tumorigenic breast cancer cell lines MCF-7, T-47D and ZR-75-1. Highly expressed in the invasive breast cancer cell lines MDA-MB-231 and MDA-MB-435. Overexpressed in prostate carcinoma.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24017

    OMIM: 608252

    KEGG: hsa:60312

    STRING: 9606.ENSP00000371983

    UniGene: Hs.529369



主站蜘蛛池模板： 亚洲aⅴ天堂av天堂无码麻豆| 国产精品亚洲欧美中字| 亚洲自偷精品视频自拍| 精品人妻少妇一区二区三区在线| 国产福利在线视频蜜芽tv| 丝袜熟女国偷自产中文字幕亚洲| 茄子视频国产在线观看| 丰满人妻熟妇乱又伦精品软件| 国产亚洲综合区成人国产| 让少妇高潮无乱码高清在线观看| 久久久久99精品成人片| 国产激情精品一区二区三区| 亚洲人成无码区在线观看| 亚洲精品第一国产综合国服瑶 | 丰满熟女人妻一区二区三| 亚洲欧美日韩中文久久| 国产精品人妻久久毛片高清无卡| 成人乱码一区二区三区四区| 中文人妻熟女乱又乱精品| 久久婷婷五月综合色精品| 日本毛茸茸的丰满熟妇| 国产播放隔着超薄丝袜进入| 久久国语露脸国产精品电影| 性欧美牲交在线视频| 国语自产拍在线观看对白| 51国产偷自视频区视频| 日本高清www午色夜com| 无码国产精品高清免费| 国产裸体xxxx视频| 老熟女重囗味hdxx69| 久久视频这里只精品| 亚洲va中文字幕无码一二三区| 一本大道伊人av久久乱码| 色翁荡熄又大又硬又粗又视频| 真人做受试看120分钟小视频| 国产av无码专区亚洲精品| 亚洲综合精品成人| 狠狠躁天天躁中文字幕无码| 国产情侣一区二区三区| 亚洲综合无码无在线观看| 中文字幕一区二区三区乱码|