在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. AFAP1 Antibody

AFAP1 Antibody

  • 中文名稱：
    AFAP1兔多克隆抗體
  • 貨號：
    CSB-PA154373
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA154373(AFAP1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA154373(AFAP1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: A172 cells, Primary antibody: CSB-PA154373(AFAP1 Antibody) at dilution 1/134, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    AFAP1
  • 別名：
    110 kDa actin filament associated protein antibody; 110 kDa actin filament-associated protein antibody; Actin filament associated protein 1 antibody; Actin filament associated protein 110 kDa antibody; Actin filament-associated protein 1 antibody; AFAP 1 antibody; AFAP 110 antibody; AFAP antibody; AFAP-110 antibody; Afap1 antibody; AFAP1_HUMAN antibody; AFAP110 antibody; FLJ56849 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human AFAP1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Can cross-link actin filaments into both network and bundle structures. May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.
  • 基因功能參考文獻(xiàn)：
    1. The observed up-regulation of AFAP1-AS1 in tumor samples compared with ANCTs implies its involvement in breast cancer pathogenesis and potentiates it as a biomarker or therapeutic target. PMID: 29439313
    2. The high LncRNA AFAP1-AS1 expression was significantly related to advanced clinical stage, larger tumor size, earlier tumor metastasis, earlier lymph nodal involvement and vascular invasion. High LncRNA AFAP1-AS1 expression was an unfavorable prognostic factor in various cancers. PMID: 29544748
    3. AFAP-1 is a key mediator in the inflammatory signaling-induced, translocation-independent attenuation of P-glycoprotein efflux in brain capillary endothelial cells. PMID: 28112407
    4. The genotype frequencies of six SNPs in AFAP1, GMDS and PTGFR genes were conformed to Hardy-Weinberg equilibrium (HWE). PMID: 27862086
    5. Data indicate three loci associated with primary open-angle glaucoma (POAG) were located upstream of ATP binding cassette transporter 1 (ABCA1), within actin filament associated protein 1 (AFAP1) and within GDP-mannose 46-dehydratase (GMDS). PMID: 25173105
    6. Methylation of the long noncoding RNA AFAP1-AS1 is reduced in BE and EAC, and its expression inhibits cancer-related biologic functions of EAC cells. PMID: 23333711
    7. AFAP-110 is required for actin stress fiber formation and cell adhesion in MDA-MB 231 breast cancer cells. PMID: 17520695

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton, stress fiber.
  • 組織特異性：
    Low expression in normal breast epithelial cell line MCF-10A and in tumorigenic breast cancer cell lines MCF-7, T-47D and ZR-75-1. Highly expressed in the invasive breast cancer cell lines MDA-MB-231 and MDA-MB-435. Overexpressed in prostate carcinoma.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24017

    OMIM: 608252

    KEGG: hsa:60312

    STRING: 9606.ENSP00000371983

    UniGene: Hs.529369



主站蜘蛛池模板： 97影院在线午夜| 久久久久无码国产精品一区| 8天堂资源在线| 任你干视频精品播放| 国产精品三级av三级av三级| 超薄丝袜足j好爽在线| 国产精品99久久免费黑人人妻| 色多多www视频在线观看免费| 亚洲精品一区二区国产精华液| 午夜dv内射一区二区| 亚洲精品无码久久久久久| 影音先锋在线亚洲网站| 无码人妻在线一区二区三区免费 | 亚洲一区二区| 躁躁躁日日躁| 大学生被内谢粉嫩无套| 成熟老妇女毛茸茸的做性 | 亚洲乱码日产精品bd在观看| 国产亚洲精品自在久久| 亚洲精品第一国产综合境外资源| 精品无码久久久久国产电影| 在线视频观看免费视频18| 久久久久久欧美精品se一二三四| 久久综合九色综合欧美就去吻| 97久久超碰中文字幕| 亚洲色大成网站www永久男同| 24小时日本在线www免费的 | 国产亚洲精品a久久777777| 无套内谢孕妇毛片免费看| 人妻精品国产一区二区| 337p日本大胆欧美裸体艺术| 亚洲日韩一区精品射精| 蜜臀aⅴ国产精品久久久国产老师| 日韩av无码精品一二三区| 成人精品免费视频在线观看| 国产专区一线二线三线码| 亚洲美女被黑人巨大在线播放| 扒开双腿吃奶呻吟做受视频| 2020国产精品永久在线| 天天狠天天添日日拍| 蜜桃av抽搐高潮一区二区|