在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ACTR2 Antibody

ACTR2 Antibody

  • 中文名稱：
    ACTR2兔多克隆抗體
  • 貨號：
    CSB-PA786075
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA786075(ACTR2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA786075(ACTR2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    ACTR2
  • 別名：
    Actin like protein 2 antibody; Actin related protein 2 antibody; Actin-like protein 2 antibody; Actin-related protein 2 antibody; ACTR2 antibody; ARP2 actin related protein 2 homolog (yeast) antibody; ARP2 antibody; ARP2/3 COMPLEX antibody; ARP2_HUMAN antibody; OTTHUMP00000159937 antibody; OTTHUMP00000202270 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human ACTR2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. In podocytes, required for the formation of lamellipodia downstream of AVIL and PLCE1 regulation. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
  • 基因功能參考文獻：
    1. We speculate that ACTR2 and MEIS1 might respectively play a role in the pathogenesis of the observed deafness and cardiomyopathy...the patient carrying a 2p14p15 deletion including OTX1 had normal kidneys and genitalia, thus confirming that OTX1 haploinsufficiency is not invariably associated with genitourinary defects. PMID: 28599093
    2. this study identified roles for ARP2 and filopodia in human respiratory syncytial virus -induced cell motility, virus production, and cell-to-cell spread. PMID: 27926942
    3. Coronin3 can regulate gastric cancer (GC) invasion and metastasis through Arp2, and the combination of Coronin3 and Arp2 provides a potential marker for predicting GC prognosis. PMID: 24918434
    4. Neural Wiskott-Aldrich syndrome protein (N-WASP)-mediated p120-catenin interaction with Arp2-Actin complex stabilizes endothelial adherens junctions. PMID: 23212915
    5. Using molecular dynamics simulations and biochemical assays with recombinant Arp2/3 complex, we now show how phosphorylation of Arp2 induces conformational changes permitting activation. PMID: 22125478
    6. ARP2-mediated actin polymerization is regulated by phosphorylation of WASP protein. PMID: 12791263
    7. Coexpression of Arp2 and WAVE2 is correlated with poorer patient outcome. PMID: 16638851
    8. High mRNA levels of Arp2 were significantly associated with liver metastasis of colorectal cancer. PMID: 17459058
    9. Arp2-depleted Jurkat T lymphocytes exhibit defects in spreading on anti-CD3; Arp2-depleted Jurkats exhibit defects in ruffle assembly but not in assembly of mitotic linear protrusions. PMID: 18720401

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton. Cell projection. Nucleus.
  • 蛋白家族：
    Actin family, ARP2 subfamily
  • 數據庫鏈接：

    HGNC: 169

    OMIM: 604221

    KEGG: hsa:10097

    STRING: 9606.ENSP00000367220

    UniGene: Hs.643727



主站蜘蛛池模板： 影音先锋女人aa鲁色资源| 国产精品毛片更新无码| 人妻少妇乱子伦精品无码专区电影 | 欧美老妇与禽交| 黑人大群体交免费视频| 超碰香蕉人人网99精品| 人人澡人人曰人人摸看| 国产免费午夜a无码v视频| av在线播放日韩亚洲欧| 男女性杂交内射妇女bbwxz| 亚洲欧美成人a∨观看| 精品国产乱码久久久软件下载| 亚洲人成人网站在线观看| 国产女人被狂躁到高潮小说| 欧美成人一区二区三区| 久久婷婷人人澡人人爽人人喊| 国产高清在线精品一区二区三区| 日本少妇高潮喷水xxxxxxx| 国产成人精品日本亚洲77上位| 尤物av无码国产在线看| 国产日韩在线观看不卡顿| 日本va在线视频播放| 99久久无码私人网站| 伊人久久成综合久久影院| 亚洲欧洲自偷自拍图片| 亚洲精品av一区午夜福利| 国产午夜片无码区在线播放| 99久久久无码国产精品试看| 久久精品国产99久久无毒不卡 | 精品一区二区三区影院在线午夜| 五月天天天综合精品无码| 黑人粗硬进入过程视频| 中文韩国午夜理伦三级好看| 亚洲精品tv久久久久久久久j| 初尝黑人嗷嗷叫中文字幕| 国产人妻人伦精品1国产丝袜 | 国产乱人伦偷精品视频免| 中文字幕人乱码中文| 性人久久久久| 国产在线精品一区二区在线看| 少妇人妻无码专区毛片|