在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ACTR2 Antibody

  • 中文名稱:
    ACTR2兔多克隆抗體
  • 貨號:
    CSB-PA001248ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA001248ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ACTR2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ACTR2
  • 別名:
    Actin like protein 2 antibody; Actin related protein 2 antibody; Actin-like protein 2 antibody; Actin-related protein 2 antibody; ACTR2 antibody; ARP2 actin related protein 2 homolog (yeast) antibody; ARP2 antibody; ARP2/3 COMPLEX antibody; ARP2_HUMAN antibody; OTTHUMP00000159937 antibody; OTTHUMP00000202270 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Actin-related protein 2 protein (1-160AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. In podocytes, required for the formation of lamellipodia downstream of AVIL and PLCE1 regulation. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
  • 基因功能參考文獻:
    1. We speculate that ACTR2 and MEIS1 might respectively play a role in the pathogenesis of the observed deafness and cardiomyopathy...the patient carrying a 2p14p15 deletion including OTX1 had normal kidneys and genitalia, thus confirming that OTX1 haploinsufficiency is not invariably associated with genitourinary defects. PMID: 28599093
    2. this study identified roles for ARP2 and filopodia in human respiratory syncytial virus -induced cell motility, virus production, and cell-to-cell spread. PMID: 27926942
    3. Coronin3 can regulate gastric cancer (GC) invasion and metastasis through Arp2, and the combination of Coronin3 and Arp2 provides a potential marker for predicting GC prognosis. PMID: 24918434
    4. Neural Wiskott-Aldrich syndrome protein (N-WASP)-mediated p120-catenin interaction with Arp2-Actin complex stabilizes endothelial adherens junctions. PMID: 23212915
    5. Using molecular dynamics simulations and biochemical assays with recombinant Arp2/3 complex, we now show how phosphorylation of Arp2 induces conformational changes permitting activation. PMID: 22125478
    6. ARP2-mediated actin polymerization is regulated by phosphorylation of WASP protein. PMID: 12791263
    7. Coexpression of Arp2 and WAVE2 is correlated with poorer patient outcome. PMID: 16638851
    8. High mRNA levels of Arp2 were significantly associated with liver metastasis of colorectal cancer. PMID: 17459058
    9. Arp2-depleted Jurkat T lymphocytes exhibit defects in spreading on anti-CD3; Arp2-depleted Jurkats exhibit defects in ruffle assembly but not in assembly of mitotic linear protrusions. PMID: 18720401

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Cell projection. Nucleus.
  • 蛋白家族:
    Actin family, ARP2 subfamily
  • 數據庫鏈接:

    HGNC: 169

    OMIM: 604221

    KEGG: hsa:10097

    STRING: 9606.ENSP00000367220

    UniGene: Hs.643727



主站蜘蛛池模板: 亚洲熟妇av一区二区三区宅男| 无码国内精品人妻少妇| 亚洲日韩看片无码电影| 成人av片在线观看免费| 在线视频观看免费视频18| 国产妇女馒头高清泬20p多毛| 亚洲精品国产嫩草在线观看东京热 | 国产真实夫妇视频| 国产av天堂无码一区二区三区| 免费观看四虎精品国产地址| 天堂最新版在线www官网中文地址 最新国产麻豆aⅴ精品无码 | 亚洲中文字幕不卡无码| 日韩久久久久久中文人妻| 在线视频网站www色| 日韩欧美中文字幕在线三区| 亚洲 一区二区 在线| 日韩人妻无码免费视频一区二区三区 | 国内露脸少妇精品视频| 国产69精品久久久久app下载| 午夜爱爱免费视频体验区| 免费做爰猛烈吃奶摸视频在线观看| 色两性网欧美| 天堂在线资源中文在线8| 一本清日本在线视频精品| 亚洲精品nv久久久久久久久久| аⅴ天堂中文在线网官网| 国产精品jk白丝在线播放| 综合亚洲综合图区网友自拍 | 久久久久四虎精品免费入口| 性欧美老妇另类xxxx| 国产97色在线 | 日韩| 2018亚洲а∨天堂| 日韩不卡1卡2卡三卡网站| 人妻精品无码一区二区三区| 日韩a无v码在线播放| 日日摸日日碰夜夜爽无| 色婷婷综合久久久中文字幕| 亚洲αⅴ无码乱码在线观看性色 | 伊人久久大香线蕉无码不卡| 精品久久久久久无码人妻热| 五月婷六月婷婷俺也去|