在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ACSL1 Antibody

ACSL1 Antibody

  • 中文名稱：
    ACSL1兔多克隆抗體
  • 貨號：
    CSB-PA001191GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    ACSL1; FACL1; FACL2; LACS; LACS1; LACS2; Long-chain-fatty-acid--CoA ligase 1; Acyl-CoA synthetase 1; ACS1; Arachidonate--CoA ligase; Long-chain acyl-CoA synthetase 1; LACS 1; Long-chain acyl-CoA synthetase 2; LACS 2; Long-chain fatty acid-CoA ligase 2; Palmitoyl-CoA ligase 1; Palmitoyl-CoA ligase 2; Phytanate--CoA ligase
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human ACSL1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate. Preferentially activates arachidonate than epoxyeicosatrienoic acids (EETs) or hydroxyeicosatrienoic acids (HETEs).
  • 基因功能參考文獻：
    1. These results suggest that ACSL1, ACSL4 and ACSL5 expression is regulated by ER signaling pathways and ACSL5 is a potential novel biomarker for predicting prognosis of breast cancer patients. PMID: 28498416
    2. Study identified a genetic variant in the 3'-UTR region of ACSL1 gene (rs8086) that may play a significant role in predicting outcomes of stage II/III patients with colon cancer, so that patients with T/T genotype had a significantly higher risk of tumor recurrence than those carrying at least one C allele. PMID: 27992526
    3. The mRNA levels of ACSL1 were positively associated with those of HBXIP in clinical breast cancer tissues. Thus, we conclude that the oncoprotein HBXIP is able to up-regulate ACSL1 through activating the transcriptional factor Sp1 in breast cancer. PMID: 28132807
    4. evidence in humans of ACSL1 SNPs associated with fasting glucose, diabetes, and subclinical atherosclerosis PMID: 26711138
    5. SRE motif in ACSL1 is essential for SREBP2-mediated activation of C-ACSL1 gene transcription. PMID: 26728456
    6. ACSL1 is a programmable mediator of insulin sensitivity and cellular lipid content. PMID: 25915184
    7. the cell surface protein CD36/FAT directly facilitates fatty acid transport across the plasma membrane, whereas the intracellular acyl-CoA synthetases FATP4 and ACSL1 enhance fatty acid uptake indirectly by metabolic trapping PMID: 24503477
    8. Data indicate that expression of miR-205 is negatively related to that of ACSL1 in clinical hepatocellular carcinoma (HCC) tissues. PMID: 24462768
    9. long-chain acyl-CoA synthetase 1 has a role in eicosapentaenoic acid suppression of palmitate-induced cytokine production PMID: 23433401
    10. Findings suggest that the ACSL1 gene polymorphism rs6552828 is not associated with elite endurance athletic status in Caucasians, yet a marginal association seems to exist for the Chinese (Han) male population. PMID: 22829935
    11. Data show that ACSL1 rs9997745 polymorphism influences metabolic syndrome risk, most likely via disturbances in fatty acid metabolism, which was modulated by dietary fat consumption, particularly PUFA intake, suggesting novel gene-nutrient interactions. PMID: 20176858
    12. Based on homology, two new isoforms for ACSL1 were predicted and characterized, one represented a switch of the Phe- to the Tyr-Gate domain motif, the other resulted from the exclusion of both. PMID: 16834775

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein.
  • 蛋白家族：
    ATP-dependent AMP-binding enzyme family
  • 組織特異性：
    Highly expressed in liver, heart, skeletal muscle, kidney and erythroid cells, and to a lesser extent in brain, lung, placenta and pancreas.
  • 數據庫鏈接：

    HGNC: 3569

    OMIM: 152425

    KEGG: hsa:2180

    STRING: 9606.ENSP00000281455

    UniGene: Hs.406678



主站蜘蛛池模板： 国产成人一区二区青青草原| 久久精品国产精品亚洲毛片 | 人妻精品久久无码区| 亚洲精品中文字幕久久久久下载| 一区二区三区av高清免费波多| 午夜福利伦伦电影理论片在线观看| 国产精品无码制服丝袜| 国产人妻人伦精品1国产| 亚洲人成无码网www电影榴莲 | 国产日韩欧美不卡在线二区| 东京无码熟妇人妻av在线网址| 少妇熟女视频一区二区三区 | 性欧美丰满熟妇xxxx性5| 人妻插b视频一区二区三区| 三级特黄60分钟在线播放| 扒开双腿吃奶呻吟做受视频| 日韩 欧美 国产 一区三| 天堂在线www资源在线| 性色欲情网站iwww九文堂| 99re8这里有精品热视频免费| 色综合视频一区二区三区| 成人爽a毛片免费网站| 强行征服邻居人妻淑敏| 国产精品人人做人人爽| 小sao货水好多真紧h无码视频| 午夜私人成年影院在线观看| 中文字幕人妻熟在线影院| 日本特黄特色aaa大片免费| 边添小泬边狠狠躁视频| 亚洲理论在线a中文字幕| 超清精品丝袜国产自在线拍| 久久久无码精品亚洲日韩按摩| 脱了美女内裤猛烈进入gif| 又爽又黄无遮拦成人网站| 无码人妻丝袜在线视频红杏| 露脸叫床粗话东北少妇| 亚洲熟妇色自偷自拍另类| 在线观看日本亚洲一区| 少妇极品熟妇人妻200片| 精品深夜av无码一区二区老年| 法国啄木乌av片在线播放|