在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯免疫試劑盒
  4. Human left-right determination factor 2(LEFTY2) ELISA Kit

Human left-right determination factor 2(LEFTY2) ELISA Kit

  • 中文名稱：
    人左右不對稱發育因子2(LEFTY2)酶聯免疫試劑盒
  • 貨號：
    CSB-E13590h
  • 規格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產品詳情

  • 產品描述：
    人左右不對稱發育因子2(LEFTY2)酶聯免疫試劑盒（CSB-E13590h）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿樣本中的LEFTY2含量。試劑盒檢測范圍為7.8 pg/mL-500 pg/mL，該產品適用于基礎科研領域，例如探究LEFTY2在胚胎發育異常、纖維化疾病或腫瘤發生發展中的分子機制，也可用于評估細胞模型或動物模型中LEFTY2的表達水平變化。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
  • 別名：
    EBAF ELISA Kit; Endometrial bleeding associated factor (left right determination factor A transforming growth factor beta superfamily) ELISA Kit; Endometrial bleeding associated factor ELISA Kit; Endometrial bleeding-associated factor ELISA Kit; Left right determination factor 2 ELISA Kit; Left right determination factor A ELISA Kit; Left-right determination factor 2 ELISA Kit; Left-right determination factor A ELISA Kit; LEFTA ELISA Kit; LEFTY 2 ELISA Kit; LEFTY2 ELISA Kit; LEFTYA ELISA Kit; LFTY2 transforming growth factor; beta -4 ELISA Kit; LFTY2; mouse; homolog of ELISA Kit; LFTY2_HUMAN ELISA Kit; MGC46222 ELISA Kit; Protein lefty 2 ELISA Kit; Protein lefty A ELISA Kit; Protein lefty-2 ELISA Kit; Protein lefty-A ELISA Kit; Protein lefty2 ELISA Kit; PSEC0024 ELISA Kit; TGF beta 4 ELISA Kit; TGF-beta-4 ELISA Kit; TGFB4 ELISA Kit; Transforming growth factor beta 4 ELISA Kit; Transforming growth factor beta-4 ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma
  • 檢測范圍：
    7.8 pg/mL-500 pg/mL
  • 靈敏度：
    1.95 pg/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Cancer
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human LEFTY2 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    　 Sample Serum(n=4)
    1:100 Average % 91
    Range % 86-95
    1:200 Average % 102
    Range % 97-107
    1:400 Average % 91
    Range % 85-97
    1:800 Average % 97
    Range % 91-103
  • 回收率：
    The recovery of human LEFTY2 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample Type Average % Recovery Range
    Serum (n=5) 95 89-98
    EDTA plasma (n=4) 97 90-100
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/ml OD1 OD2 Average Corrected
    500 2.811 2.836 2.824 2.744
    250 2.038 2.000 2.019 1.939
    125 1.331 1.368 1.350 1.270
    62.5 0.804 0.752 0.778 0.698
    31.2 0.473 0.498 0.486 0.406
    15.6 0.278 0.281 0.280 0.200
    7.8 0.173 0.169 0.171 0.091
    0 0.079 0.081 0.080 　
  • 數據處理：
  • 貨期：
    3-5 working days

產品評價

靶點詳情

  • 功能：
    Required for left-right (L-R) asymmetry determination of organ systems in mammals. May play a role in endometrial bleeding.
  • 基因功能參考文獻：
    1. functional role of LEFTY during progesterone therapy for endometrial carcinoma PMID: 29268772
    2. LeftyA leads to disruption of Rac1 and Pak1 activity with subsequent actin depolymerization, cell softening and cell shrinkage. PMID: 27404958
    3. LEFTY2 down-regulates MKi67 expression and FAK activity, up-regulates miR-200a and E-cadherin, and is thus a powerful negative regulator of endometrial cell proliferation and migration. PMID: 27497669
    4. LEFTY2 regulates the expression and activity of ENaC in endometrial epithelial cells via SGK1. PMID: 27606670
    5. Lefty A may account for the tumor suppressive activity of human adult stem cells. PMID: 22469982
    6. Findings suggest that Lefty2 is negatively modulated by miR-302s in hESCs, which plays an important role in maintaining the balance between pluripotency and germ layer specification. PMID: 21266536
    7. Findings show that during embryonic development, EBAF/LEFTY B plays important roles in decidualization and embryo implantation. PMID: 21401636
    8. findings show that the TGFB4 (ebaf) mRNA has distinct tumor specific expression PMID: 9230066
    9. may provide a crucial signal for endometrial breakdown and bleeding by triggering expression of several matrix metalloproteinases PMID: 12215426
    10. nodal and the inhibitors of Nodal signaling, lefty-A and lefty-B, are down-regulated very early upon differentiation of human embryonic stem cells PMID: 15308665
    11. Addition of recombinant LEFTY-A to explants induced MMP-9 in most samples, a response prevented by ovarian steroids. PMID: 15536155
    12. LEFTY proteins, which are known to play a major role during mouse gastrulation, are transiently expressed during human embryonic stem cell differentiation. PMID: 17038673

    顯示更多

    收起更多

  • 相關疾病：
    Left-right axis malformations (LRAM)
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    TGF-beta family
  • 組織特異性：
    Mesenchymal cells of the endometrial stroma.
  • 數據庫鏈接：

    HGNC: 3122

    OMIM: 601877

    KEGG: hsa:7044

    STRING: 9606.ENSP00000355785

    UniGene: Hs.520187



主站蜘蛛池模板： 精品 在线 视频 亚洲| 成人精品免费视频在线观看| 蜜臀av色欲a片无人一区| 久久精品女同亚洲女同| 亚洲成a人片在线观看无码| 我的公把我弄高潮了视频| 大乳丰满人妻中文字幕日本电影| 国产日韩亚洲大尺度高清 | 激情国产一区二区三区四区| 国产午夜成人久久无码一区二区| 久久久老熟女一区二区三区| 中文字幕人妻无码专区| 无码中文字幕波多野结衣| 国产成人精品手机在线观看| 久久久久成人网站| 成人毛片无码免费播放网站| 亚洲高清专区日韩精品| 国产av亚洲精品久久久久久小说| 国产熟妇按摩3p高潮大叫| 娇妻被黑人粗大高潮白浆| 国产精品无码av在线一区| 人人妻人人澡人人爽偷拍台湾| 麻豆成人精品国产免费| 亚洲最大无码中文字幕| 国产成人综合95精品视频| h人成在线看免费视频| 熟女性饥渴一区二区三区| 狠狠色狠狠色综合久久| 超级碰97直线国产免费公开| 美女18禁一区二区三区视频| 无套内射在线无码播放| 亚洲夜色噜噜av在线观看| 国产精品久久人妻互换| 小宝极品内射国产在线| 在线播放五十路熟妇| 国产在线无码制服丝袜无码 | 香蕉噜噜噜噜私人影院| 亚洲色素色无码专区| 2019nv天堂香蕉在线观看| 天天爽夜夜爽夜夜爽| 久久久久人妻精品区一三寸|