在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse C-X-C motif chemokine 11 protein (Cxcl11)

In Stock
  • 中文名稱:
    Recombinant Mouse C-X-C motif chemokine 11 protein(Cxcl11) (Active)
  • 貨號(hào):
    CSB-AP001151MO
  • 規(guī)格:
    ¥852
  • 圖片:
  • 其他:

產(chǎn)品詳情

  • 純度:
    >98% as determined by SDS-PAGE.
  • 內(nèi)毒素:
    Less than 1.0 EU/μg as determined by LAL method.
  • 生物活性:
    Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine CXCR3 transfected 293 cells is in a concentration of 10-100 ng/ml.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Cxcl11; Scyb11C-X-C motif chemokine 11; Interferon-inducible T-cell alpha chemoattractant; I-TAC; Small-inducible cytokine B11
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度:
    Full Length of Mature Protein
  • 來(lái)源:
    E.Coli
  • 分子量:
    9.1 kDa
  • 表達(dá)區(qū)域:
    22-100aa
  • 氨基酸序列
    FLMFKQGRCL CIGPGMKAVK MAEIEKASVI YPSNGCDKVE VIVTMKAHKR QRCLDPRSKQ ARLIMQAIEK KNFLRRQNM
  • 蛋白標(biāo)簽:
    Tag-Free
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    0.2 μm filtered PBS, pH 7.4 ,lyophilized
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    5-10 business days
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
  • 基因功能參考文獻(xiàn):
    1. although the expression of CXCL9 and CXCL11 are increased after spinal nerve ligation, they may not contribute to the maintenance of neuropathic pain. PMID: 29712506
    2. These findings functionally integrate K17, hnRNP K, and gene expression along with RSK and CXCR3 signaling in a keratinocyte-autonomous axis and provide a potential basis for their implication in tumorigenesis PMID: 25713416
    3. very low doses of CXCL11 rapidly suppress signs of EAE in C57BL/6 mice lacking functional CXCL11. PMID: 24713654
    4. Data indicate that epidermis-derived I-TAC (Cxcl11) triggers a sustained Th2-response that determines the outcome of a complex immunological process. PMID: 24398292
    5. Analysis of genes within the Listr1 locus identified a frameshift mutation in the Cxcl11 gene of the C57BL/6 strain that prevents production of the mature chemokine CXCL11. PMID: 24566892
    6. Cxcl10 and cxcl11 are new hair-specific transcriptional targets of ectodysplasin, and they indicates involvement of chemokines in hair development. PMID: 22277947
    7. the CXCL11-heparin interaction has two different affinities for glycosaminoglycans PMID: 20363748
    8. I-TAC can have an important role during virus infections and vaccinia virus has evolved ways to avoid inducing I-TAC expression. PMID: 15030574
    9. I-TAC acts as an antagonist for CCR5. I-TAC inhibited the binding of macrophage-inflammatory protein-1alpha (MIP-1alpha)/CC chemokine ligand 3 (CCL3) to cells transfected with CCR5 and to monocytes. PMID: 15178708
    10. Acute ethanol intoxication impairs lung expression of Cxcl11, interfering with pulmonary response to bacterial challenge. PMID: 17889309
    11. homologous to human T cell attracting chemokine CXC receptor ligand 11; involved in calcium mobilization and chemotaxis PMID: 11500837

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    Intercrine alpha (chemokine CxC) family
  • 數(shù)據(jù)庫(kù)鏈接:

    KEGG: mmu:56066

    UniGene: Mm.131723



主站蜘蛛池模板: 亚洲精品国偷自产在线99人热| 亚洲va无码va在线va天堂| 99视频有精品视频高清| 国产综合18久久久久久| 西西人体www44rt大胆高清| 欧美人与动牲交aⅴ| 亚洲 欧美 国产 日韩 中文字幕| 人妻换人妻仑乱| 亚洲成av人片天堂网久久| 99久久伊人精品综合观看| 领导边摸边吃奶边做爽在线观看| 永久免费看mv网站入口亚洲| 精品国产乱码久久久久软件| 久久视频在线视频精品| 久久久久亚洲精品成人网| 日日噜噜夜夜爽爽| 精品熟女少妇a∨免费久久| 国产一卡2卡3卡四卡精品国色无边| 无码中文字幕乱在线观看| 精品无码国产av一区二区| 欧美18精品久久久无码午夜福利| 午夜视频在线观看免费完整版| 艳妇荡女欲乱双飞两中年熟妇| 强睡邻居人妻中文字幕| 亚洲精品卡2卡3卡4卡5卡区| 天天天天噜在线视频| 激情综合一区二区三区| 成 人影片 免费观看| 人妻avav中文系列久久| 无码人妻久久一区二区三区app| 日韩欧美在线综合网另类| 色窝窝无码一区二区三区| 狠狠久久久久综合成人影院 | 国产男女猛烈无遮挡a片漫画| 欧美高清性色生活片免费观看| 中文字幕人妻av一区二区| 涩欲国产一区二区三区四区| 国产成人精品亚洲日本在线观看| 欧美精品亚洲精品日韩专区va| 少妇被又大又粗又爽毛片| 久久国产精品久久精品国产|