在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse C-X-C motif chemokine 11 protein (Cxcl11)

In Stock
  • 中文名稱:
    Recombinant Mouse C-X-C motif chemokine 11 protein(Cxcl11) (Active)
  • 貨號(hào):
    CSB-AP001151MO
  • 規(guī)格:
    ¥852
  • 圖片:
  • 其他:

產(chǎn)品詳情

  • 純度:
    >98% as determined by SDS-PAGE.
  • 內(nèi)毒素:
    Less than 1.0 EU/μg as determined by LAL method.
  • 生物活性:
    Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine CXCR3 transfected 293 cells is in a concentration of 10-100 ng/ml.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Cxcl11; Scyb11C-X-C motif chemokine 11; Interferon-inducible T-cell alpha chemoattractant; I-TAC; Small-inducible cytokine B11
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度:
    Full Length of Mature Protein
  • 來(lái)源:
    E.Coli
  • 分子量:
    9.1 kDa
  • 表達(dá)區(qū)域:
    22-100aa
  • 氨基酸序列
    FLMFKQGRCL CIGPGMKAVK MAEIEKASVI YPSNGCDKVE VIVTMKAHKR QRCLDPRSKQ ARLIMQAIEK KNFLRRQNM
  • 蛋白標(biāo)簽:
    Tag-Free
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    0.2 μm filtered PBS, pH 7.4 ,lyophilized
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    5-10 business days
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
  • 基因功能參考文獻(xiàn):
    1. although the expression of CXCL9 and CXCL11 are increased after spinal nerve ligation, they may not contribute to the maintenance of neuropathic pain. PMID: 29712506
    2. These findings functionally integrate K17, hnRNP K, and gene expression along with RSK and CXCR3 signaling in a keratinocyte-autonomous axis and provide a potential basis for their implication in tumorigenesis PMID: 25713416
    3. very low doses of CXCL11 rapidly suppress signs of EAE in C57BL/6 mice lacking functional CXCL11. PMID: 24713654
    4. Data indicate that epidermis-derived I-TAC (Cxcl11) triggers a sustained Th2-response that determines the outcome of a complex immunological process. PMID: 24398292
    5. Analysis of genes within the Listr1 locus identified a frameshift mutation in the Cxcl11 gene of the C57BL/6 strain that prevents production of the mature chemokine CXCL11. PMID: 24566892
    6. Cxcl10 and cxcl11 are new hair-specific transcriptional targets of ectodysplasin, and they indicates involvement of chemokines in hair development. PMID: 22277947
    7. the CXCL11-heparin interaction has two different affinities for glycosaminoglycans PMID: 20363748
    8. I-TAC can have an important role during virus infections and vaccinia virus has evolved ways to avoid inducing I-TAC expression. PMID: 15030574
    9. I-TAC acts as an antagonist for CCR5. I-TAC inhibited the binding of macrophage-inflammatory protein-1alpha (MIP-1alpha)/CC chemokine ligand 3 (CCL3) to cells transfected with CCR5 and to monocytes. PMID: 15178708
    10. Acute ethanol intoxication impairs lung expression of Cxcl11, interfering with pulmonary response to bacterial challenge. PMID: 17889309
    11. homologous to human T cell attracting chemokine CXC receptor ligand 11; involved in calcium mobilization and chemotaxis PMID: 11500837

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    Intercrine alpha (chemokine CxC) family
  • 數(shù)據(jù)庫(kù)鏈接:

    KEGG: mmu:56066

    UniGene: Mm.131723



主站蜘蛛池模板: 国产白嫩护士被弄高潮| 欧美日韩亚洲精品瑜伽裤| 久久午夜神器| 午夜dv内射一区区| 精品人妻av区乱码| 欧美人与动牲交xxxxbbbb| 在线中文新版最新版在线 | 免费看国产精品3a黄的视频| 国产欧美成人xxx视频| 无码精品国产一区二区免费 | 无码人妻视频一区二区三区| 人与狗精品aa毛片| 丁香五月缴情在线| 国产福利姬喷水福利在线观看 | 日韩免费码中文在线观看| 在线视频免费无码专区| 2020精品国产自在现线官网 | 亚洲欧美日韩愉拍自拍美利坚| yyyy11111少妇影院| 国产未成女一区二区| 中文字幕资源网| 亚洲中文字幕无码爆乳av| 亚洲久热无码av中文字幕| 国产免费观看黄av片| 天堂а√在线最新版中文| 亚洲国产精品一区二区制服| 欧美黑人又粗又大久久久| 中文字幕无码第1页| 波多野结衣av无码| 国产精品白浆在线观看免费| 成人夜色视频网站在线观看| 亚洲国产三级在线观看| 亚洲人成影院在线观看| 精品三级av无码一区| 国产 高清 无码 在线播放| 国产在线98福利播放视频| 性xxxx18免费观看视频| 日韩人妻熟女中文字幕a美景之屋 高h纯肉无码视频在线观看 | 在线观看片免费视频无码| 天美麻花果冻视频大全英文版| 97人妻人人做人碰人人爽|