SLC1A4
SLC1A4,全名為溶質載體家族1成員4(Solute Carrier Family 1 Member 4),常見別名為ASCT1和谷氨酰胺轉運蛋白1(GLT-1)。該蛋白主要參與中性氨基酸,特別是谷氨酰胺的跨膜轉運,在神經系統中發揮著重要作用。SLC1A4蛋白通過鈉離子依賴的方式,將谷氨酰胺從細胞外轉運至細胞內,為神經遞質合成提供必需的前體物質。這一過程對神經元的正常功能至關重要,與學習、記憶和神經發育密切相關。此外,SLC1A4蛋白的表達和功能異常與多種疾病相關,包括癌癥、神經退行性疾病和代謝性疾病。在癌癥中,SLC1A4蛋白的表達水平常與腫瘤的生長和轉移密切相關,成為潛在的藥物靶點。目前,針對SLC1A4蛋白的藥物研發已取得一定進展,例如小核酸藥物和靶向抑制劑等,為相關疾病的治療提供了新的策略。
熱銷產品
SLC1A4 Antibody (CSB-PA281969)
驗證數據

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA281969(SLC1A4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)

Gel: 10+12%SDS-PAGE, Lysate: 30 μg, Lane: Human liver cancer tissue, Primary antibody: CSB-PA281969(SLC1A4 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
SLC1A4 Antibodies
SLC1A4 for Homo sapiens (Human)
產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
---|---|---|---|
CSB-PA021435GA01HU | SLC1A4 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA281969 | SLC1A4 Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA443704 | SLC1A4 Antibody | Human,Mouse | ELISA,WB,IHC |
SLC1A4 Proteins
SLC1A4 Proteins for Homo sapiens (Human)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP021435HU CSB-EP021435HU CSB-BP021435HU CSB-MP021435HU CSB-EP021435HU-B |
Recombinant Human Neutral amino acid transporter A (SLC1A4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |