在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLC1A4 Antibody

  • 中文名稱:
    SLC1A4兔多克隆抗體
  • 貨號:
    CSB-PA281969
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA281969(SLC1A4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 10+12%SDS-PAGE, Lysate: 30 μg, Lane: Human liver cancer tissue, Primary antibody: CSB-PA281969(SLC1A4 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Alanine/serine/cysteine/threonine transporter 1 antibody; ASCT-1 antibody; ASCT1 antibody; AW045657 antibody; Glutamate/neutral amino acid transporter antibody; Neutral amino acid transporter A antibody; OTTHUMP00000159933 antibody; OTTHUMP00000235138 antibody; SATT antibody; SATT_HUMAN antibody; SLC1A4 antibody; Solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 antibody; Solute carrier family 1 member 4 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthetic peptide of Human SLC1A4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence.
  • 基因功能參考文獻:
    1. Results suggest that ASCT1/2 may play an important role in regulating extracellular d-serine and NMDA receptor-mediated physiological effects and that ASCT1/2 inhibitors have the potential for therapeutic benefit. PMID: 28807674
    2. ANKRD50 simultaneously engages multiple parts of the SNX27-retromer-WASH complex machinery in a direct and co-operative interaction network that is needed to efficiently recycle the nutrient transporters PMID: 27909246
    3. SLC1A4 deficiency should not be considered a population-specific disorder, and all patients with unexplained severe neurodevelopmental delay and the features outlined should be investigated regardless of ethnicity, as there are no known metabolic markers of this potentially treatable condition. PMID: 27193218
    4. SLC1A4 is the disease causing gene of a novel neurologic disorder manifesting with significant intellectual disability, severe postnatal microcephaly, spasticity and thin corpus callosum. PMID: 26138499
    5. ASCT1 is essential in brain serine transport. PMID: 26041762
    6. SLC1A4 disruption may impair brain development and function by decreasing the levels of L-serine in neurons. The identification of additional families with mutations in SLC1A4 would be necessary to confirm its involvement in intellectual disability. PMID: 25930971
    7. Na+ interactions with the neutral amino acid transporter ASCT1. PMID: 24808181
    8. ASCT1 is able to mediate a concentrative transport of alanine, which is Na+-dependent but not coupled to the Na+ gradient PMID: 11824937
    9. used as receptor by HERV-W Env glycoprotein PMID: 12050356
    10. results strongly suggest that combinations of amino acid sequence changes and N-linked oligosaccharides in a critical carboxyl-terminal region of extracellular loop 2 (ECL2) control retroviral utilization of both the ASCT1 and ASCT2 receptors PMID: 12584318
    11. This study revealed genetic associations of SLC1A4, SQSTM1, and EIF4EBP1 with MSA. These results may lend genetic support to the hypothesis that oxidative stress is associated with the pathogenesis of MSA. PMID: 18442140
    12. SLC1A4 gene is associated with schizophrenia. PMID: 18638388

    顯示更多

    收起更多

  • 相關疾病:
    Spastic tetraplegia, thin corpus callosum, and progressive microcephaly (SPATCCM)
  • 亞細胞定位:
    Membrane; Multi-pass membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • 蛋白家族:
    Dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family, SLC1A4 subfamily
  • 組織特異性:
    Expressed mostly in brain, muscle, and pancreas but detected in all tissues examined.
  • 數據庫鏈接:

    HGNC: 10942

    OMIM: 600229

    KEGG: hsa:6509

    STRING: 9606.ENSP00000234256

    UniGene: Hs.654352



主站蜘蛛池模板: 精品久久久噜噜噜久久久| 韩国无码av片在线观看网站| 国产无遮挡又黄又爽免费视频| 黑人大群体交免费视频| 国产精品亚洲片在线观看不卡| 大香伊蕉在人线免费视频| 波多野结衣潮喷视频无码42| 精品亚洲国产成人av| 日韩久久无码免费毛片软件| 婷婷俺也去俺也去官网| 2021自拍偷在线精品自拍偷 | 51视频国产精品一区二区| 永久免费男同av无码入口| 国产成人8x人网站在线视频| 色翁荡熄又大又硬又粗又动态图| 国产乱码人妻一区二区三区四区| 亚洲综合在线视频自拍| 中文字幕亚洲码在线| 欧美人与动性xxxxx杂性| 久久久天堂国产精品女人| 欧美精品1卡二卡三卡四卡| 又嫩又硬又黄又爽的视频| 午夜成人理论福利片| 四虎亚洲精品成人a在线观看| 国产成人精品999视频| 少妇高潮av久久久久久| 国产亚洲精品久久久ai换| 极品国产主播粉嫩在线| 一本加勒比hezyo无码专区| 少妇高潮惨叫久久久久久| 伊人精品一本久久综合| 精品国产在天天在线观看| 无码国产色欲xxxx视频| 亚洲中文字幕婷婷在线| 亚洲伊人成无码综合影院| 欧洲熟妇色xxxx欧美老妇多毛| 国产精品-区区久久久狼| 久久精品私人影院免费看| 特大黑人娇小亚洲女| 国产无遮挡无码视频免费软件| 国产精品69人妻无码久久|