RNASEH1
RNASEH1(Ribonuclease H1)是核糖核酸內(nèi)切酶H1內(nèi)切酶。RNASEH1的主要功能是在DNA修復過程中起作用,特別是在RNA-DNA雜交物的剪切中。它有助于維持基因組穩(wěn)定性,通過消除RNA與DNA的雜交,防止不必要的雜交結構的累積,并保持細胞的正常功能。研究表明,RNASEH1的突變或缺陷與一種罕見的遺傳性神經(jīng)系統(tǒng)退行性疾病——Aicardi-Goutières綜合征(AGS)相關。AGS通常伴隨著神經(jīng)系統(tǒng)發(fā)育異常和免疫系統(tǒng)異常,而RNASEH1的異??赡芘c此類癥狀的出現(xiàn)有關。此外,RNASEH1在細胞生物學研究和RNA-DNA雜交相關領域也具有重要的應用潛力。對RNASEH1的深入研究不僅有助于理解細胞的核酸代謝和基因組穩(wěn)定性的維持,還可能為治療相關疾病提供新的治療方法或干預手段。
熱銷產(chǎn)品
Recombinant Human Ribonuclease H1 (RNASEH1)
驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP019801HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) RNASEH1.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP019801HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) RNASEH1.
RNASEH1 Antibodies
RNASEH1 for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
---|---|---|---|
CSB-PA019801GA01HU | RNASEH1 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA019801LA01HU | RNASEH1 Antibody | Human | ELISA, WB, IHC |
CSB-PA019801LB01HU | RNASEH1 Antibody, HRP conjugated | Human | ELISA |
CSB-PA019801LC01HU | RNASEH1 Antibody, FITC conjugated | Human | |
CSB-PA019801LD01HU | RNASEH1 Antibody, Biotin conjugated | Human | ELISA |
RNASEH1 Proteins
RNASEH1 Proteins for Mus musculus (Mouse)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP019801MO CSB-EP019801MO CSB-BP019801MO CSB-MP019801MO CSB-EP019801MO-B |
Recombinant Mouse Ribonuclease H1 (Rnaseh1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RNASEH1 Proteins for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP019801HU CSB-BP019801HU CSB-MP019801HU CSB-EP019801HU-B |
Recombinant Human Ribonuclease H1 (RNASEH1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP019801HU | Recombinant Human Ribonuclease H1 (RNASEH1) | E.coli |
CSB-EP019801HUc7 | Recombinant Human Ribonuclease H1 (RNASEH1) | E.coli |