在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PLAUR

尿激酶型纖溶酶原激活物受體(PLAUR,又稱uPAR或CD87)是一種錨定于細胞膜表面的糖蛋白受體,其核心功能是通過與尿激酶(uPA)結合,激活纖溶酶原轉化為纖溶酶,進而觸發細胞外基質降解酶類的級聯反應。這一過程在組織重塑、傷口愈合中起關鍵作用,但也被發現與惡性腫瘤的侵襲轉移密切相關。臨床研究顯示,PLAUR在乳腺癌、結直腸癌等多種實體瘤中高表達,其水平升高常提示患者預后不良。該受體還能與整合素等跨膜蛋白協同調控細胞遷移,參與動脈粥樣硬化斑塊形成及類風濕性關節炎的病理進程。
近年來針對PLAUR的藥物開發聚焦于阻斷uPA-uPAR相互作用,例如單抗類藥物ATN-658已在動物模型中顯著抑制腫瘤轉移。小分子抑制劑如upain-1通過干擾受體二聚化降低癌細胞侵襲能力,目前處于臨床前研究階段。部分聯合治療方案嘗試將uPAR靶向藥物與傳統化療聯用,初步數據顯示可增強抗腫瘤效果并減少耐藥性,但尚未進入三期臨床試驗。

熱銷產品

Recombinant Human Urokinase plasminogen activator surface receptor (PLAUR) (CSB-EP018122HU)

驗證數據

CSB-EP018122HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PLAUR Recombinant Monoclonal Antibody (CSB-RA018122MA1HU)

驗證數據

CSB-RA018122MA1HU

Immunofluorescence staining of hela cell with CSB-RA018122MA1HU at 1:30, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Mouse IgG(H+L).

CSB-RA018122MA1HU

Immunofluorescence staining of SH-SY5Y cell with CSB-RA018122MA1HU at 1:30, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Mouse IgG(H+L).

CSB-RA018122MA1HU

Overlay Peak curve showing Hela cells surface stained with CSB-RA018122MA1HU (red line) at 1:100. Then 10% normal goat serum was Incubated to block non-specific protein-protein interactions followed by the antibody (1μg/1*106cells) for 45 min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-Mouse IgG(H+L) at 1/200 dilution for 35 min at 4°C. Isotype control antibody (green line) was mouse IgG1 (1μg/1*106cells) used under the same conditions. Acquisition of >10,026 events was performed.

PLAUR Antibodies

PLAUR for Rattus norvegicus (Rat)

PLAUR for Homo sapiens (Human)

PLAUR Proteins

PLAUR Proteins for Homo sapiens (Human)

PLAUR Proteins for Mus musculus (Mouse)

PLAUR Proteins for Rattus norvegicus (Rat)

PLAUR Proteins for Bos taurus (Bovine)

PLAUR Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

PLAUR Proteins for Aotus trivirgatus (Night monkey) (Douroucouli)

PLAUR Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

PLAUR Proteins for Pan troglodytes (Chimpanzee)

PLAUR ELISA Kit

PLAUR ELISA Kit for Homo sapiens (Human)

PLAUR ELISA Kit for Rattus norvegicus (Rat)



主站蜘蛛池模板: 51国产黑色丝袜高跟鞋| 豆国产97在线 | 亚洲| аⅴ资源中文在线天堂| 激情五月婷婷| 男人和女人高潮免费网站| 三男一女吃奶添下面视频| 久久综合狠狠色综合伊人| 国产激情综合五月久久| 亚洲国产精品一区二区久久| 免费刺激性视频大片区| 日本欧美大码a在线观看| 久久人妻少妇嫩草av蜜桃| 国产精品美脚玉足脚交欧美| 久久男人av资源站| 国产精品鲁鲁鲁| 久久三级中文欧大战字幕| 久久久久四虎精品免费入口| 中文字幕有码无码人妻在线| 亚洲国产制服丝袜高清在线| 日韩~欧美一中文字幕| 欧美日韩国产综合新一区| 亚洲最大成人av在线天堂网| 欧美黑人xxxx高潮猛交| 隔壁人妻偷人bd中字| 国产乱妇无乱码大黄aa片| 大肉大捧一进一出好爽app| av无码免费岛国动作片片段欣赏网| 人妻熟女av一区二区三区 | 久久精品囯产精品亚洲| 天天躁日日躁狠狠躁性色av| 精品国产中文字幕在线视频| 日韩亚洲国产高清免费视频| 亚洲精品久久久www小说| 99精品视频在线观看免费| 免费吃奶摸下激烈视频| 久久综合五月丁香六月丁香| 综合色区亚洲熟妇另类| 久久久久久亚洲精品成人| 成人电线在线播放无码| 免费午夜理论不卡| 婷婷网色偷偷亚洲男人甘肃|