ODC
ODC(鳥氨酸脫羧酶)是一種關鍵酶,它催化鳥氨酸脫羧生成腐胺,這是多胺合成的重要步驟。ODC由461個氨基酸組成,形成同源二聚體結構,并在細胞內以單體和二聚體形式迅速轉換。作為細胞生長所必需的酶,ODC通過產生多胺來穩定新合成的DNA,對DNA結構穩定、DNA雙鏈斷裂修復以及抗氧化等方面都具有重要作用。盡管ODC本身不直接參與特定的信號通路,但其在細胞生長和多胺合成中的核心作用可能對某些信號通路產生間接影響,如通過調控Akt/GSK3β/β-catenin等信號通路影響肝癌細胞的增殖、侵襲和遷移等過程。
熱銷產品
Recombinant Human Ornithine decarboxylase (ODC1) (CSB-EP016269HU)
驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP016269HU could indicate that this peptide derived from E.coli-expressed Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) ODC1 .

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP016269HU could indicate that this peptide derived from E.coli-expressed Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) ODC1 .
ODC Antibodies
ODC for Homo sapiens (Human)
產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
---|---|---|---|
CSB-PA00535A0Rb | ODC1 Antibody | Human | ELISA, WB, IHC, IF |
CSB-PA016269GA01HU | ODC1 Antibody | Human,Mouse,Rat | ELISA,IF |
CSB-PA00535D0Rb | ODC1 Antibody, Biotin conjugated | Human | ELISA |
CSB-PA546739 | ODC1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA818178 | ODC1 Antibody | Human,Mouse,Rat | ELISA,IHC |
ODC Proteins
ODC Proteins for Homo sapiens (Human)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP016269HU CSB-BP016269HU CSB-MP016269HU CSB-EP016269HU-B |
Recombinant Human Ornithine decarboxylase (ODC1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP016269HU | Recombinant Human Ornithine decarboxylase (ODC1) | E.coli |