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NAIP

Baculoviral IAP repeat-containing protein 1 is a protein in humans that is encoded by NAIP gene. Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasing the rate of auto proteolysis at 'Asp-330'. Acts as a mediator of neuronal survival in pathological conditions. Prevents motor-neuron apoptosis induced by a variety of signals. Possible role in the prevention of spinal muscular atrophy that seems to be caused by inappropriate persistence of motor-neuron apoptosis.

NAIP Antibodies

NAIP for Homo sapiens (Human)

NAIP Proteins

NAIP Proteins for Bacillus subtilis (strain 168)

NAIP Proteins for Homo sapiens (Human)