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MYO10

Unconventional myosin-X is a protein in humans that is encoded by MYO10 gene. Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. In hippocampal neurons it induces the formation of dendritic filopodia by trafficking the actin-remodeling protein VASP to the tips of filopodia, where it promotes actin elongation. Plays a role in formation of the podosome belt in osteoclasts.

MYO10 Antibodies

MYO10 for Homo sapiens (Human)

MYO10 Proteins

MYO10 Proteins for Bos taurus (Bovine)

MYO10 Proteins for Rattus norvegicus (Rat)

MYO10 Proteins for Mus musculus (Mouse)

MYO10 Proteins for Homo sapiens (Human)



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