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MCM5

DNA replication licensing factor MCM5 is a protein in humans that is encoded by MCM5 gene. Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.

MCM5 Antibodies

MCM5 for Homo sapiens (Human)

MCM5 Proteins

MCM5 Proteins for Homo sapiens (Human)

MCM5 Proteins for Mus musculus (Mouse)

MCM5 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

MCM5 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

MCM5 Proteins for Bos taurus (Bovine)

MCM5 Proteins for Dictyostelium discoideum (Slime mold)

MCM5 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

MCM5 Proteins for Drosophila melanogaster (Fruit fly)



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