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HCRTR1

HCRTR1,即下丘腦神經(jīng)肽orexin受體1,別名Ox1-R。攝食行為、睡眠-覺醒周期、應(yīng)激反應(yīng)等多種生理功能相關(guān)。HCRTR1的作用機(jī)制是通過與下丘腦神經(jīng)肽orexin A的結(jié)合,激活G蛋白偶聯(lián)的信號傳導(dǎo)途徑,影響下游的細(xì)胞內(nèi)信號級聯(lián)反應(yīng)。HCRTR1在調(diào)節(jié)睡眠、覺醒、能量代謝以及對應(yīng)激的響應(yīng)等方面發(fā)揮重要作用。此外,HCRTR1的功能異常與多種疾病相關(guān),包括失眠、嗜睡癥、肥胖等,因此它也是藥物開發(fā)中的潛在靶點(diǎn)。

熱銷產(chǎn)品

Recombinant Human Orexin/Hypocretin receptor type 1 (HCRTR1), partial (CSB-YP010231HU1)

驗(yàn)證數(shù)據(jù)

CSB-YP010231HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

HCRTR1 Antibody (CSB-PA797469)

驗(yàn)證數(shù)據(jù)

CSB-PA797469

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA797469(HCRTR1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA797469

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA797469(HCRTR1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)

HCRTR1 Antibodies

HCRTR1 for Homo sapiens (Human)

HCRTR1 Proteins

HCRTR1 Proteins for Mus musculus (Mouse)

HCRTR1 Proteins for Rattus norvegicus (Rat)

HCRTR1 Proteins for Sus scrofa (Pig)

HCRTR1 Proteins for Bos taurus (Bovine)

HCRTR1 Proteins for Homo sapiens (Human)