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GRK5

G protein-coupled receptor kinase 5 is a protein in humans that is encoded by GRK5 gene. Serine/threonine kinase that phosphorylates preferentially the activated forms of a variety of G-protein-coupled receptors (GPCRs). Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation. Phosphorylates a variety of GPCRs, including adrenergic receptors, muscarinic acetylcholine receptors (more specifically Gi-coupled M2/M4 subtypes), dopamine receptors and opioid receptors. In addition to GPCRs, also phosphorylates various substrates.

GRK5 Antibodies

GRK5 for Homo sapiens (Human)

GRK5 Proteins

GRK5 Proteins for Homo sapiens (Human)

GRK5 Proteins for Bos taurus (Bovine)

GRK5 Proteins for Rattus norvegicus (Rat)

GRK5 Proteins for Mus musculus (Mouse)