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GDF15

GDF15,即生長分化因子15,別名包括MIC-1、PDF等,是TGFβ超家族的一員。它作為應(yīng)激反應(yīng)蛋白,在多種疾病中扮演關(guān)鍵角色。GDF15通過與GFRAL-RET受體結(jié)合,調(diào)控食欲、體重、胰島素敏感性及炎癥反應(yīng)等生理過程。其水平升高常見于腫瘤、心血管疾病及代謝性疾病,不僅是這些疾病的潛在生物標(biāo)志物,也是藥物研發(fā)的新靶點(diǎn)。目前,GDF15靶向療法正成為研究熱點(diǎn),旨在通過調(diào)節(jié)GDF15水平,為相關(guān)疾病的治療提供新的策略和方法。

熱銷產(chǎn)品

Recombinant Human Growth/differentiation factor 15 (GDF15), partial (CSB-EP859530HU)

驗(yàn)證數(shù)據(jù)

CSB-EP859530HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

GDF15 Recombinant Monoclonal Antibody (CSB-RA285852A0HU)

驗(yàn)證數(shù)據(jù)

CSB-RA285852A0HU

IHC image of CSB-RA285852A0HU diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

GDF15 Antibodies

GDF15 for Homo sapiens (Human)

GDF15 Proteins

GDF15 Proteins for Homo sapiens (Human)

GDF15 ELISA Kit

GDF15 ELISA Kit for Homo sapiens (Human)

GDF15 ELISA Kit for Mus musculus (Mouse)

GDF15 ELISA Kit for Rattus norvegicus (Rat)