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Your Good Partner in Biology Research

CD81

CD81是一種四次跨膜蛋白,屬于跨膜家族(TM4SF)的成員。擁有一個大的胞外親水環,這個環包含兩個半胱氨酸殘基,可以形成二硫鍵,對維持其結構穩定具有重要作用。此外,CD81的胞內區域較短,含有多個可能的磷酸化位點,這些位點參與信號轉導過程。CD81的異常表達或功能失調與多種疾病的發生和發展有關。例如,在丙型肝炎病毒感染中,CD81是病毒進入細胞的關鍵受體之一,因此其表達水平的變化可能影響病毒的感染效率和疾病的進展。此外,CD81還與某些自身免疫性疾病、腫瘤以及感染性疾病的發病機制有關。

熱銷產品

CD81 Recombinant Monoclonal Antibody

驗證數據

WB
CSB-RA004960A0HU WB

Positive WB detected in:K562 whole cell lysate
All lanes:CD81 antibody at 1.25μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 26 KDa
Observed band size: 26 KDa

FITC
CSB-RA004960A0HU FITC

Overlay histogram showing Jurkat cells stained with CSB-RA004960A0HU (red line) at 1:50. The cells were fixed with 70% Ethylalcohol (18h) and then permeabilized with 0.3% Triton X-100 for 2 min.The cells were then incubated in 1x PBS /10% normal goat serum to block non-specific protein-protein interactions followed by primary antibody for 1 h at 4°C.The secondary antibody used was FITC goat anti-rabbit IgG (H+L) at 1/200 dilution for 1 h at 4°C. Control antibody (green line) was used under the same conditions. Acquisition of >10,000 events was performed.

IHC
CSB-RA004960A0HU IHC-1

IHC image of CSB-RA004960A0HU diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC
CSB-RA004960A0HU IHC-2

IHC image of CSB-RA004960A0HU diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.


CD81 Antibodies

CD81 for Mus musculus (Mouse)

CD81 for Homo sapiens (Human)

CD81 Proteins

CD81 Proteins for Mus musculus (Mouse)

CD81 Proteins for Homo sapiens (Human)

CD81 Proteins for Pan troglodytes (Chimpanzee)

CD81 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

CD81 Proteins for Bos taurus (Bovine)

CD81 Proteins for Rattus norvegicus (Rat)

CD81 Proteins for Saguinus oedipus (Cotton-top tamarin)

CD81 ELISA Kit

CD81 ELISA Kit for Homo sapiens (Human)

CD81 ELISA Kit for Mus musculus (Mouse)



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