在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Horse Estrogen receptor (ESR1), partial

  • 中文名稱:
    Recombinant Horse Estrogen receptor(ESR1) ,partial
  • 貨號:
    CSB-YP886955HO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Horse Estrogen receptor(ESR1) ,partial
  • 貨號:
    CSB-EP886955HO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Horse Estrogen receptor(ESR1) ,partial
  • 貨號:
    CSB-EP886955HO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Horse Estrogen receptor(ESR1) ,partial
  • 貨號:
    CSB-BP886955HO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Horse Estrogen receptor(ESR1) ,partial
  • 貨號:
    CSB-MP886955HO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    ESR1; ESR; NR3A1Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
  • 種屬:
    Equus caballus (Horse)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial association with multiprotein coactivator complexes through LXXLL motifs of their respective components. Mutual transrepression occurs between the estrogen receptor (ER) and NF-kappa-B in a cell-type specific manner. Decreases NF-kappa-B DNA-binding activity and inhibits NF-kappa-B-mediated transcription from the IL6 promoter and displace RELA/p65 and associated coregulators from the promoter. Recruited to the NF-kappa-B response element of the CCL2 and IL8 promoters and can displace CREBBP. Present with NF-kappa-B components RELA/p65 and NFKB1/p50 on ERE sequences. Can also act synergistically with NF-kappa-B to activate transcription involving respective recruitment adjacent response elements; the function involves CREBBP. Can activate the transcriptional activity of TFF1. Also mediates membrane-initiated estrogen signaling involving various kinase cascades.Essential for MTA1-mediated transcriptional regulation of BRCA1 and BCAS3.
  • 基因功能參考文獻:
    1. The presence of a single isoform of ESR1 (66kDa) and ESR2 (61kDa) was found by Western-blot analysis in samples from seven stallions and the expression of the seven transmembrane estradiol binding receptor GPER in colt testis. PMID: 24607572
    2. The spatial arrangement of estrogen receptor alpha during early pregnancy showed cytoplasmic staining of endometrial epithelia and in the nuclei of occasional stromal cells. PMID: 22176887
    3. expression of estrogen receptor alpha and beta and progesterone receptor in equine microplacentomes gives evidence for a role of placental steroids as regulators of placental function PMID: 18992099
  • 亞細胞定位:
    Nucleus. Cytoplasm. Golgi apparatus. Cell membrane.
  • 蛋白家族:
    Nuclear hormone receptor family, NR3 subfamily
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲精品无码人妻无码| 无码人妻精品一区二区三区66| 成人aaa片一区国产精品| 精品久久久久久亚洲综合网 | 中文字幕乱码人在线视频1区| 亚洲另类欧美在线电影| 大屁股熟女一区二区三区| 亚洲第一aaaaa片| 国产麻豆精品av在线观看| 欧美亚洲色欲色一欲www| 一本一本久久a久久精品综合麻豆| 色窝窝无码一区二区三区成人网站| 吃奶呻吟打开双腿做受在线视频| 国产精品亚洲а∨天堂免下载| 饥渴少妇高潮视频大全| 亚洲男人的天堂av手机在线观看| 亚洲精品无码不卡| 婷婷四房综合激情五月在线| 国产午夜精品免费一区二区三区| 99久e在线精品视频在线 | 午夜寂寞少妇aaa片毛片| 少妇饥渴偷公乱av在线观看涩爱| 裸体丰满白嫩大尺度尤物| 欧美人与动牲猛交a欧美精品| 丰满人妻熟妇乱又伦精品视| 碰超免费人妻中文字幕| 中文字幕av无码免费一区| 在线成人一区二区| 欧美国产日韩a在线视频| 在线精品国精品国产尤物| 国产精品人妻在线观看| 99国产精品久久久久久久日本竹| 亚洲日韩欧美一区二区三区在线 | 国产精品卡一卡2卡三卡网站| 欧美顶级少妇作爱| 亚洲欧美中文日韩在线视频一| 成年女人看片永久免费视频| 久久久久久久久久久久久9999 | 成 人 在 线 免费观看| 一本一道色欲综合网| 日韩一区二区三区高清电影|