在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. L2HGDH Antibody

L2HGDH Antibody

  • 中文名稱：
    L2HGDH兔多克隆抗體
  • 貨號：
    CSB-PA864008LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: L2HGDH antibody at 8µg/ml + K562 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 51, 49 kDa
      Observed band size: 51 kDa
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA864008LA01HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) L2HGDH Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    L2HGDH
  • 別名：
    2 hydroxyglutarate dehydrogenase antibody; Alpha hydroxyglutarate oxidoreductase antibody; Alpha ketoglutarate reductase antibody; C14orf160 antibody; Duranin antibody; FLJ12618 antibody; L alpha hydroxyglutarate dehydrogenase antibody; L-2-hydroxyglutarate dehydrogenase antibody; L-2-hydroxyglutarate dehydrogenase, mitochondrial antibody; L2HDH_HUMAN antibody; l2hgdh antibody; mitochondrial antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human L-2-hydroxyglutarate dehydrogenase, mitochondrial protein (52-463AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，L2HGDH Antibody (CSB-PA864008LA01HU)，的標記方式是Non-conjugated。對于L2HGDH Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA864008LB01HU L2HGDH Antibody, HRP conjugated ELISA
    FITC CSB-PA864008LC01HU L2HGDH Antibody, FITC conjugated
    Biotin CSB-PA864008LD01HU L2HGDH Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 基因功能參考文獻：
    1. In this study, we describe a large pedigree from Pakistan showing multiple neurological symptoms. Homozygosity mapping and Sanger sequencing revealed a novel missense mutation in L2HGDH gene. PMID: 29458334
    2. The mutations of the L2HGDH gene as the causes of L-2-hydroxyglutaric aciduria. PMID: 29980873
    3. c.845G>A (p.R282Q) in the exon 7 of the L2HGDH gene is associated with 2-hydroxyglutaric aciduria in Chinese family. PMID: 26829733
    4. Intragenic single nucleotide length polymorphisms and two extragenic microsatellites flanking the L2HGDH gene confirm the founder effect of c.241A>G mutation in the 14 studied cases. PMID: 24573090
    5. modest increases in intracellular 2-HG in acute myeloid leukaemia cells, as seen with the rs11554137 SNP, might enhance chemoresistance, or promote acquisition of leukaemia-iniating mutations PMID: 24606602
    6. Report ten novel mutations in the L2HGDH gene in patients with L-2-hydroxyglutaric aciduria from different ethnic backgrounds. PMID: 18415700
    7. Report three unrelated Tunisian families containing seven patients with L2HGA mutations and inter-familial phenotype variability. PMID: 18780161
    8. L2HGDH mutation is not associated with glioblastoma. PMID: 21625441
    9. We did not find evidence for mutations in the genes D2HGDH and L2HGDH as an alternative mechanism for raised 2-hydroxyglutarate levels in brain tumours PMID: 20727073
    10. Exonic mutations in the L2HGDH gene in Staffordshire bull terriers have been identified and associated with epilepsy. PMID: 20852250
    11. analysis of genetic heterogeneity in D-2-hydroxyglutaric aciduria PMID: 20020533
    12. The phenotype, including neurological manifestations and urinary levels of alpha-hydroxyglutarate, is reported and the phenotype-genotype relationship, is evaluated. PMID: 20052767
    13. we present three novel mutations (Gln197X, Gly211Val and c.540+1 G>A), which increase the present deleterious collection of L2HGDH gene up to 35 mutationsthat we have compiled in this study. PMID: 19911013
    14. encodes a putative mitochondrial protein with homology to FAD-dependent oxidoreductases; a mutant gene is accociated with L-2-hydroxyglutaric aciduria.propose to name the gene duranin PMID: 15385440
    15. data indicate that l-2-hydroxyglutaric aciduria is due to a deficiency in l-2-hydroxyglutarate dehydrogenase PMID: 16005139
    16. Indicate that 2-ketoglutaric acid is the metabolic precursor of L-2-hydrosyglutaric acid in L-2-hydroxyglutaric acid aciduria. PMID: 17876720
    17. We successfully treated an adult patient with L-2-hydroxyglutaric aciduria using FAD and levocarnitine. PMID: 18362286
    18. Data show that L-2-hydroxyglutaric aciduria and brain tumors in children with mutations in the L2HGDH gene in exon 3 (c.292C-->T) and in exon 7 (c.887T-->A). PMID: 18671189

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    L-2-hydroxyglutaric aciduria (L2HGA)
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    L2HGDH family
  • 組織特異性：
    Widely expressed. Highly expressed in brain, testis and muscle. Expressed to a lower extent in lymphocytes, fibroblasts, keratinocytes, placenta, bladder, small intestine, liver and bone marrow.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 20499

    OMIM: 236792

    KEGG: hsa:79944

    STRING: 9606.ENSP00000267436

    UniGene: Hs.256034



主站蜘蛛池模板： 四库影院永久四虎精品国产| 男女啪啪高清无遮挡免费| 国产福利一区二区三区在线视频| 女人脱了内裤趴开腿让男躁| 国产中文字字幕乱码无限| 天天躁日日躁狠狠很躁| 日日噜噜夜夜狠狠久久丁香五月 | 99久久er这里只有精品18| 丰满少妇高潮惨叫久久久一| 曰本大码熟中文字幕| 精品无码一区在线观看| 日产精品一二三区| 性久久久久久久| 久久精品a亚洲国产v高清不卡 | av在线播放日韩亚洲欧我不卡| 久久无码人妻一区二区三区午夜| 欧美乱妇日本无乱码特黄大片| 欧美一区内射最近更新| 国产在线观看无码的免费网站| 2021最新精品国自产拍视频| 乱子伦农村xxxxbbb| 亚洲乱码伦小说区| 国产人久久人人人人爽| 日产亚洲一区二区三区| 奇米777四色在线精品| 在线不卡av片免费观看| 特黄aaaaaaa片免费视频| 99久热在线精品视频观看| 97一区二区国产好的精华液| 国产xxxx69真实实拍| 亚洲a片成人无码久久精品色欲| 日韩一区二区三区无码人妻视频| 中出人妻中文字幕无码| 亚洲 激情 小说 另类 欧美| 色婷婷五月综合欧美图片| 亚洲另类欧美综合久久图片区| 色偷偷色噜噜狠狠网站久久| 国产精品永久免费| 熟女少妇人妻黑人sirbao| 一本加勒比hezyo中文无码| 国产成人无码av一区二区在线观看|